Here are what the editors at HealthDay consider to be the most important developments in Pediatrics for February 2019. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Teens’ Social Media Use Does Not Predict Later Depression

THURSDAY, Feb. 28, 2019 (HealthDay News) — Social media use does not predict later depressive symptoms among adolescents or college undergraduates, according to a study recently published in Clinical Psychological Science.

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ATS Issues Practice Guideline for Pediatric Home Oxygen Therapy

THURSDAY, Feb. 28, 2019 (HealthDay News) — Recommendations have been developed for home oxygen therapy in children with chronic respiratory conditions; the clinical practice guideline from the American Thoracic Society was published in the Feb. 1 issue of the American Journal of Respiratory and Critical Care Medicine.

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Prenatal Vitamin Intake in Early Pregnancy May Cut Autism Risk

WEDNESDAY, Feb. 27, 2019 (HealthDay News) — Maternal prenatal vitamin intake during the first month of pregnancy is associated with a reduced risk for autism spectrum disorder (ASD) in siblings of children with ASD, according to a study published online Feb. 27 in JAMA Psychiatry.

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Green Space in Childhood Tied to Better Mental Health Later

WEDNESDAY, Feb. 27, 2019 (HealthDay News) — Living around high levels of green space during childhood is associated with a lower risk for a wide spectrum of psychiatric disorders later in life, according to a study published online Feb. 25 in the Proceedings of the National Academy of Sciences.

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Antenatal Corticosteroid Tx Tied to Reduction in Birth Size

WEDNESDAY, Feb. 27, 2019 (HealthDay News) — Antenatal corticosteroid therapy (ACT) is associated with reductions in birth size for infants, according to a study published online Feb. 26 in PLOS Medicine.

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Rate of Opioid Rx Stable After Pediatric Outpatient Surgery

WEDNESDAY, Feb. 27, 2019 (HealthDay News) — From 2013 to 2017, the rate of receiving a take-home opioid prescription remained stable after pediatric outpatient surgery as did the dose prescribed, but the maximum take-home dose declined, according to a study recently published in Pain Medicine.

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Environmental Exposures Before, After Birth Tied to Lung Function

TUESDAY, Feb. 26, 2019 (HealthDay News) — Exposure to several chemicals before and after birth appears to be associated with a decrease in lung function later in childhood, according to a study published in the February issue of The Lancet Planetary Health.

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Classroom Initiative Ups Participation in School Breakfast

TUESDAY, Feb. 26, 2019 (HealthDay News) — A breakfast-in-the-classroom initiative increases participation in the federal School Breakfast Program but has an unintended consequence of increasing the incidence and prevalence of obesity, according to a study published online Feb. 25 in JAMA Pediatrics.

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Prediction Rule IDs Febrile Infants 0 to 2 Months Old at Low Risk for SBIs

TUESDAY, Feb. 26, 2019 (HealthDay News) — A new prediction rule can accurately identify febrile infants aged ≤60 days at low risk for serious bacterial infections (SBIs) using urinalysis, absolute neutrophil count (ANC), and procalcitonin levels, according to a study published online Feb. 18 in JAMA Pediatrics.

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Genetic Variant Tied to Leukemia Risk in Hispanic Children

MONDAY, Feb. 25, 2019 (HealthDay News) — Genetic variations have been identified in the ERG gene that are associated with an increased risk for acute lymphoblastic leukemia (ALL) in Hispanic children, according to a study recently published in Blood.

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Nonmedical Rx Opioid Use in Teens Linked to Parental Use

MONDAY, Feb. 25, 2019 (HealthDay News) — Nonmedical prescription opioid (NMPO) use in adolescents is associated with parental NMPO use and with smoking and parent-adolescent conflict, according to a study published online Feb. 25 in Pediatrics.

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2014 to 2017 Saw Improvement in Burnout for U.S. Physicians

MONDAY, Feb. 25, 2019 (HealthDay News) — From 2014 to 2017, there was an improvement in burnout and satisfaction with work-life integration among U.S. physicians, according to a study published online Feb. 22 in the Mayo Clinic Proceedings.

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National Health Spending Set to Increase 5.5 Percent Annually

FRIDAY, Feb. 22, 2019 (HealthDay News) — National health spending is projected to increase at an annual rate of 5.5. percent from 2018 to 2027, with fundamental economic and demographic factors the main drivers, according to a report published online Feb. 20 in Health Affairs.

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Most Patients Do Not Disclose Complementary Medicine Use

FRIDAY, Feb. 22, 2019 (HealthDay News) — Just one-third of users of biologically based complementary medicine (CM) disclose their use to traditional health care providers, according to a review published online Feb. 7 in Scientific Reports.

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8 More U.S. Communities to Be Assessed for PFAS Toxin Exposure

THURSDAY, Feb. 21, 2019 (HealthDay News) — Eight additional communities near current or former U.S. military installations that will be included in assessments of human exposure to perfluoroalkyl and polyfluoroalkyl substances (PFAS) were announced Thursday by federal officials.

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FDA Advances Regulation to Ensure Sunscreen Safety, Efficacy

THURSDAY, Feb. 21, 2019 (HealthDay News) — The U.S. Food and Drug Administration took steps Thursday to tighten regulation of over-the-counter sunscreen products.

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2005 to 2015 Saw Drop in Primary Care Physician Supply

THURSDAY, Feb. 21, 2019 (HealthDay News) — From 2005 to 2015, there was a decrease in primary care physician supply per capita in the United States, with increased supply associated with lower mortality, according to a study published online Feb. 18 in JAMA Internal Medicine.

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Vertical Integration Has Little Impact on Quality Measures

THURSDAY, Feb. 21, 2019 (HealthDay News) — Vertical integration between hospitals and physicians has little impact on quality measures, while increased hospital market concentration is strongly associated with reduced quality in measures of patient satisfaction, according to a study published online Feb. 9 in Medical Care Research and Review.

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New Kaiser Permanente Medical School Plans to Waive Tuition

WEDNESDAY, Feb. 20, 2019 (HealthDay News) — A new medical school to be opened by California-based health system Kaiser Permanente will waive tuition for all students in its first five graduating classes.

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FDA Head Says Feds May Intervene to Cut Vaccine Exemptions

WEDNESDAY, Feb. 20, 2019 (HealthDay News) — The U.S. government may have to take steps to reduce vaccine exemptions for children if states do not do it, the head of the U.S. Food and Drug Administration suggested. His comments come as measles outbreaks rage in a number of states. Those outbreaks could have been prevented if children had all been vaccinated. But nearly all states allow children to attend school even if their parents opt out of inoculation programs, CNN reported.

CNN Article

1997 to 2014 Saw Large Hike in Screen Time for Ages 0 to 2

WEDNESDAY, Feb. 20, 2019 (HealthDay News) — Between 1997 and 2014, screen time more than doubled for children aged 0 to 2 years, with television time accounting for most screen time, according to a research letter published online Feb. 18 in JAMA Pediatrics.

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Prenatal Fluconazole Exposure Increases Neonatal Risks

WEDNESDAY, Feb. 20, 2019 (HealthDay News) — Maternal exposure to fluconazole during pregnancy may increase the risk for spontaneous abortion, according to a study published online Feb. 19 in CMAJ, the journal of the Canadian Medical Association.

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CDC: Salmonella Cases Tied to Raw Turkey Products Now at 279

TUESDAY, Feb. 19, 2019 (HealthDay News) — Sixty-three more cases of illness in a Salmonella outbreak linked to raw turkey products have been reported since Dec. 21, 2018, bringing the total number to 279, the U.S. Centers for Disease Control and Prevention says in an update.

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Lower Self-Perception Observed in Children With Amblyopia

TUESDAY, Feb. 19, 2019 (HealthDay News) — Children with amblyopia have significantly lower mean peer acceptance and physical competence scores at age 3 to 7 years, according to a study published online Feb. 14 in JAMA Ophthalmology.

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FDA Approves First Customizable Insulin Pump

FRIDAY, Feb. 15, 2019 (HealthDay News) — The Tandem Diabetes Care t:Slim X2 insulin pump, which allows a patient to customize treatment, has been approved by the U.S. Food and Drug Administration.

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Hospital Prices Growing Faster Than Physician Prices

FRIDAY, Feb. 15, 2019 (HealthDay News) — Growth in hospital prices and payments outpaced growth in physician prices and payments from 2007 through 2014, according to a report published in the February issue of Health Affairs.

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Brief Anesthesia in Infancy Does Not Mar Neurodevelopment

FRIDAY, Feb. 15, 2019 (HealthDay News) — Neurodevelopmental outcomes at 5 years of age are equivalent after brief general anesthesia or awake-regional anesthesia in infancy, according to a study published in the Feb. 16 issue of The Lancet.

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CDC: Severity of Influenza Season Low Through Feb. 2, 2019

THURSDAY, Feb. 14, 2019 (HealthDay News) — The 2018 to 2019 influenza season has been low in severity so far, and overall vaccine effectiveness is about 47 percent, according to two reports published in the Feb. 15 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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High Rates of MenB Vaccination Advised in University Outbreaks

THURSDAY, Feb. 14, 2019 (HealthDay News) — Achieving high serogroup B meningococcal (MenB) vaccination coverage is recommended following university-based outbreaks of meningococcal disease caused by serogroup B, according to a study published online Feb. 13 in the U.S. Centers for Disease Control and Prevention Emerging Infectious Diseases.

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Child Enterovirus Infection May Up Risk for Developing Celiac Disease

THURSDAY, Feb. 14, 2019 (HealthDay News) — A higher frequency of enterovirus infections in early childhood is associated with an increased risk for developing celiac disease, according to a study published online Feb. 13 in the The BMJ.

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Human Milk Microbiota Shaped by Maternal Factors, Feeding Method

THURSDAY, Feb. 14, 2019 (HealthDay News) — Compared with direct breastfeeding, indirect breastfeeding with pumped milk is associated with the depletion of oral bacteria and a higher abundance of potential pathogens, according to a study published in the Feb. 13 issue of Cell Host & Microbe.

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Subsymptom Threshold Exercise Speeds Concussion Recovery

THURSDAY, Feb. 14, 2019 (HealthDay News) — For adolescent athletes, subsymptom threshold aerobic exercise prescribed during the first week after sport-related concussion (SRC) speeds recovery, according to a study published online Feb. 4 in JAMA Pediatrics.

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Obesity Linked to Adverse Events in Children With Leukemia

WEDNESDAY, Feb. 13, 2019 (HealthDay News) — For children with acute lymphoblastic leukemia (ALL), obesity is associated with an increased risk for adverse events during premaintenance chemotherapy, according to a study published in the February issue of Pediatric Blood & Cancer.

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Progress Made in Developing New Antibacterial Agents

WEDNESDAY, Feb. 13, 2019 (HealthDay News) — Although there has been progress in the development of new antibacterial drugs, most of the recently approved agents have been modifications of existing chemical classes of antibiotics, according to research published online Feb. 1 in Clinical Infectious Diseases.

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Lower Birth Weight May Up Risk for Psychiatric Disorders

WEDNESDAY, Feb. 13, 2019 (HealthDay News) — After adjustment for family-related factors and gestational age, lower birth weight is associated with a small but significant increased risk for several psychiatric disorders, according to a study published online Feb. 6 in JAMA Psychiatry.

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CDC: Student Tobacco Use Increased From 2017 to 2018

TUESDAY, Feb. 12, 2019 (HealthDay News) — From 2017 to 2018, there was an increase in any tobacco use, especially electronic cigarette use, for high school and middle school students, according to research published online Feb. 11 in the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Health Care Spending Per Person Increased to $5,641 in 2017

TUESDAY, Feb. 12, 2019 (HealthDay News) — In 2017, health care spending per person reached $5,641, according to the Health Care Cost Institute (HCCI) annual Health Care Cost and Utilization Report.

Health Care Cost and Utilization Report

Many Systematic Reviews Do Not Fully Report Adverse Events

TUESDAY, Feb. 12, 2019 (HealthDay News) — Many systematic review protocols in the International Prospective Register of Systematic Reviews (PROSPERO) do not include adverse event reporting, according to a study published in the April issue of the Journal of Clinical Epidemiology.

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Acne Relapses Linked to Lower Quality of Life, Productivity

TUESDAY, Feb. 12, 2019 (HealthDay News) — Acne relapses are significantly associated with impaired quality of life as well as productivity loss and absenteeism, according to a study recently published in the Journal of the European Academy of Dermatology and Venereology.

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CDC: Screening Policies for Critical Congenital Heart Dz Widespread

TUESDAY, Feb. 12, 2019 (HealthDay News) — All 50 states and the District of Columbia have implemented newborn screening policies for critical congenital heart disease (CCHD), although there are opportunities for improving data collection, according to research published in the Feb. 8 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Low Fitness, Obesity Linked to Later Disability Pension

MONDAY, Feb. 11, 2019 (HealthDay News) — Among men, low cardiorespiratory fitness and obesity in adolescence are associated with an increased risk for later receipt of a disability pension, according to a study published online Feb. 12 in the Annals of Internal Medicine.

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Many Children Not Receiving Needed Mental Health Treatment

MONDAY, Feb. 11, 2019 (HealthDay News) — About half of the estimated 16.5 percent of U.S. children with a treatable mental health disorder do not receive needed treatment from a mental health professional, according to a research letter published online Feb. 11 in JAMA Pediatrics.

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Children With Autism More Often Have Sleep Problems

MONDAY, Feb. 11, 2019 (HealthDay News) — More children with autism spectrum disorder (ASD) have sleep problems compared with other children, according to a study published online Feb. 11 in Pediatrics.

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Smaller Germinal Centers Identified in Recurrent Tonsillitis

MONDAY, Feb. 11, 2019 (HealthDay News) — Children with recurrent tonsillitis (RT) have smaller germinal centers, according to a study published in the Feb. 6 issue of Science Translational Medicine.

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Measles Outbreak Triggers Sharp Rise in Demand for Vaccine

FRIDAY, Feb. 8, 2019 (HealthDay News) — Health clinics in Clark County, Washington, are scrambling to meet the sharply increased demand for measles vaccination as people seek protection during an outbreak of the highly contagious virus.

Kaiser Health News Article

Johnson & Johnson to Provide Drug Prices in TV Ads

FRIDAY, Feb. 8, 2019 (HealthDay News) — In a drug industry first, Johnson & Johnson will start giving the list prices of its prescription drugs in television ads.

AP News Article

Walgreens Worst Violator in Tobacco Sales to Minors, FDA Says

FRIDAY, Feb. 8, 2019 (HealthDay News) — Walgreens’ high rate of violations for selling tobacco products to minors has led U.S. Food and Drug Administration Commissioner Scott Gottlieb, M.D., to ask for a meeting with the company to discuss the issue.

CNN Article
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Vaccine-Preventable Infections Common After Peds Transplant

FRIDAY, Feb. 8, 2019 (HealthDay News) — Hospitalization for vaccine-preventable infections occurs in more than 15 percent of pediatric solid organ transplant recipients in the first five years after surgery, according to a study recently published in JAMA Pediatrics.

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Parents Conflicted About Opioid Use in Children

THURSDAY, Feb. 7, 2019 (HealthDay News) — Parents are conflicted about the use of prescribed opioids in children, with most concerned about side effects and risks but believing opioids are the most effective option for managing pain, according to a survey commissioned by the American Society of Anesthesiologists (ASA) and released to coincide with Physician Anesthesiologists Week, held from Jan. 27 to Feb. 2.

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Many Children Not Following Toothbrushing Recommendations

THURSDAY, Feb. 7, 2019 (HealthDay News) — Most children are not brushing their teeth early enough, and many are not using the proper amount of toothpaste, according to research published in the Feb. 1 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Drug Combo Tolerated in Younger Children With Cystic Fibrosis

THURSDAY, Feb. 7, 2019 (HealthDay News) — Lumacaftor/ivacaftor treatment is generally safe and well tolerated for children aged 2 to 5 years with cystic fibrosis (CF) homozygous for the F508del-CFTR mutation, according to a study published online Jan. 24 in The Lancet Respiratory Medicine.

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Recommendations Updated for Tonsillectomy in Children

WEDNESDAY, Feb. 6, 2019 (HealthDay News) — Recommendations have been updated for tonsillectomy in children; the revised clinical practice guideline was published in a supplement to the February issue of Otolaryngology-Head and Neck Surgery.

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Reading, Math Scores No Different for Children With T1DM

TUESDAY, Feb. 5, 2019 (HealthDay News) — Standardized reading and mathematics scores do not differ significantly for public schoolchildren with and without type 1 diabetes, according to a study published in the Feb. 5 issue of the Journal of the American Medical Association.

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California Bill Would Tighten Controls on Children’s Genitalia Surgery

TUESDAY, Feb. 5, 2019 (HealthDay News) — A bill that would place more restrictions on children’s genitalia surgery in California raises serious concerns among doctors in the state. Under the bill, doctors would not be able to treat or perform surgery on children born with genitals that do not match a single gender or are otherwise atypical unless such surgery is medically necessary or the child consents, the Associated Press reported.

AP News Article

No Increased Risk for Cancer for ART-Conceived Children

TUESDAY, Feb. 5, 2019 (HealthDay News) — Children conceived by assisted reproductive technology (ART) do not appear to have a significantly increased cancer risk, according to a study published online Feb. 4 in Human Reproduction.

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Few Teens Meet Sleep, Exercise, Screen-Time Guidelines

TUESDAY, Feb. 5, 2019 (HealthDay News) — Few adolescents meet sleep, physical activity, and screen-time guidelines concurrently, according to a study published online Feb. 4 in JAMA Pediatrics.

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AAP Releases 2019 Childhood Immunization Schedules

TUESDAY, Feb. 5, 2019 (HealthDay News) — The 2019 recommended childhood and adolescent immunization schedules have been issued by the American Academy of Pediatrics and published online Feb. 5 in Pediatrics.

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Washington State Measles Cases Now at 48 Since Jan. 1

MONDAY, Feb. 4, 2019 (HealthDay News) — There have been 48 confirmed cases of measles in Washington state since the start of the year as health officials struggle to stop the spread of the infectious disease.

CNN Article

E-Cigarette Use Linked to Cigarette Initiation in Adolescents

MONDAY, Feb. 4, 2019 (HealthDay News) — Electronic cigarette use is associated with an increased risk for cigarette initiation and use in adolescents, according to a study published online Feb. 1 in JAMA Network Open.

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After Elbow Surgery, Children May Be Overprescribed Opioids

MONDAY, Feb. 4, 2019 (HealthDay News) — Opioids may be overprescribed to children after orthopedic surgery for supracondylar humerus fractures, according to a study published in the Jan. 16 issue of The Journal of Bone & Joint Surgery.

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Unrestrained Driver Predicts Unrestrained Child Passenger

MONDAY, Feb. 4, 2019 (HealthDay News) — An unrestrained driver is a strong predictor for having an unrestrained child passenger in both fatal and nonfatal crashes, according to a study published online Feb. 4 in Pediatrics.

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Most Students Receiving Spectacles Wear Them at Follow-Up

FRIDAY, Feb. 1, 2019 (HealthDay News) — Three-quarters of students aged 11 to 15 years from government schools in India receiving spectacles wear them at follow-up, according to a study published online Jan. 31 in JAMA Ophthalmology.

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HPV Educational Video May Increase Vaccination Rates

FRIDAY, Feb. 1, 2019 (HealthDay News) — Educational videos in pediatric clinics can increase rates of human papillomavirus (HPV) vaccination among adolescents, according to a study published in the January issue of Pediatrics.

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Maternal Glucose in Pregnancy Tied to Child’s Glucose Outcomes

FRIDAY, Feb. 1, 2019 (HealthDay News) — In utero exposure to higher levels of maternal glucose is associated with higher glucose levels and insulin resistance during childhood, according to a study published online Jan. 7 in Diabetes Care.

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