Here are what the editors at HealthDay consider to be the most important developments in Hematology & Oncology for January 2020. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Reirradiation Rarely Required in Focal RT for Multiple Myeloma

FRIDAY, Jan. 31, 2020 (HealthDay News) — For patients with multiple myeloma receiving focal radiation therapy (RT) for symptomatic plasmacytoma, reirradiation is rarely required, according to a letter to the editor published online Jan. 9 in Haematologica.

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2017 to 2018 Saw Increase in Life Expectancy in the United States

THURSDAY, Jan. 30, 2020 (HealthDay News) — From 2017 to 2018, there was an increase in life expectancy in the United States and a decrease in age-adjusted death rates, according to a January data brief published by the U.S. Centers for Disease Control and Prevention National Center for Health Statistics.

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Nitrite Consumption May Up Risk for Non-Hodgkin Lymphoma

THURSDAY, Jan. 30, 2020 (HealthDay News) — Nitrite consumption is associated with an increased risk for non-Hodgkin lymphoma (NHL), according to a meta-analysis published online Jan. 17 in Scientific Reports.

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U.S. Spends More on Health Care, but Has Worse Life Expectancy

THURSDAY, Jan. 30, 2020 (HealthDay News) — The United States spends substantially more than any other wealthy nation on health care, yet it has a lower life expectancy and a higher suicide rate than other wealthy nations, according to a January data brief released by the Commonwealth Fund.

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Social Support Linked to Mortality in Older Women With CRC

THURSDAY, Jan. 30, 2020 (HealthDay News) — For postmenopausal women with colorectal cancer (CRC), low social support is associated with elevated overall and CRC-specific mortality, according to a study published online Jan. 23 in Cancer.

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Volume CT Screening Cuts Lung Cancer Mortality at 10 Years

WEDNESDAY, Jan. 29, 2020 (HealthDay News) — Volume computed tomography (CT) screening results in significantly lower lung cancer mortality at 10 years, according to a study published online Jan. 29 in the New England Journal of Medicine.

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Benefits of Psilocybin-Assisted Psychotherapy May Be Lasting

WEDNESDAY, Jan. 29, 2020 (HealthDay News) — Psilocybin-assisted psychotherapy may promote long-term benefits in terms of reductions in anxiety, depression, and hopelessness among patients with cancer-related psychiatric distress, according to a study published online Jan. 9 in the Journal of Psychopharmacology.

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Gender Gap Persists in Starting Salary for Physicians

TUESDAY, Jan. 28, 2020 (HealthDay News) — The gender gap in starting salary for physicians persists, although it is unclear which factors account for this gap, according to a report published online Jan. 22 in Health Affairs.

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Wealthy Pay Most to Finance U.S. Health Care

MONDAY, Jan. 27, 2020 (HealthDay News) — Health care payments in the United States are more regressive than previously thought, according to a study published online Jan. 27 in Health Services Research.

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Outcomes No Worse for Black Veterans With Prostate Cancer

MONDAY, Jan. 27, 2020 (HealthDay News) — For men diagnosed with prostate cancer in the Veterans Affairs health system, African-Americans (AAs) do not present with more advanced disease or have worse outcomes compared with non-Hispanic whites (NHWs), according to a study published online Jan. 27 in Cancer.

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Updated Guidelines Issued for ER, PgR Testing in Breast Cancer

MONDAY, Jan. 27, 2020 (HealthDay News) — In an American Society of Clinical Oncology/College of American Pathologists updated guideline, published online Jan. 13 in the Archives of Pathology & Laboratory Medicine and the Journal of Clinical Oncology, recommendations are presented for estrogen and progesterone receptor (ER/PgR) testing in breast cancer.

Abstract/Full Text – Archives of Pathology & Laboratory Medicine
Abstract/Full Text – Journal of Clinical Oncology

Nearly Half of U.S. Smokers Not Advised by Doctors to Quit

FRIDAY, Jan. 24, 2020 (HealthDay News) — Too few American smokers are advised by their doctors to quit, according to a report released Thursday by U.S. Surgeon General Jerome Adams, M.D.

The New York Times Article
Office of the Surgeon General

High-Dose IV Vitamin C Does Not Speed Resolution of Septic Shock

FRIDAY, Jan. 24, 2020 (HealthDay News) — Treatment with intravenous vitamin C, hydrocortisone, and thiamine does not improve the duration of time alive and vasopressor administration-free compared with intravenous hydrocortisone alone among patients with septic shock, according to a study published online Jan. 17 in the Journal of the American Medical Association.

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Editorial

Major Insurers Offer $55 Million to Lower Generic Drug Costs

THURSDAY, Jan. 23, 2020 (HealthDay News) — A nonprofit that develops and sells cheaper drugs will receive a $55 million investment from the Blue Cross Blue Shield Association and associated organizations to create cheaper versions of expensive generic drugs.

The New York Times Article

JumpstartMD Commercial Program Seems Effective for Weight Loss

THURSDAY, Jan. 23, 2020 (HealthDay News) — The commercial low-calorie, low-carbohydrate JumpstartMD program is effective for weight loss, according to a study published online Jan. 21 in the Journal of Obesity.

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Fewer Than Half of Clinical Trials Comply With Reporting Laws

THURSDAY, Jan. 23, 2020 (HealthDay News) — Compliance with the U.S. Food and Drug Administration Amendments Act of 2007 is low, with only 40.9 percent of trials reporting results within one year, according to a study published online Jan. 17 in The Lancet.

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Fast-Track Review of ACA Lawsuit Rejected by U.S. Supreme Court

WEDNESDAY, Jan. 22, 2020 (HealthDay News) — A fast-track review of a lawsuit that threatens the Affordable Care Act was rejected Tuesday by the U.S. Supreme Court.

AP News Article

ACP: Medicare for All Needed to Fix ‘Ill’ U.S. Health Care System

TUESDAY, Jan. 21, 2020 (HealthDay News) — The American College of Physicians (ACP) says the U.S. health care system “is ill and needs a bold new prescription” that includes coverage for all Americans and lower costs.

AP News Article
American College of Physicians

Intensity-Modulated Radiation Charges for Prostate Cancer Vary

TUESDAY, Jan. 21, 2020 (HealthDay News) — There is considerable variation in listed charges for simple intensity-modulated radiation therapy used in prostate cancer treatment, with a weak positive association for price and geographic practice cost index, according to a study published online Jan. 16 in JAMA Oncology.

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Dasatinib Tops Imatinib for Ph+ Acute Lymphoblastic Leukemia

TUESDAY, Jan. 21, 2020 (HealthDay News) — Dasatinib is associated with improved survival for pediatric patients with Philadelphia chromosome-positive acute lymphoblastic leukemia (ALL), according to a study published online Jan. 16 in JAMA Oncology.

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Further Improvements in Survival Seen After Allogeneic Transplant

TUESDAY, Jan. 21, 2020 (HealthDay News) — From 2003-2007 to 2013-2017, there was an improvement in survival for allogeneic hematopoietic cell transplantation, according to a study published online Jan. 21 in the Annals of Internal Medicine.

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Medical Cannabis May Initially Aid Sleep in Chronic Pain Patients

TUESDAY, Jan. 21, 2020 (HealthDay News) — For patients with chronic pain, medical cannabis (MC) use has a positive effect on maintaining sleep; however, cannabinoids do not appear to reduce cancer pain, according to a study and review published online Jan. 20 in BMJ Supportive & Palliative Care.

Abstract/Full Text – Sznitman
Abstract/Full Text – Boland

Cancer Survivors Have Substantial Medical Financial Hardship

FRIDAY, Jan. 17, 2020 (HealthDay News) — Many cancer survivors have substantial medical financial hardship and make financial sacrifices, according to a study published online Jan. 15 in Cancer Epidemiology, Biomarkers & Prevention.

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Decline in Mortality Seen in Diabetes Patients in Hong Kong

FRIDAY, Jan. 17, 2020 (HealthDay News) — From 2001 to 2016, mortality declined among people with diabetes in Hong Kong, according to a study published online Jan. 16 in Diabetologia.

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Colorectal Cancer Risk Still Up in Patients With Ulcerative Colitis

FRIDAY, Jan. 17, 2020 (HealthDay News) — Patients with ulcerative colitis have an increased risk for colorectal cancer and colorectal cancer mortality, according to a study published in the Jan. 11 issue of The Lancet.

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Lack of Self-Exams Hampers Early Melanoma Identification

FRIDAY, Jan. 17, 2020 (HealthDay News) — The biggest obstacle to early detection and treatment of melanoma among residents of rural, frontier communities is a chronic lack of skin self-examination (SSE), according to a study recently published in Psychology, Health & Medicine.

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Single-Payer System Would Likely Save Money

THURSDAY, Jan. 16, 2020 (HealthDay News) — There is near consensus across 30 years of economic analysis of single-payer plans that a single-payer system would reduce health expenditures in the United States, according to a review published online Jan. 15 in PLOS Medicine.

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CDC: Many Americans Are Inactive, With Southerners Faring Worse

THURSDAY, Jan. 16, 2020 (HealthDay News) — More than 15 percent of American adults are physically inactive, according to a new U.S. Centers for Disease Control and Prevention study.

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Sepsis Associated With Almost 20 Percent of Global Deaths

THURSDAY, Jan. 16, 2020 (HealthDay News) — From 1990 to 2017, there was a decrease in sepsis incidence and mortality, although considerable regional variation exists, according to a study published online Jan. 16 in The Lancet.

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Coronary Artery Disease Risk Down in Survivors of Childhood Cancer

THURSDAY, Jan. 16, 2020 (HealthDay News) — There has been a decrease in the risk for coronary artery disease among adult survivors of childhood cancer, according to a study published online Jan. 15 in The BMJ.

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Editorial

Ageism Predicts Significantly Worse Health Outcomes

THURSDAY, Jan. 16, 2020 (HealthDay News) — Ageism predicts significantly worse health outcomes, according to a review published online Jan. 15 in PLOS ONE.

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Satisfaction High With Mohs Surgery for Melanoma In Situ

THURSDAY, Jan. 16, 2020 (HealthDay News) — Patients are very satisfied with Mohs micrographic surgery (MMS) for melanoma in situ, according to a research letter recently published in Dermatologic Surgery.

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Increasing Vegetable Intake Does Not Slow Prostate Cancer

THURSDAY, Jan. 16, 2020 (HealthDay News) — A behavioral intervention that increases vegetable consumption does not reduce the risk for progression of early-stage prostate cancer, according to a study published in the Jan. 14 issue of the Journal of the American Medical Association.

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Lack of Insurance Tied to Later Stage of Breast Cancer at Diagnosis

THURSDAY, Jan. 16, 2020 (HealthDay News) — Insurance status and access to care play an important role in racial disparities in stage of breast cancer at diagnosis, according to a study published online Jan. 9 in JAMA Oncology.

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ACA Tied to Narrowing of Disparities in Access to Care

THURSDAY, Jan. 16, 2020 (HealthDay News) — The Affordable Care Act has reduced disparities in access to health care among black, Hispanic, and white adults, according to a January data brief released by the Commonwealth Fund.

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FDA: Weight Control Drug Lorcaserin May Raise Cancer Risk

WEDNESDAY, Jan. 15, 2020 (HealthDay News) — The prescription weight control medicine lorcaserin (Belviq, Belviq XR) may increase the risk for cancer, according to the results of a clinical trial assessing the safety of the drug, the U.S. Food and Drug Administration says.

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AI System Can Detect, Grade Cancer in Prostate Needle Biopsy

WEDNESDAY, Jan. 15, 2020 (HealthDay News) — An artificial intelligence (AI) system can be used to detect and grade prostate cancer in prostate needle biopsy samples, according to a study published online Jan. 8 in The Lancet Oncology.

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Evolution of Approval, Regulation Processes for Drugs Explored

WEDNESDAY, Jan. 15, 2020 (HealthDay News) — The U.S. approval and regulation processes for pharmaceutical agents have evolved during the last four decades, according to a study published in the Jan. 14 issue of the Journal of the American Medical Association.

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Nonalcoholic Steatohepatitis Will Pose Clinical, Economic Burden

TUESDAY, Jan. 14, 2020 (HealthDay News) — Nonalcoholic steatohepatitis (NASH) is expected to pose a significant clinical and economic burden during the next 20 years for U.S. patients with type 2 diabetes mellitus (T2DM), according to a study published online Jan. 6 in Diabetes Care.

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Notification Laws May Not Increase Knowledge of Dense Breast Risks

TUESDAY, Jan. 14, 2020 (HealthDay News) — State dense-breast notification (DBN) laws are not associated with increased understanding of the clinical implications of breast density, according to a study published online Jan. 8 in the Journal of General Internal Medicine.

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Alcohol Consumption Levels High in Cancer Patients, Survivors

TUESDAY, Jan. 14, 2020 (HealthDay News) — More than one-third of cancer patients report exceeding moderate drinking levels, according to a study published in the January issue of the Journal of the National Comprehensive Cancer Network.

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Doctor Replacement Ratios Higher in Largest, Hospital-Owned Practices

TUESDAY, Jan. 14, 2020 (HealthDay News) — From 2009 to 2016, more physicians entering the Medicare program worked at large group or hospital-owned practices than small group or independent practices, according to a research letter published online Jan. 14 in the Annals of Internal Medicine.

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Cancer Incidence Up in World Trade Center Responder Cohort

TUESDAY, Jan. 14, 2020 (HealthDay News) — Cancer incidence is increased in the World Trade Center (WTC) Health Program General Cohort, according to a study published in the February issue of JNCI Cancer Spectrum.

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Vaccine Program Recovery Difficult After Public Scares

TUESDAY, Jan. 14, 2020 (HealthDay News) — Misinformation in the Danish media between 2013 and 2016 led to a 50.4 percent drop in human papillomavirus (HPV) vaccinations among girls in Denmark, according to a study published online Jan. 7 in Vaccine.

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Physicians Spend >16 Minutes Per Encounter on EHR Use

MONDAY, Jan. 13, 2020 (HealthDay News) — Physicians spend a considerable amount of time using electronic health records (EHRs) to support care delivery, with wide variation seen in the distribution of time within specialty, according to a study published online Jan. 14 in the Annals of Internal Medicine.

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NFL Joins Blood Drive by Giving Away Two Super Bowl Tickets

MONDAY, Jan 13, 2020 (HealthDay News) — The American Red Cross has an urgent need for all blood types, but especially for type O.

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Mortality Risk in Oropharynx Cancer Varies Based on HPV Status

MONDAY, Jan. 13, 2020 (HealthDay News) — For patients with oropharynx cancer, the rates of head and neck cancer (HNC) mortality and competing mortality vary depending on human papillomavirus (HPV) status, with increased risks for HNC mortality and competing mortality in HPV-negative patients, according to a study published online Jan. 13 in Cancer.

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Guidance Issued for Hepatic, Mesenteric Circulation Disorders

MONDAY, Jan. 13, 2020 (HealthDay News) — In a clinical guideline from the American College of Gastroenterology, published in the January issue of the American Journal of Gastroenterology, recommendations are presented for management of disorders of the hepatic and mesenteric circulation.

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Burnout in Med Students Tied to Perceived Stress, Phone Behavior

MONDAY, Jan. 13, 2020 (HealthDay News) — Higher levels of perceived stress, poorer sleep quality, and smartphone addiction contribute to burnout in osteopathic medical students, according to a study published in the January issue of the Journal of the American Osteopathic Association.

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Incidental Lymphopenia Linked to Increased Risk for Mortality

MONDAY, Jan. 13, 2020 (HealthDay News) — Incidental lymphopenia is associated with an increased risk for all-cause and cause-specific mortality, according to a study published in the Jan. 13 issue of CMAJ, the journal of the Canadian Medical Association.

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California May Start Producing Its Own Medicines

FRIDAY, Jan. 10, 2020 (HealthDay News) — A proposal for California to contract generic drug companies to make medications would make the state the first in the country to produce its own medications.

AP News Article

Neighborhood Disadvantage Impacts Hospital Quality Ratings

FRIDAY, Jan. 10, 2020 (HealthDay News) — Hospitals caring for neighborhoods with high levels of disadvantage may have lower hospital ratings due to social risk factors (SRFs) in the community, according to a study published online Dec. 30 in Medical Care.

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Recruitment Satisfactory for Foreign-Educated Health Providers

FRIDAY, Jan. 10, 2020 (HealthDay News) — Foreign-educated health professionals (FEHPs) in the United States are overall satisfied with their recruitment experience, according to a study published in the January issue of the American Journal of Nursing.

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Metabolic Syndrome May Up Risk for VTE Recurrence After DVT

THURSDAY, Jan. 9, 2020 (HealthDay News) — For patients with deep vein thrombosis (DVT), the presence of any component of metabolic syndrome (MetS) is independently associated with an increased risk for venous thromboembolism (VTE) recurrence, according to a study published online Jan. 9 in Blood Advances.

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Clinical Guidelines Developed for Managing Nosebleeds

THURSDAY, Jan. 9, 2020 (HealthDay News) — In a clinical practice guideline from the American Academy of Otolaryngology-Head and Neck Surgery Foundation, published online Jan. 7 in Otolaryngology-Head and Neck Surgery, recommendations are presented for the management of nosebleeds.

Clinical Practice Guideline
Executive Summary

Life Expectancy Free of Chronic Disease Up With Healthy Lifestyle

THURSDAY, Jan. 9, 2020 (HealthDay News) — Adherence to a healthy lifestyle at midlife is associated with increased life expectancy free of major chronic diseases, according to a study published online Jan. 8 in The BMJ.

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Perceived Risks of E-Cigarettes Vary With Demographics

THURSDAY, Jan. 9, 2020 (HealthDay News) — For youth, the perceived risks of electronic cigarette products vary with demographics, sexual orientation, and socioeconomic status, according to a study published online Jan. 7 in Health Promotion Practice.

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Untreated Oral Infection Not Tied to Stem Cell Transplant Outcomes

THURSDAY, Jan. 9, 2020 (HealthDay News) — Untreated chronic oral infection is not associated with post-hematopoietic stem cell transplant (HSCT) outcomes, according to a study published online Dec. 18 in PLOS ONE.

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Large Gap Found in Health Administrative Spending for U.S., Canada

WEDNESDAY, Jan. 8, 2020 (HealthDay News) — There is a large and widening gap in health administrative spending between the United States and Canada, according to a study published online Jan. 7 in the Annals of Internal Medicine.

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Luspatercept Mitigates Anemia in Lower-Risk Myelodysplastic Syndromes

WEDNESDAY, Jan. 8, 2020 (HealthDay News) — For patients with lower-risk myelodysplastic syndromes with ring sideroblasts who have been receiving regular red-cell transfusions, luspatercept reduces the severity of anemia compared with placebo, according to a study published in the Jan. 9 issue of the New England Journal of Medicine.

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Cancer Mortality Continuing to Drop, With Lung Cancer a Driver

WEDNESDAY, Jan. 8, 2020 (HealthDay News) — Cancer mortality is continuing to decline, driven by progress in lung cancer, although mortality reductions have slowed or stopped for some cancers, according to findings included in Cancer Statistics, 2020, the American Cancer Society’s latest annual report on cancer incidence, mortality, and survival. The report was published online Jan. 8 in CA: A Cancer Journal for Clinicians.

Cancer Statistics, 2020

CDC: Young Adults Who Ever Received HPV Vaccine on the Rise

TUESDAY, Jan. 7, 2020 (HealthDay News) — From 2013 to 2018, there was an increase in the percentage of adults aged 18 to 26 years who received one or more doses or the recommended number of doses of human papillomavirus (HPV) vaccine, according to a January data brief published by the U.S. Centers for Disease Control and Prevention National Center for Health Statistics.

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Use of Powder in Genital Area Not Linked to Ovarian Cancer

TUESDAY, Jan. 7, 2020 (HealthDay News) — Use of powder in the genital area does not appear to be significantly associated with incident ovarian cancer, according to a study published in the Jan. 7 issue of the Journal of the American Medical Association.

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Risk for Blood Clots Increased With PICC Placement in Children

TUESDAY, Jan. 7, 2020 (HealthDay News) — Central venous catheter (CVC) placement with peripherally inserted central catheters (PICCs) in children is associated with increased risks for venous thromboembolism (VTE), central line-associated bloodstream infection (CLABSI), and CVC malfunction, according to a study published online Jan. 7 in Blood.

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Laser-Based Imaging + AI May Diagnose Brain Tumors in OR

MONDAY, Jan. 6, 2020 (HealthDay News) — A novel workflow that combines advanced optical imaging with an artificial intelligence algorithm may accurately diagnose brain tumors in real time in the operating room, according to a study published online Jan. 6 in Nature Medicine.

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Price Hikes for Hundreds of Medications

MONDAY, Jan. 6, 2020 (HealthDay News) — U.S. drug companies have started the new year by raising the prices of hundreds of medications.

CBS News Article

More Education Needed on Breast Density and Screening Choices

MONDAY, Jan. 6, 2020 (HealthDay News) — Being a resident in a state with a dense breast notification law does not appear to help women know more about breast density, according to a study published online Dec. 2 in the Journal of General Internal Medicine.

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Poll: Older Adults Frequently Use Online Physician Ratings

MONDAY, Jan. 6, 2020 (HealthDay News) — Older adults commonly use online ratings to choose a doctor, according to a report published online Jan. 6 based on the results of the University of Michigan National Poll on Healthy Aging.

National Poll on Healthy Aging

One-Cycle BE500P Seems Safe for High-Risk Early Testicular Cancer

MONDAY, Jan. 6, 2020 (HealthDay News) — For high-risk stage 1 nonseminoma germ cell tumors of the testis (NSGCTT), one cycle of adjuvant bleomycin, etoposide (500 mg/m²), and cisplatin (BE500P) is safe, resulting in a two-year malignant recurrence (MR) rate of 1.3 percent, similar to that reported for two cycles of BE360P, according to a study published online Jan. 1 in European Urology.

Abstract/Full Text

Routine HPV Testing May Be Warranted for Sinonasal Cancers

FRIDAY, Jan. 3, 2020 (HealthDay News) — Only one in four patients with sinonasal squamous cell carcinoma (SNSCC) is tested for human papillomavirus (HPV), according to a study published online Dec. 30 in Cancer.

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3-D Tattoo Device Aids With Nipple Reconstruction

FRIDAY, Jan. 3, 2020 (HealthDay News) — A new device allows plastic surgeons to perform three-dimensional nipple tattoos as part of breast reconstruction, according to a study published in the January issue of Plastic and Reconstructive Surgery.

Abstract/Full Text

Adverse Events Decreased With Proton Chemoradiotherapy

FRIDAY, Jan. 3, 2020 (HealthDay News) — Proton chemoradiotherapy is associated with a significantly lower risk for 90-day adverse events and a decrease in performance status during treatment compared with photon therapy, according to a study published online Dec. 26 in JAMA Oncology.

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Survivors of Childhood Cancers at Risk for Shortened Life Span

THURSDAY, Jan. 2, 2020 (HealthDay News) — Survivors of childhood cancer remain at risk for shorter life spans, especially when they receive radiotherapy, according to a study published online Jan. 2 in JAMA Oncology.

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AI System Outperforms Radiologists in Breast Cancer Prediction

THURSDAY, Jan. 2, 2020 (HealthDay News) — An artificial intelligence (AI) system can reduce false positives and false negatives in prediction of breast cancer and outperforms human readers, according to a study published online Jan. 1 in Nature.

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Leisure-Time Physical Activity Linked to Lower Cancer Risk

THURSDAY, Jan. 2, 2020 (HealthDay News) — Leisure-time physical activity at recommended levels is associated with a significantly lower risk for seven cancer types, according to a study published online Dec. 26 in the Journal of Clinical Oncology.

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Patient Experiences Modestly Worse After Hospital Acquisition

THURSDAY, Jan. 2, 2020 (HealthDay News) — Modestly worse patient experiences are seen following hospital acquisition by another hospital, according to a study published in the Jan. 2 issue of the New England Journal of Medicine.

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