For a study, aging was followed by physiological changes that impacted body composition and functionality, such as fat growth at the expense of muscular mass, which had implications for morbidity and quality of life. The gut microbiome had lately emerged as a vital environmental regulator of human health that had the potential to influence healthy aging and possibly longevity. However, the link between it and adiposity in old age was still unknown. Researchers used 16S rRNA amplicon sequencing to evaluate the gut microbiota in a well-characterized cohort of 201 Italian aged people from the NU-AGE project. Next, researchers used dual-energy X-ray absorptiometry (DXA) to see if there was a link between body composition and visceral and subcutaneous adipose tissue. Other health-related factors were also examined such as Dietary patterns and the serum metabolome. The researchers found out the compositional features of the elderly gut microbiota were found to be linked with DXA values, nutrition, metabolic profiles, and cardio-metabolic risk factors.

 

Refe:www.tandfonline.com/doi/full/10.1080/19490976.2021.1880221