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Human pegivirus (HPgV) infection in sub-Saharan Africa-A call for a renewed research agenda.

Human pegivirus (HPgV) infection in sub-Saharan Africa-A call for a renewed research agenda.
Author Information (click to view)

Singh S, Blackard JT,


Singh S, Blackard JT, (click to view)

Singh S, Blackard JT,

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Reviews in medical virology 2017 11 17() doi 10.1002/rmv.1951

Abstract

The human pegivirus (HPgV)-formerly GB virus C-has a beneficial impact on HIV disease progression that has been described in multiple studies. Given the high prevalence of HIV in sub-Saharan Africa and the continuing need to suppress HIV replication, this review provides a comprehensive overview of the existing data on HPgV infection in sub-Saharan Africa, with a particular focus on studies of prevalence and the circulating HPgV genotypes. This review also highlights the need for additional studies of HPgV conducted on the African continent and proposes a research agenda for evaluation of HPgV.

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