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Four close related HIV-1 CRF01_AE/CRF07_BC Recombinant Forms identified in east China.

Four close related HIV-1 CRF01_AE/CRF07_BC Recombinant Forms identified in east China.
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Li F, Li Y, Feng Y, Hu J, Ruan Y, Xing H, Shao Y,


Li F, Li Y, Feng Y, Hu J, Ruan Y, Xing H, Shao Y, (click to view)

Li F, Li Y, Feng Y, Hu J, Ruan Y, Xing H, Shao Y,

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AIDS research and human retroviruses 2017 03 16() doi 10.1089/AID.2017.0049

Abstract

Five near full-length genome of novel second-generation HIV-1 recombinant virus (JS150021, JS150029, JS150129, JS150132 and AH150183) were identified from five HIV-positive people in Jiangsu and Anhui province, east China. Phylogenic analyses showed that these five sequences are all composed of two well-established circulating recombinant forms CRF07_BC and CRF01_AE, grouped into four new discovered recombinant forms ,which show several very similar but not identical recombinant breakpoints. The four recombinant forms are also identified to be a sort of family or related viruses, seems to be the results of different recombination events. The emergence of a serious new closed related CRF07_BC/CRF01_AE recombinant strain indicate the increasing complexity sexual transmission of the HIV-1 epidemic in China.

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