The following is a summary of “Lymphedematous Fibroepithelial Polyp Without Associated Condom Catheter Use: A Case Report With Review of the Literature,” published in the July 2023 issue of Dermatopathology by Zeches et al.
Lymphedematous fibroepithelial polyps are uncommon protrusions of the glans penis that are commonly associated with chronic condom catheter use. To our knowledge, less than twenty cases with a relatively similar clinical presentation have been reported in the medical literature. Surgical excision was performed on a 74-year-old male with a lymphedematous fibroepithelial polyp unrelated to condom use.
The lesion displayed a hypocellular proliferation of spindled and stellate fibroblasts with intermixed Touton-like giant cells embedded within an edematous stroma with thickened vasculature on histopathological examination. Immunohistochemical profiling reveals a robust immunoreactivity for smooth muscle actin, a moderate positivity for factor XIIIa, and no immunoreactivity for CD34 or desmin.
In addition, the researchers examined the reported spectrum of clinical and histopathological characteristics of this entity as well as the numerous hypotheses regarding its pathogenesis. They aim to raise awareness and improve the diagnostic accuracy of this entity, which could affect clinical management.