For a study, researchers sought to understand that for benign pigmented lesions, a noninvasive therapeutic strategy was to target melanin using intense pulsed light (IPL). The study looked into the use of IPL as a viable treatment for benign pigmented lesions on the dorsal hands. About 15 individuals between the ages of 40 and 73 received 3 monthly IPL treatments over their dorsal hands. About 1 and 3 months after completing therapy, the patients received follow-up visits. The VISIA Complexion Analysis System (Canfield Scientific, Fairfield, NJ) was used to acquire photos at each visit, and the RBX Brown Spots Analysis method was used to analyze the data. At both follow-up appointments, the Subject Global Aesthetic Improvement Scale and the Clinician Global Aesthetic Improvement Scale were filled out. All 6 appointments were completed by a total of 15 people. The percentage of brown patches decreased by 9.26% (P=.0004) and 7.52% (P=.0132) on each subsequent visit. At 1 and 3 months after starting therapy, the mean brown intensity fell by 6.15% (P=.00183) and 7.67% (P=.0078), respectively, whereas the mean contrast intensity reduced by 8.8 % (P<.0001) and 6.6% (P=.0007). Around 1 and 3 months after treatment, the mean Subject Global Aesthetic Improvement Scale was 1.6 and 1.8, whereas the mean Clinician Global Aesthetic Improvement Scale was 2.03 and 2.23. Clinical evaluations, subject evaluations, and objective analyses all revealed that the appearance of benign pigmented lesions in the treated area had improved after 3 IPL sessions.

Source: journals.lww.com/dermatologicsurgery/Abstract/2022/08000/The_Efficacy_of_Intense_Pulsed_Light_as_a.6.aspx