The aim of this review is to understand how Nannizziopsis spp. are portrayed as keratinophilic ascomycetous organisms that cause dermal diseases with every now and again lethal results in different reptiles (e.g., reptiles, geckos, chameleons, iguanas, snakes, and crocodiles), predominantly in bondage (1,2). Nannizziopsis spp. have a place with the request for Onygenales and the as of late portrayed group of Nannizziopsidaceae (1). In people, obtrusive Nannizziopsis spp. disease appears to be uncommon; just 5 cases have been accounted for to date (1,3–7). Such a perception recommends a real extraordinariness, a new rise in view of alteration in the ecoepidemiology (e.g., new populaces in danger [8]), or past underdiagnoses or misdiagnoses due to an absence of positive recognizable proof.

We depict 9 human instances of intrusive parasitic contamination with N. obscura species complex distinguished in France during 2004–2020 (Table 1), alongside the underlying recognizable proof from the 5 revealing medical clinics. Detaches were shipped off France’s National Reference Center for Invasive Mycoses and Antifungals, where a polyphasic distinguishing proof joining phenotypic highlights and atomic information was performed. Seven of the 9 cases were analyzed after 2016.

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