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Immediately Functioning Grafts from Brain-Dead Donors Treated with Extracorporeal Membrane Oxygenation.

Immediately Functioning Grafts from Brain-Dead Donors Treated with Extracorporeal Membrane Oxygenation.
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Shaheen FA, Shalabi M, Zain A, Hasanain M, Al Sayyari A,


Shaheen FA, Shalabi M, Zain A, Hasanain M, Al Sayyari A, (click to view)

Shaheen FA, Shalabi M, Zain A, Hasanain M, Al Sayyari A,

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Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 2017 02 23() doi 10.6002/ect.2016.0369
Abstract

A brain-dead donor experienced repeated cardiac arrests followed by severe hypotension requiring multiple vasoactive agents. These events were associated with severe lactic acidosis and dysregulated kidney function in the donor. A 10-hour treatment with extracorporeal membranous oxygenation was instituted, which was able to hemodynamically stabilize the donor. This treatment protocol resulted in the procurement of 2 viable kidney grafts transplanted into 2 recipients, who had immediate kidney graft function and excellent serum creatinine levels upon hospital discharge. These results are all the more significant considering that both cases involved long cold ischemia times, and one of the recipients had diabetes and was receiving his second kidney graft.

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