The family history has unknown impact on children with irritable bowel syndrome (IBS). A retrospective study was carried out to compare between children with family history of IBS (FH-IBS) and non-clinically profiled and management differences. The study comprised a total of 251 children, 75 (30%) did not have the FH-IBS and 176 (70%). The 2 compositional groups, age at first visit, age of IBS diagnosis, dietary alterations, supplements, laxative products, antispasmodic, anti diarrhea and cyproheptadine were found to have no significant differences.

Children with IBS were however more likely to receive psychological counselling (41% versus 23%, P = 0,003), and antidepressants (36% compared 15%, P < 0,001) against children without IBS. FH-ISDI children were nevertheless more likely to receive psychological therapy (49% versus 23%, P < 0,001). We found that the psychological illnesses underlie children with FH-IBS, and that psycho-intervention are more likely to occur.

Reference: https://journals.lww.com/jpgn/Abstract/2021/06000/Influence_of_Family_History_on_Children_With.16.aspx