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Magnetic Lenz lenses improve the limit-of-detection in nuclear magnetic resonance.

Magnetic Lenz lenses improve the limit-of-detection in nuclear magnetic resonance.
Author Information (click to view)

Spengler N, While PT, Meissner MV, Wallrabe U, Korvink JG,


Spengler N, While PT, Meissner MV, Wallrabe U, Korvink JG, (click to view)

Spengler N, While PT, Meissner MV, Wallrabe U, Korvink JG,

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PloS one 2017 08 1512(8) e0182779 doi 10.1371/journal.pone.0182779
Abstract

A high NMR detection sensitivity is indispensable when dealing with mass and volume-limited samples, or whenever a high spatial resolution is required. The use of miniaturised RF coils is a proven way to increase sensitivity, but situations may arise where space restrictions could prevent the use of a small resonant coil, e.g., in the interior of the smallest practicable micro-coils. We present the use of magnetic lenses, denoted as Lenz lenses due to their working principle, to focus the magnetic flux of an RF coil into a smaller volume and thereby locally enhance the sensitivity of the NMR experiment-at the expense of the total sensitive volume. Besides focusing, such lenses facilitate re-guiding or re-shaping of magnetic fields much like optical lenses do with light beams. For the first time we experimentally demonstrate the use of Lenz lenses in magnetic resonance and provide a compact mathematical description of the working principle. Through simulations we show that optimal arrangements can be found.

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