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History of mood or anxiety disorders and risk of gestational diabetes mellitus in a population-based cohort.

History of mood or anxiety disorders and risk of gestational diabetes mellitus in a population-based cohort.
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Beka Q, Bowker S, Savu A, Kingston D, Johnson JA, Kaul P,


Beka Q, Bowker S, Savu A, Kingston D, Johnson JA, Kaul P, (click to view)

Beka Q, Bowker S, Savu A, Kingston D, Johnson JA, Kaul P,

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Diabetic medicine : a journal of the British Diabetic Association 2017 11 09() doi 10.1111/dme.13543
Abstract
AIM
To examine the association between mood and anxiety disorders and the development of gestational diabetes mellitus in a retrospective population-based cohort study.

METHODS
Clinical data from a provincial perinatal health registry were linked to physician claims, hospitalization records and emergency visits to identify any diagnoses of mood or anxiety disorders in the 2 years prior to pregnancy and a subsequent diagnosis of gestational diabetes during pregnancy. The study population included all singleton pregnancies in the Canadian province of Alberta from 1 April 2000 to 31 March 2010. Generalized estimating equations were used to determine the adjusted odds ratio of gestational diabetes, comparing women with and without a history of mood or anxiety disorders.

RESULTS
Among 373 674 pregnancies from 253 911 women, 25.7% had a history of mood or anxiety disorders, and 3.8% developed gestational diabetes. The multivariate-adjusted odds of developing gestational diabetes were higher among women with a history of mood or anxiety disorders (odds ratio 1.10, 95% CI 1.06-1.14).

CONCLUSIONS
Women with a history of mood or anxiety disorders had a moderately increased risk of developing gestational diabetes. This article is protected by copyright. All rights reserved.

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