Advertisement

 

 

Lipodystrophy Syndromes.

Lipodystrophy Syndromes.
Author Information (click to view)

Hussain I, Garg A,


Hussain I, Garg A, (click to view)

Hussain I, Garg A,

Advertisement
Share on FacebookTweet about this on TwitterShare on LinkedIn

Endocrinology and metabolism clinics of North America 2016 10 0645(4) 783-797 pii 10.1016/j.ecl.2016.06.012

Abstract

Lipodystrophies are heterogeneous disorders characterized by varying degrees of body fat loss and predisposition to insulin resistance and its metabolic complications. They are subclassified depending on degree of fat loss and whether the disorder is genetic or acquired. The two most common genetic varieties include congenital generalized lipodystrophy and familial partial lipodystrophy; the two most common acquired varieties include acquired generalized lipodystrophy and acquired partial lipodystrophy. Highly active antiretroviral therapy-induced lipodystrophy in patients infected with human immunodeficiency virus and drug-induced localized lipodystrophy are common subtypes. The metabolic abnormalities associated with lipodystrophy include insulin resistance, hypertriglyceridemia, and hepatic steatosis. Management focuses on preventing and treating metabolic complications.

Submit a Comment

Your email address will not be published. Required fields are marked *

five + 19 =

[ HIDE/SHOW ]