For a study, researchers sought to work on clinical practice regarding the conclusion of idiopathic myointimal hyperplasia of the mesenteric veins. It was a review observational review. The study was led in a solitary organization with a case assortment from clinical chronicles. Information from 12 instances of idiopathic myointimal hyperplasia of the mesenteric veins was recovered from 2006-2020. Most patients were older men, with a male-to-female proportion of 10:1. Clinical, endoscopic, radiologic, and pathologic qualities of idiopathic myointimal hyperplasia of the mesenteric veins filled in as result measures. Radiologically, marked segmental painting thickening and an unfortunate upgrade included the sigmoid colon and rectum by and large, with expansion to the diving colon at times. Commonplace cases showed decimation of the sub-par mesenteric veins and collateral vessels. Colonoscopic discoveries suggest ischemia or ulcerative colitis; however, sharp division from the uninvolved section was the most distinctive element. Carefully resected examples showed checked segmental wall painting thickening, edema, and mucosal staining terribly. Minutely, thick-walled, convoluted veins were noticed in the submucosa and subserosa, and the submucosa was extraordinarily thickened in all cases. The huge subserosal veins showed minimal hyperplasia, and pericolic fat putrefaction was perpetually noticed. The most helpful histologic finding in biopsy material was convoluted, arterialized mucosal vessels with periodic fibrinoid rot. The study was restricted by its modest number of cases and choice inclination; there was likewise no forthcoming outside approval. Radiologic and pathologic elements of idiopathic myointimal hyperplasia of the mesenteric veins were unmistakable from those of ulcerative colitis or reminiscent ischemic colitis. Cautious translation of endoscopic and radiologic pictures and liberal biopsies with understanding by experienced pathologists could prompt an early conclusion and forestall superfluous clinical treatment.