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Human herpesvirus-6 encephalitis following chemotherapy induction for acute myelogenous leukemia.

Human herpesvirus-6 encephalitis following chemotherapy induction for acute myelogenous leukemia.
Author Information (click to view)

Frey JW, Cherabie JN, Assi MA,


Frey JW, Cherabie JN, Assi MA, (click to view)

Frey JW, Cherabie JN, Assi MA,

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Transplant infectious disease : an official journal of the Transplantation Society 2017 07 26() doi 10.1111/tid.12756

Abstract

We report a case of human herpesvirus-6 (HHV-6) encephalitis in a neutropenic patient who had undergone chemotherapy induction for acute myelogenous leukemia while on broad-spectrum antimicrobial therapy. The patient displayed symptoms of confusion, amnesia, and lethargy. Diagnosis was made via polymerase chain reaction analysis of cerebrospinal fluid. Electroencephalogram and magnetic resonance imaging of the brain were unremarkable. Following diagnosis, the patient was successfully treated with ganciclovir. HHV-6 encephalitis should be considered in immunocompromised patients who become encephalopathic. This article is protected by copyright. All rights reserved.

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