The study aims to understand the anatomic feasibility of multibranched Zenith t-Branch as a treatment for TAAA (thoracoabdominal aortic aneurysms) in females.

The study takes 268 patients who suffered from TAAA and were treated with open/endovascular repair (2007 – 2019). The researchers conducted a retrospective study to understand the feasibility of Zenith t-Branch in accordance with the instruction of use from the manufacturer.

The researchers studied anatomical feasibility factors like vascular access, visceral vessels, and aortic anatomy. They stratified the results by sex and compared. They used a logistic regression model to understand the association between the factors or other variables.

The overall feasibility was 39% and was negatively associated with the female. The vascular access feasibility was 61% in females and 89% in males. The aorta feasibility was 52% in females and 69% in males. The visceral vessel feasibility was 78% in females and 73% in males. The aortic feasibility was 45% in females and 6% in males. The orientation and location of the vessels had adequate accuracy.

Although 1/3rd of the patients with the condition were treated with Zenith t-Branch, only 22% of females were chosen because of sex-based anatomical limitations. The researchers recommended further studies to understand the new generation of such multibranched devices.