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Interactions of Cryptococcus with Dendritic Cells.

Interactions of Cryptococcus with Dendritic Cells.
Author Information (click to view)

Wozniak KL,


Wozniak KL, (click to view)

Wozniak KL,

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Journal of fungi (Basel, Switzerland) 2018 03 154(1) pii E36
Abstract

The fungal pathogensandcan cause life-threatening infections in immune compromised and immune competent hosts. These pathogens enter the host via inhalation, and respiratory tract innate immune cells such as dendritic cells (DCs) are one of the first host cells they encounter. The interactions betweenand innate immune cells play a critical role in the progression of disease in the host. This review will focus specifically on the interactions betweenand dendritic cells (DCs), including recognition/processing by DCs, effects of immune mediators on DC recruitment and activity, and the potential for DC vaccination against cryptococcosis.

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