The Particulars: Data are lacking on the burden of Clostridium difficile infection (CDI) recurrence.
Data Breakdown: For a study, investigators used a long-term, large sample database and a matching algorithm to adjust for the confounding effect of patient baseline characteristics and comorbidities. The clinical outcomes and healthcare resource use of patients with a single CDI episode were compared with those of patients with recurrent infection from 2001 to 2010. The study team observed the following:
|Patients with recurrent CDI||Patients with non-recurrent CDI|
|ED visits per year||1.7 visits||1.3 visits|
|Days of overnight hospitalization||9.7 days||5.7 days|
|ICU days||1.1 days||0.6 days|
Take Home Pearls: Recurrent CDI appears to be associated with worse patient outcomes and a greater burden of resource use when compared with non-recurrent CDI. Identifying patients at increased risk for recurrence and preventing such recurrences is crucial to averting serious CDI-related complications.