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Increased maximum common carotid intima-media thickness is associated with smoking and hypertension in Tochigi Prefecture residents.

Increased maximum common carotid intima-media thickness is associated with smoking and hypertension in Tochigi Prefecture residents.
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Iwasaki A, Takekawa H, Okabe R, Suzuki K, Okamura M, Nishihira T, Suzuki A, Tsukahara Y, Hirata K,


Iwasaki A, Takekawa H, Okabe R, Suzuki K, Okamura M, Nishihira T, Suzuki A, Tsukahara Y, Hirata K, (click to view)

Iwasaki A, Takekawa H, Okabe R, Suzuki K, Okamura M, Nishihira T, Suzuki A, Tsukahara Y, Hirata K,

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Journal of medical ultrasonics (2001) 2017 02 15() doi 10.1007/s10396-017-0774-9
Abstract
OBJECTIVE
We investigated maximum intima-media thickness of the common carotid artery (IMT-Cmax) in residents of Tochigi Prefecture, who have been reported to have high stroke mortality.

METHOD
Our study included 840 individuals. All participants underwent carotid ultrasonography and answered a questionnaire during participation in a health festival in Tochigi Prefecture. The questionnaire was designed to collect information on age, gender, and risk factors for stroke. IMT-Cmax was measured. Statistical analyses were performed to identify factors contributing to IMT-Cmax values ≥1.1 mm.

RESULTS
In total, 117 subjects had an IMT-Cmax value ≥1.1 mm. IMT-Cmax correlated significantly with age, current smoking, hypertension, diabetes mellitus, heart disease, and previous symptomatic stroke (p < 0.05) in univariate analysis. Current smoking (p < 0.001, odds ratio 3.88) and hypertension (p = 0.0070, odds ratio 1.83) were seen as significant contributing factors to IMT-Cmax ≥1.1 mm in logistic regression analysis adjusted by age, gender, and previous symptomatic stroke. CONCLUSION
We identified current smoking and hypertension as the most significant contributing factors to increased IMT-Cmax in residents of Tochigi Prefecture, emphasizing the importance of routine blood pressure monitoring and anti-smoking education in this population.

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