The following is a summary of “Psoriasis and hidradenitis suppurativa: A large-scale population-based study,” published in the MAY 2023 issue of Dermatology by Kridin, et al.
The presence of both psoriasis and hidradenitis suppurativa (HS) has been reported, but the exact relationship between these conditions has not been definitively established. For a study, researchers sought to investigate the association between psoriasis and HS using a large-scale real-life computerized database.
A cross-sectional study was conducted to compare the prevalence of HS among patients with psoriasis to age-, sex-, and ethnicity-matched control subjects.
A total of 68,836 patients with psoriasis and 68,836 controls were included in the study. The prevalence of HS was higher in patients with psoriasis compared to the control group (0.3% vs. 0.2%, respectively; odds ratio, 1.8; 95% confidence interval, 1.5-2.3; P < .001). After adjusting for smoking, obesity, and other comorbidities in a multivariate analysis, psoriasis remained significantly associated with HS (odds ratio, 1.8; 95% CI, 1.4-2.2; P < .001). Patients with both psoriasis and HS were found to be significantly younger (mean age 39.0 ± 15.7 years vs. 42.6 ± 21.2 years, P = .015) and had a higher prevalence of obesity (35.1% vs. 25.3%, P = .001) and smoking (58.5% vs. 37.3%, P < .001) compared to patients with psoriasis alone.
The study revealed a positive association between HS and psoriasis. Further longitudinal observational studies were required to confirm the findings in different study populations.