An international randomized control trial has found that kyphoplasty appears to be an effective and safe treatment that rapidly reduces pain and improves function for patients with cancer who have painful vertebral compression fractures (VCFs). The average scores on a disability scale for patients receiving kyphoplasty for VCFs changed from 17.6 at baseline to 9.1 at 1 month. Conversely, the average scores on the scale for the control group changed from 18.2 to 18.0.