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Is matrix stiffness a cause for malignant transformation of OSF?

Is matrix stiffness a cause for malignant transformation of OSF?
Author Information (click to view)

Choudhari SS, Kulkarni DG, Sarode SC, Kheur SM, Patankar S,


Choudhari SS, Kulkarni DG, Sarode SC, Kheur SM, Patankar S, (click to view)

Choudhari SS, Kulkarni DG, Sarode SC, Kheur SM, Patankar S,

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Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2018 04 14() doi 10.1111/jop.12714
Abstract

Fibrosis is a pathological process characterized by mesenchymal cell infiltration and proliferation in the interstitial space, which occurs in order to repair epithelial injuries leading to the formation of granulation tissue. [1] The relationship between fibrosis and the development of carcinoma was described for the first time by Friedrich in 1939. [2] Since then, multiple studies have been attempted to determine the relationship between fibrosis and development of malignancy. This article is protected by copyright. All rights reserved.

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