Abnormal regulation of airway surface hydration appears to slow mucociliary clearance in chronic bronchitis and contributes to the disease pathogenesis, according to researchers in North Carolina. Investigators found that increased mucus concentration was associated with decreased mucociliary clearance.

Source: American Journal of Respiratory and Critical Care Medicine, April 24, 2015 (online).

An abstract of the study is available at www.atsjournals.org/doi/abs/10.1164/rccm.201412-2230OC#.VVIO4_lVhBc.