There has been no research comparing the course of lichen sclerosus in boys and girls, and there have been few investigations on pediatric lichen sclerosus. For a study, researchers sought to review and compare epidemiology, symptoms and signs, genetic background, risk factors, treatment, and prognosis across all publications on boys and girls with lichen sclerosis. The databases Embase, Medline, Cochrane, and Web of Science were used to conduct a systematic search. Information on children aged 0 to 18 years old was required, and a clinical or histologic diagnosis of lichen sclerosus. The literature was examined from 1985 to 2021. A total of 1,780 items were found in the search, with 90 appropriate for inclusion. Although boys and girls were identical in many ways, therapy and follow-up were handled differently. The clinical approach to lichen sclerosus in boys and girls was generally different, but there were many commonalities. More study was needed, particularly on follow-up, to understand the course of lichen sclerosus better and build an advanced management strategy for children.
Source:onlinelibrary.wiley.com/doi/10.1111/pde.14967
