The aim is to understand Neuromodulation is used in patients with drug‐resistant epilepsy (DRE), particularly when resective medical procedure is absurd or seizures are multifocal.1 The RNS System (NeuroPace, Mountain View, CA, USA) can convey responsive electrical incitement once epileptiform action is distinguished, consequently hindering seizure spread. Long‐term information have demonstrated that RNS gives supported seizure decrease proceeded with progress with every time of treatment including positive wellbeing and adequacy results. The RNS System isn’t affirmed in patients under 18, albeit a basic requirement for novel treatment modalities in this weak populace continue. We present two pediatric patients with drug‐resistant epilepsy auxiliary to Lennox‐Gastaut Syndrome (LGS) and autism spectrum disorder (ASD) treated with the RNS System. The two patients have encountered 75–99% clinical seizure decreases in >1 year of follow‐up. RNS as a closed‐loop framework requires less electrical incitement contrasted with the open‐loop DBS framework, subsequently giving higher adequacy, lower power utilization, longer battery life expectancy and eventually less medical procedures being acted in this weak populace. We delineate that kids with diffuse beginning, multifocal epilepsy, including frontal and thalamic circuits thought to exist in the age of LGS seizures, can be treated with responsive neurostimulation securely and adequately, focusing on thalamic networks, and dodging palliative separations and resections.

Reference link- https://onlinelibrary.wiley.com/doi/10.1002/acn3.51173

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