Offspring of mothers with T1D have lower school test scores than the general population but similar test scores to offspring of fathers with T1D, according to a study published in PLOS Medicine. Anne Lærke Spangmose, MD, and colleagues compared school test scores for public school grades 2, 3, 4, 6, and 8 between offspring of mothers with T1D (2,144 children), offspring of fathers with T1D (3,474 children), and the general population (616,455 children). Mean test scores were 54.2 (out of 100) in offspring of mothers with T1D, 54.4 in offspring of fathers with T1D, and 56.4 in the general population. The mean differences in test scores were −1.59 between offspring of mothers with T1D and the general population and −0.78 between offspring of fathers with T1D and the general population in an adjusted analysis. There was no significant difference in the adjusted mean test scores between offspring of mothers and fathers with T1D.

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