REAH is a benign lesion of the sinonasal tract that may mimic more concerning pathology. Clinical factors associated with REAH have not been well characterized.

This study was done to report our findings on patients with this pathological diagnosis.

A retrospective chart review of patients with REAH was conducted. Data collected included clinical allergic rhinitis and asthma history, additional sinonasal diagnoses, prior sinus surgery, and the location of the REAH within the sinonasal cavity.

26 patients were identified. Bilateral REAH occurred in 50%. Concurrent sinonasal inflammatory disorders were identified in 18 patients, including chronic rhinosinusitis with nasal polyps—not otherwise specified, chronic rhinosinusitis without nasal polyps, aspirin-exacerbated respiratory disease, allergic fungal rhinosinusitis, central compartment atopic disease, and IgG4-related sclerosing disease. Eight patients had isolated REAH. Adequate allergy records were available for 19 patients, of which 18 of 19 had clinical allergic rhinitis.

The study concluded through its findings that the REAH is a benign sinonasal lesion commonly located within the central compartment of the nasal cavity, a site of significant allergen exposure. Affected patients have a high incidence of allergy along with chronic inflammatory conditions.

Reference: https://journals.sagepub.com/doi/full/10.1177/1945892420914212