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Impaired patient-reported outcomes persist in HIV-HCV co-infected patients and in cirrhotic patients despite HCV clearance.

Impaired patient-reported outcomes persist in HIV-HCV co-infected patients and in cirrhotic patients despite HCV clearance.
Author Information (click to view)

Marcellin F, Morlat P, Wittkop L, Salmon-Ceron D, Carrieri MP,


Marcellin F, Morlat P, Wittkop L, Salmon-Ceron D, Carrieri MP, (click to view)

Marcellin F, Morlat P, Wittkop L, Salmon-Ceron D, Carrieri MP,

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Journal of viral hepatitis 2017 10 27() doi 10.1111/jvh.12811

Abstract

Dirks et al.(1) ‘s recent study provides greater insight into the neuropsychiatric symptoms experienced by HCV infected patients and questions how these symptoms are associated with HCV clearance. The authors show that in HCV infected patients with mild liver disease, none of the following outcomes depend on HCV clearance: cognitive function, mood alteration, health-related quality of life (HRQL) and fatigue (FIS scores). However, these results may not be generalizable to HIV-HCV co-infected patients and cirrhotic patients, who were excluded from the study and who are generally more concerned by fatigue and neuropsychiatric symptoms. This article is protected by copyright. All rights reserved.

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