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Hypertension treatment practices and its determinants among ambulatory patients: retrospective cohort study in Ethiopia.

Hypertension treatment practices and its determinants among ambulatory patients: retrospective cohort study in Ethiopia.
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Berhe DF, Taxis K, Haaijer-Ruskamp FM, Mulugeta A, Mengistu YT, Mol PGM,


Berhe DF, Taxis K, Haaijer-Ruskamp FM, Mulugeta A, Mengistu YT, Mol PGM, (click to view)

Berhe DF, Taxis K, Haaijer-Ruskamp FM, Mulugeta A, Mengistu YT, Mol PGM,

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BMJ open 2017 08 037(8) e015743 doi 10.1136/bmjopen-2016-015743
Abstract
OBJECTIVES
We examined determinants of achieving blood pressure control in patients with hypertension and of treatment intensification in patients with uncontrolled blood pressure (BP).

DESIGN
A retrospective cohort study in six public hospitals, Ethiopia.

PARTICIPANTS
Adult ambulatory patients with hypertension and with at least one previously prescribed antihypertensive medication in the study hospital.

OUTCOME
Controlled BP (<140/90 mm Hg) and treatment intensification of patients with uncontrolled BP. RESULTS
The study population comprised 897 patients. Their mean age was 57 (SD 14) years, 63% were females, and 35% had one or more cardiometabolic comorbidities mainly diabetes mellitus. BP was controlled in 37% of patients. Treatment was intensified for 23% patients with uncontrolled BP. In multivariable (logistic regression) analysis, determinants positively associated with controlled BP were treatment at general hospitals (OR 1.89, 95% CI 1.26 to 2.83) compared with specialised hospitals and longer treatment duration (OR 1.04, 95% CI 1.01 to 1.06). Negatively associated determinants were previously uncontrolled BP (OR 0.30, 95% CI 0.21 to 0.43), treatment regimens with diuretics (OR 0.68, 95% CI 0.50 to 0.94) and age (OR 0.99, 95% CI 0.98 to 1.00). The only significant-positive-determinant for treatment intensification was duration of therapy (OR 1.05, 95% CI 1.02 to 1.09).

CONCLUSIONS
The level of controlled BP and treatment intensification practice in this study was low. The findings suggest the need for in-depth understanding and interventions of the identified determinants such as uncontrolled BP on consecutive visits, older age and type of hospital.

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