Here are what the editors at HealthDay consider to be the most important developments in Pharmacy for January 2020. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Hydromorphone-CR Exposure Ups Heart Infection Risk in PWID

FRIDAY, Jan. 31, 2020 (HealthDay News) — Exposure to controlled-release hydromorphone, an opioid that can be abused through crushing and injection, is associated with an increased risk for infective endocarditis among people who inject drugs, according to a study published online Jan. 22 in The Lancet Infectious Diseases.

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Early Treatment Tied to Less Disability With Pediatric-Onset MS

FRIDAY, Jan. 31, 2020 (HealthDay News) — Timing of treatment start is an important predictor of disability accumulation in patients with pediatric-onset multiple sclerosis (MS), according to a study published online Jan. 17 in Multiple Sclerosis and Related Disorders.

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Opioid Prescribing Rates Down at State Level From 2010 to 2016

FRIDAY, Jan. 31, 2020 (HealthDay News) — Prescription drug monitoring program (PDMP) data from individual states show a decline in opioid prescribing rates in 11 participating states from 2010 to 2016, according to research published in the Jan. 31 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Electrical Cardioversion Effective for Acute A-Fib in Emergency Setting

FRIDAY, Jan. 31, 2020 (HealthDay News) — For patients in the emergency department with acute atrial fibrillation, pharmacological cardioversion followed by electrical cardioversion (drug-shock) and electrical cardioversion alone (shock-only) strategies are highly effective for restoring sinus rhythm, with similar outcomes for different pad positions, according to a study published in the Feb. 1 issue of The Lancet.

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2017 to 2018 Saw Increase in Life Expectancy in the United States

THURSDAY, Jan. 30, 2020 (HealthDay News) — From 2017 to 2018, there was an increase in life expectancy in the United States and a decrease in age-adjusted death rates, according to a January data brief published by the U.S. Centers for Disease Control and Prevention National Center for Health Statistics.

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Many Patients Receive Guideline-Nonconcordant Care for Low Back Pain

THURSDAY, Jan. 30, 2020 (HealthDay News) — Many patients who develop new low back pain (LBP) receive advanced imaging and opioids without having been prescribed nonsteroidal anti-inflammatory drugs (NSAIDs) or physical therapy (PT), according to a study published in the February issue of Medical Care.

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Just a Few Providers Account for Large Number of Opioid Scripts

THURSDAY, Jan. 30, 2020 (HealthDay News) — A small proportion of providers account for almost half of all opioid doses and about one-quarter of opioid prescriptions, according to a study published online Jan. 29 in The BMJ.

Abstract/Full Text

Promoting Mixed Chimerism Promising in Kidney Transplants

THURSDAY, Jan. 30, 2020 (HealthDay News) — For patients undergoing living kidney transplants, persistent mixed chimerism can be achieved to allow complete or partial withdrawal of immunosuppressive drugs, according to a study published in the Jan. 29 issue of Science Translational Medicine.

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FDA Tells Purell Manufacturer to Stop Making False Claims

WEDNESDAY, Jan. 29, 2020 (HealthDay News) — The maker of Purell hand sanitizers has been warned by the U.S. Food and Drug Administration to stop claiming that the products can protect people from infections and illnesses.

The New York Times Article
More Information: FDA

Benefits of Psilocybin-Assisted Psychotherapy May Be Lasting

WEDNESDAY, Jan. 29, 2020 (HealthDay News) — Psilocybin-assisted psychotherapy may promote long-term benefits in terms of reductions in anxiety, depression, and hopelessness among patients with cancer-related psychiatric distress, according to a study published online Jan. 9 in the Journal of Psychopharmacology.

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Suvorexant May Improve Insomnia With Alzheimer Disease

WEDNESDAY, Jan. 29, 2020 (HealthDay News) — Suvorexant improves total sleep time (TST) in patients with probable Alzheimer disease (AD) dementia and insomnia, according to a study published online Jan. 15 in Alzheimer’s & Dementia.

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Drug Price-Fixing Charge Laid Against ‘Pharma Bro’ Martin Shkreli

TUESDAY, Jan. 28, 2020 (HealthDay News) — So-called “Pharma Bro” Martin Shkreli faces charges of price fixing of a drug used to treat the potentially fatal condition toxoplasmosis.

CBS News Article

Racial Disparities Noted in Quality of Care for Dementia

TUESDAY, Jan. 28, 2020 (HealthDay News) — Black and Asian patients with dementia seem not to be receiving the same quality of care as white patients, according to a study published online Jan. 20 in Clinical Epidemiology.

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Naloxone Prescribing Increasing but Still Very Low

TUESDAY, Jan. 28, 2020 (HealthDay News) — Naloxone prescribing has increased but is still very low among patients at risk for opioid overdose, according to a study recently published in the Journal of General Internal Medicine.

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Wealthy Pay Most to Finance U.S. Health Care

MONDAY, Jan. 27, 2020 (HealthDay News) — Health care payments in the United States are more regressive than previously thought, according to a study published online Jan. 27 in Health Services Research.

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Prehospital Epinephrine Aids Out-of-Hospital Pediatric Cardiac Arrests

MONDAY, Jan. 27, 2020 (HealthDay News) — Prehospital administration of epinephrine may aid pediatric patients following out-of-hospital cardiac arrests (OHCAs), according to a study published in the Jan. 21 issue of the Journal of the American College of Cardiology.

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Potential Links ID’d for Marijuana Use, Cardiovascular Risks

MONDAY, Jan. 27, 2020 (HealthDay News) — In a review published in the Jan. 28 issue of the Journal of the American College of Cardiology, potential associations are presented for marijuana use and cardiovascular risks.

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Tdap or Td Vaccine May Be Used for Decennial Td Booster Doses

MONDAY, Jan. 27, 2020 (HealthDay News) — Either tetanus and diphtheria toxoids (Td) vaccine or tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine may be used for Td booster doses every 10 years or when indicated for tetanus prophylaxis in wound management, according to research published in the Jan. 24 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Many U.S. Adults Misinformed About the Flu, Vaccination

FRIDAY, Jan. 24, 2020 (HealthDay News) — Many U.S. adults are misinformed about the influenza virus and the importance of flu vaccination, according to the results of a survey released by the American Academy of Family Physicians (AAFP).

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High-Dose IV Vitamin C Does Not Speed Resolution of Septic Shock

FRIDAY, Jan. 24, 2020 (HealthDay News) — Treatment with intravenous vitamin C, hydrocortisone, and thiamine does not improve the duration of time alive and vasopressor administration-free compared with intravenous hydrocortisone alone among patients with septic shock, according to a study published online Jan. 17 in the Journal of the American Medical Association.

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Editorial

Health Care Utilization Up for Seniors With Untreated Apnea

FRIDAY, Jan. 24, 2020 (HealthDay News) — Older adult Medicare beneficiaries with untreated obstructive sleep apnea (OSA) have increased health care utilization (HCU) and costs, according to a study published online Jan. 15 in the Journal of Clinical Sleep Medicine.

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Low-Dose Aspirin Cuts Preterm Delivery in Nulliparous Women

FRIDAY, Jan. 24, 2020 (HealthDay News) — Among nulliparous women with singleton pregnancies from low-income and middle-income countries, the incidence of preterm delivery before 37 weeks is reduced for those receiving low-dose aspirin versus placebo, according to a study published in the Jan. 25 issue of The Lancet.

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Potent, Unregulated Steroid Creams Readily Available in U.S.

FRIDAY, Jan. 24, 2020 (HealthDay News) — Potent prescription-strength topical corticosteroids without a prescription (PSTCw/oP) are readily available in many U.S. cities, according to a letter to the editor published in the February issue of the Journal of the American Academy of Dermatology.

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Major Insurers Offer $55 Million to Lower Generic Drug Costs

THURSDAY, Jan. 23, 2020 (HealthDay News) — A nonprofit that develops and sells cheaper drugs will receive a $55 million investment from the Blue Cross Blue Shield Association and associated organizations to create cheaper versions of expensive generic drugs.

The New York Times Article

Fewer Than Half of Clinical Trials Comply With Reporting Laws

THURSDAY, Jan. 23, 2020 (HealthDay News) — Compliance with the U.S. Food and Drug Administration Amendments Act of 2007 is low, with only 40.9 percent of trials reporting results within one year, according to a study published online Jan. 17 in The Lancet.

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Teprotumumab Bests Placebo for Active Thyroid Eye Disease

THURSDAY, Jan. 23, 2020 (HealthDay News) — Teprotumumab is associated with better outcomes than placebo among patients with active thyroid eye disease, according to a study published in the Jan. 23 issue of the New England Journal of Medicine.

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Elagolix Cuts Heavy Menstrual Bleeding in Women With Fibroids

THURSDAY, Jan. 23, 2020 (HealthDay News) — For women with uterine fibroids, elagolix with add-back hormonal therapy is associated with a reduction in heavy menstrual bleeding compared with placebo, according to a study published in the Jan. 23 issue of the New England Journal of Medicine.

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Production of Two Excedrin Painkillers Halted

WEDNESDAY, Jan. 22, 2020 (HealthDay News) — Production and distribution of Excedrin Extra Strength and Excedrin Migraine products have been temporarily stopped, maker GlaxoSmithKline said Tuesday.

CNN Article

Fast-Track Review of ACA Lawsuit Rejected by U.S. Supreme Court

WEDNESDAY, Jan. 22, 2020 (HealthDay News) — A fast-track review of a lawsuit that threatens the Affordable Care Act was rejected Tuesday by the U.S. Supreme Court.

AP News Article

Six Active Ingredients of Sunscreen Systemically Absorbed

WEDNESDAY, Jan. 22, 2020 (HealthDay News) — Sunscreen application is associated with geometric mean maximum plasma concentrations of all six active ingredients that exceed 0.5 ng/mL, according to a study published online Jan. 21 in the Journal of the American Medical Association.

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Time of Day for Taking Warfarin Does Not Matter

WEDNESDAY, Jan. 22, 2020 (HealthDay News) — Time of day for taking warfarin makes no difference on the drug’s effectiveness, according to a study published in the January/February issue of the Annals of Family Medicine.

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Full Impact of Drug Use on U.S. Mortality Not Captured by Data

WEDNESDAY, Jan. 22, 2020 (HealthDay News) — The impact of drug use in the United States is likely to be higher than estimated, with drug-associated mortality higher than drug-coded deaths alone, according to a study published online Jan. 15 in PLOS ONE.

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ACP: Medicare for All Needed to Fix ‘Ill’ U.S. Health Care System

TUESDAY, Jan. 21, 2020 (HealthDay News) — The American College of Physicians (ACP) says the U.S. health care system “is ill and needs a bold new prescription” that includes coverage for all Americans and lower costs.

AP News Article
American College of Physicians

Medical Cannabis May Initially Aid Sleep in Chronic Pain Patients

TUESDAY, Jan. 21, 2020 (HealthDay News) — For patients with chronic pain, medical cannabis (MC) use has a positive effect on maintaining sleep; however, cannabinoids do not appear to reduce cancer pain, according to a study and review published online Jan. 20 in BMJ Supportive & Palliative Care.

Abstract/Full Text – Sznitman
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Dasatinib Tops Imatinib for Ph+ Acute Lymphoblastic Leukemia

TUESDAY, Jan. 21, 2020 (HealthDay News) — Dasatinib is associated with improved survival for pediatric patients with Philadelphia chromosome-positive acute lymphoblastic leukemia (ALL), according to a study published online Jan. 16 in JAMA Oncology.

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Fish Oil Supplement Intake Linked to Better Testicular Function

TUESDAY, Jan. 21, 2020 (HealthDay News) — For young men, fish oil supplement intake is associated with better testicular function, according to a study published online Jan. 17 in JAMA Network Open.

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Level of Antibiotic Prescribing High for Children in Tennessee

FRIDAY, Jan. 17, 2020 (HealthDay News) — The outpatient antibiotic prescribing rate for children was 1,165 per 1,000 in Tennessee in 2016, according to a study published online Jan. 15 in Infection Control & Hospital Epidemiology.

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CDC: Benzodiazepines Prescribed at 27 Office Visits Per 100 Adults

FRIDAY, Jan. 17, 2020 (HealthDay News) — Benzodiazepines were prescribed at 27 annual physician office visits per 100 adults during 2014 to 2016, according to a study published online Jan. 17 in the National Health Statistics Reports, a publication from the U.S. Centers for Disease Control and Prevention.

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Single-Payer System Would Likely Save Money

THURSDAY, Jan. 16, 2020 (HealthDay News) — There is near consensus across 30 years of economic analysis of single-payer plans that a single-payer system would reduce health expenditures in the United States, according to a review published online Jan. 15 in PLOS Medicine.

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ACA Tied to Narrowing of Disparities in Access to Care

THURSDAY, Jan. 16, 2020 (HealthDay News) — The Affordable Care Act has reduced disparities in access to health care among black, Hispanic, and white adults, according to a January data brief released by the Commonwealth Fund.

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High-Dose Erythropoietin No Benefit for Extreme Preemies

THURSDAY, Jan. 16, 2020 (HealthDay News) — For extremely preterm infants, high-dose erythropoietin treatment from 24 hours after birth does not result in a reduced risk for severe neurodevelopmental impairment or death at age 2 years, according to a study published in the Jan. 16 issue of the New England Journal of Medicine.

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Ageism Predicts Significantly Worse Health Outcomes

THURSDAY, Jan. 16, 2020 (HealthDay News) — Ageism predicts significantly worse health outcomes, according to a review published online Jan. 15 in PLOS ONE.

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Coronary Artery Disease Risk Down in Survivors of Childhood Cancer

THURSDAY, Jan. 16, 2020 (HealthDay News) — There has been a decrease in the risk for coronary artery disease among adult survivors of childhood cancer, according to a study published online Jan. 15 in The BMJ.

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2011 to 2017 Saw Increase in Spending on DMTs for MS

WEDNESDAY, Jan. 15, 2020 (HealthDay News) — From 2011 to 2017, there was an increase in gross annual expenditures on multiple sclerosis (MS) disease-modifying therapies (DMTs), with increased spending mainly driven by increases in per-prescription costs, according to a study published online Jan. 15 in Neurology.

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FDA: Weight Control Drug Lorcaserin May Raise Cancer Risk

WEDNESDAY, Jan. 15, 2020 (HealthDay News) — The prescription weight control medicine lorcaserin (Belviq, Belviq XR) may increase the risk for cancer, according to the results of a clinical trial assessing the safety of the drug, the U.S. Food and Drug Administration says.

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Evolution of Approval, Regulation Processes for Drugs Explored

WEDNESDAY, Jan. 15, 2020 (HealthDay News) — The U.S. approval and regulation processes for pharmaceutical agents have evolved during the last four decades, according to a study published in the Jan. 14 issue of the Journal of the American Medical Association.

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Vaccine Program Recovery Difficult After Public Scares

TUESDAY, Jan. 14, 2020 (HealthDay News) — Misinformation in the Danish media between 2013 and 2016 led to a 50.4 percent drop in human papillomavirus (HPV) vaccinations among girls in Denmark, according to a study published online Jan. 7 in Vaccine.

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Behavioral Therapy First Step for Overactive Bladder in Men

MONDAY, Jan. 13, 2020 (HealthDay News) — Among men with overactive bladder, combined behavioral and drug therapy is superior to drug therapy alone, but not behavioral therapy alone, for symptomatic improvement, according to a study published online Jan. 13 in JAMA Internal Medicine.

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Gout Incidence Down With SGLT2 Inhibitors in Type 2 Diabetes

MONDAY, Jan. 13, 2020 (HealthDay News) — Adults with type 2 diabetes newly prescribed a sodium-glucose cotransporter-2 (SGLT2) inhibitor have a lower incidence of gout than those prescribed a glucagon-like peptide-1 (GLP-1) receptor agonist, according to a study published online Jan. 14 in the Annals of Internal Medicine.

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Mandatory Vaccination Ups Prevalence of Vaccine Coverage

MONDAY, Jan. 13, 2020 (HealthDay News) — Mandatory vaccination is associated with increased vaccination coverage for measles and pertussis as well as reduced measles incidence in Europe, according to a study published online Jan. 13 in Pediatrics.

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Guidance Issued for Hepatic, Mesenteric Circulation Disorders

MONDAY, Jan. 13, 2020 (HealthDay News) — In a clinical guideline from the American College of Gastroenterology, published in the January issue of the American Journal of Gastroenterology, recommendations are presented for management of disorders of the hepatic and mesenteric circulation.

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Antipsychotic Use Safer Than No Use in Schizophrenia

MONDAY, Jan. 13, 2020 (HealthDay News) — Among patients with schizophrenia, long-term antipsychotic use does not appear to increase severe physical morbidity or somatic hospitalization, and mortality is lower for antipsychotic use compared with no use, according to a study published online Jan. 10 in World Psychiatry.

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Intensive Systolic BP Control May Not Benefit All Older Adults

MONDAY, Jan. 13, 2020 (HealthDay News) — Intensive systolic blood pressure (SBP) control lowers the risk for major cardiovascular events, cognitive impairment, and death in older adults; however, these benefits may not extend to older adults with lower baseline cognitive function, according to a study published online Dec. 16 in the Journal of the American Geriatrics Society.

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Total Opioid Overdose Deaths Down With Medicaid Expansion

FRIDAY, Jan. 10, 2020 (HealthDay News) — Medicaid expansion is associated with a reduction in total opioid overdose deaths and with increases in methadone-related mortality, according to a study published online Jan. 10 in JAMA Network Open.

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California May Start Producing Its Own Medicines

FRIDAY, Jan. 10, 2020 (HealthDay News) — A proposal for California to contract generic drug companies to make medications would make the state the first in the country to produce its own medications.

AP News Article

Two More Heartburn Meds Recalled Due to Possible Carcinogen

FRIDAY, Jan. 10, 2020 (HealthDay News) — The U.S. Food and Drug Administration is adding to a list of recalled lots of popular heartburn medications — including generic forms of Zantac — because the pills might contain small amounts of the suspected carcinogen N-nitrosodimethylamine (NDMA).

CBS News Article
FDA: Appco Announcement
FDA: Northwind Announcement

Treatment Guidelines Updated for Hand, Hip, Knee Osteoarthritis

FRIDAY, Jan. 10, 2020 (HealthDay News) — In the 2019 American College of Rheumatology/Arthritis Foundation Guideline, published online Jan. 6 in Arthritis Care & Research, updated recommendations are presented for the management of hand, hip, and knee osteoarthritis (OA).

Abstract/Full Text

Neighborhood Disadvantage Impacts Hospital Quality Ratings

FRIDAY, Jan. 10, 2020 (HealthDay News) — Hospitals caring for neighborhoods with high levels of disadvantage may have lower hospital ratings due to social risk factors (SRFs) in the community, according to a study published online Dec. 30 in Medical Care.

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CDC Warns of Tough Flu Season Ahead

THURSDAY, Jan. 9, 2019 (HealthDay News) — Flu cases and flu-related hospitalizations have risen sharply since October, with at least 6.4 million reported cases and 55,000 hospitalizations, according to the U.S. Centers for Disease Control and Prevention. At least 2,900 Americans have died from the flu, the CDC reported late last week.

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Four Weeks of Active TENS Beneficial for Fibromyalgia

THURSDAY, Jan. 9, 2020 (HealthDay News) — Four weeks of active transcutaneous electrical nerve stimulation (TENS) results in significant improvement in movement-evoked pain and other clinical outcomes compared with placebo-TENS or no TENS, according to a study recently published in Arthritis & Rheumatology.

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Clinical Guidelines Developed for Managing Nosebleeds

THURSDAY, Jan. 9, 2020 (HealthDay News) — In a clinical practice guideline from the American Academy of Otolaryngology-Head and Neck Surgery Foundation, published online Jan. 7 in Otolaryngology-Head and Neck Surgery, recommendations are presented for the management of nosebleeds.

Clinical Practice Guideline
Executive Summary

Antipsychotic Initiation Ups Risk for Head Injury, TBI in Alzheimer Disease

WEDNESDAY, Jan. 8, 2020 (HealthDay News) — Individuals with Alzheimer disease (AD) initiating antipsychotics have an increased risk for head injuries and traumatic brain injury (TBI), according to a study published online Jan. 7 in the Journal of the American Geriatrics Society.

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Large Gap Found in Health Administrative Spending for U.S., Canada

WEDNESDAY, Jan. 8, 2020 (HealthDay News) — There is a large and widening gap in health administrative spending between the United States and Canada, according to a study published online Jan. 7 in the Annals of Internal Medicine.

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Luspatercept Mitigates Anemia in Lower-Risk Myelodysplastic Syndromes

WEDNESDAY, Jan. 8, 2020 (HealthDay News) — For patients with lower-risk myelodysplastic syndromes with ring sideroblasts who have been receiving regular red-cell transfusions, luspatercept reduces the severity of anemia compared with placebo, according to a study published in the Jan. 9 issue of the New England Journal of Medicine.

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Recent Years Saw Drop in Opioid Prescribing at ED Discharge

WEDNESDAY, Jan. 8, 2020 (HealthDay News) — The percentage of emergency department visits with an opioid prescribed increased from 2006-2007 to 2010-2011 then decreased to 2016-2017, according to a study published online Jan. 8 in the National Health Statistics Reports, a publication from the U.S. Centers for Disease Control and Prevention.

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CDC: Young Adults Who Ever Received HPV Vaccine on the Rise

TUESDAY, Jan. 7, 2020 (HealthDay News) — From 2013 to 2018, there was an increase in the percentage of adults aged 18 to 26 years who received one or more doses or the recommended number of doses of human papillomavirus (HPV) vaccine, according to a January data brief published by the U.S. Centers for Disease Control and Prevention National Center for Health Statistics.

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CDC Data May Be Underreporting Scope of Overdose Deaths

TUESDAY, Jan. 7, 2020 (HealthDay News) — Data from the U.S. Centers for Disease Control and Prevention may be underreporting overdose deaths caused by opioids and other drugs, according to a report published online Jan. 7 in Drug and Alcohol Dependence.

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Folic Acid, Zinc Supplements in Men No Benefit in Infertility

TUESDAY, Jan. 7, 2020 (HealthDay News) — For couples seeking infertility treatment, folic acid and zinc supplementation compared with placebo for male partners does not significantly improve semen quality or live birth rates, according to a study published in the Jan. 7 issue of the Journal of the American Medical Association.

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Use of Powder in Genital Area Not Linked to Ovarian Cancer

TUESDAY, Jan. 7, 2020 (HealthDay News) — Use of powder in the genital area does not appear to be significantly associated with incident ovarian cancer, according to a study published in the Jan. 7 issue of the Journal of the American Medical Association.

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Prevalence of Buprenorphine-Waivered Prescribers Increasing

TUESDAY, Jan. 7, 2020 (HealthDay News) — From 2007 to 2017, there was an increase in the prevalence of buprenorphine-waivered prescribers in the United States, according to a research letter published online Jan. 7 in the Annals of Internal Medicine.

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Few Youths Receive Addiction Treatment After Opioid Overdose

TUESDAY, Jan. 7, 2020 (HealthDay News) — Less than one-third of youths surviving an opioid overdose receive timely addiction treatment, according to a study published online Jan. 6 in JAMA Pediatrics.

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Guideline Issued for Testosterone Therapy in Adult Men

MONDAY, Jan. 6, 2020 (HealthDay News) — In a new evidence-based clinical practice guideline, published online Jan. 7 in the Annals of Internal Medicine, recommendations are presented for testosterone treatment in men with age-related low testosterone.

Evidence Review (subscription or payment may be required)
Clinical Guideline
Editorial (subscription or payment may be required)

2014 to 2016 Saw Decline in U.S. Adults Prescribed Opioids

MONDAY, Jan. 6, 2020 (HealthDay News) — From 2014 to 2016, there was a decrease in the proportion of U.S. adults who were prescribed opioids, with a larger decrease seen for those who reported moderate or more severe pain versus less-than-moderate pain, according to a report published in the January issue of Health Affairs.

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Price Hikes for Hundreds of Medications

MONDAY, Jan. 6, 2020 (HealthDay News) — U.S. drug companies have started the new year by raising the prices of hundreds of medications.

CBS News Article

Teens Who Misuse Opioids Likely to Engage in Other Risky Behaviors

MONDAY, Jan. 6, 2020 (HealthDay News) — Adolescents who report misusing prescription opioids are more likely to have engaged in a range of other risky behaviors, according to a study published online Jan. 6 in Pediatrics.

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One-Cycle BE500P Seems Safe for High-Risk Early Testicular Cancer

MONDAY, Jan. 6, 2020 (HealthDay News) — For high-risk stage 1 nonseminoma germ cell tumors of the testis (NSGCTT), one cycle of adjuvant bleomycin, etoposide (500 mg/m²), and cisplatin (BE500P) is safe, resulting in a two-year malignant recurrence (MR) rate of 1.3 percent, similar to that reported for two cycles of BE360P, according to a study published online Jan. 1 in European Urology.

Abstract/Full Text

Public Policy Recs Updated for Familial Hypercholesterolemia

FRIDAY, Jan. 3, 2020 (HealthDay News) — In a special communication article, published online Jan. 2 in JAMA Cardiology, updated recommendations are presented for reducing the clinical and public health burden of familial hypercholesterolemia (FH).

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New Continuous Glucose Monitor May Cut Hypoglycemia in T1DM

FRIDAY, Jan. 3, 2020 (HealthDay News) — Intermittently scanned continuous glucose monitoring (isCGM) results in higher treatment satisfaction among adults with type 1 diabetes, according to a study published online Dec. 24 in Diabetes Care.

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APO(a)-LRX Found to Reduce Lipoprotein(a) Levels

THURSDAY, Jan. 2, 2020 (HealthDay News) — For patients with elevated lipoprotein(a) levels and established cardiovascular disease, hepatocyte-directed antisense oligonucleotide AKCEA-APO(a)-LRX (APO(a)-LRX) reduces lipoprotein(a) levels, according to a study published online Jan. 1 in the New England Journal of Medicine.

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Guidance Developed for Providing Quality STD Care

THURSDAY, Jan. 2, 2020 (HealthDay News) — In a report published in the Jan. 3 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report, recommendations are presented for providing quality sexually transmitted disease (STD) clinical services.

Abstract/Full Text

Patient Experiences Modestly Worse After Hospital Acquisition

THURSDAY, Jan. 2, 2020 (HealthDay News) — Modestly worse patient experiences are seen following hospital acquisition by another hospital, according to a study published in the Jan. 2 issue of the New England Journal of Medicine.

Abstract/Full Text (subscription or payment may be required)

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