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High prevalence of syphilis, HBV and HCV co-infection, and low rate of effective vaccination against hepatitis B in HIV-infected patients in West China hospital.

High prevalence of syphilis, HBV and HCV co-infection, and low rate of effective vaccination against hepatitis B in HIV-infected patients in West China hospital.
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Yang T, Chen Q, Li D, Wang T, Gou Y, Wei B, Tao C,


Yang T, Chen Q, Li D, Wang T, Gou Y, Wei B, Tao C, (click to view)

Yang T, Chen Q, Li D, Wang T, Gou Y, Wei B, Tao C,

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Journal of medical virology 2017 08 09() doi 10.1002/jmv.24912

Abstract

Background and Aims To investigate the epidemiological features and risk factors of HBV, HCV and syphilis infection among HIV-infected patients in West China Hospital. Methods A retrospective study was conducted with HIV-infected patients from 2014 to 2016 in West China hospital, SCU. Serum makers for HBV, HCV and syphilis were detected. Results Among 894 HIV-infected patients, the prevalence of HIV/HBV, HIV/HCV, HIV/syphilis co-infections was 14.4%, 5.7%, and 18.9% respectively. HIV/HBV/HCV, HIV/HCV/syphilis and HIV/HBV/syphilis triple co-infection was 7 (0.7%), 12(1.3%), 29(3.2%) respectively. The rate of effective vaccination against HBV was only 7.7% in HIV-infected patients. Age (OR = 0.243 95% CI: 0.114 -0.518), ethnicity (OR = 3.654 95% CI: 1.849-7.218) and education level (OR = 0.140 95% CI: 0.033-0.606) are risk factors affecting HIV/HCV co-infection. Conclusions A high prevalence of HIV/syphilis, HIV/HBV and HIV/ HCV co-infection can be observed in west China. The rate for HIV-infected patients who were effectively vaccinated against HBV was fewer than 10%. This article is protected by copyright. All rights reserved.

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