Here are what the editors at HealthDay consider to be the most important developments in Gastroenterology for March 2019. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Starting Colorectal Cancer Screening at Age 45 Years Is Cost-Effective

FRIDAY, March 29, 2019 (HealthDay News) — Starting colorectal cancer (CRC) screening at age 45 instead of 50 years seems cost-effective, but greater benefits could be achieved by increasing participation rates for unscreened older individuals, according to a study published online March 28 in Gastroenterology.

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Use of Biologics to Treat IBD in U.S. Adults May Be Suboptimal

FRIDAY, March 29, 2019 (HealthDay News) — Varied study design and methodology make it difficult to assess real-world trends in adherence and persistence in use of biologics among U.S. adults with inflammatory bowel disease (IBD), according to a review published online March 14 in the Journal of Clinical Pharmacy and Therapeutics.

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Long-Term Phentermine Use Safe, Effective for Weight Loss

FRIDAY, March 29, 2019 (HealthDay News) — Patients taking phentermine for weight loss for more than three months experience greater weight loss without an increased risk for incident cardiovascular disease or death, according to a study published online March 21 in Obesity.

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Tooth Loss May Up Pancreatic Cancer Risk in Black Women

THURSDAY, March 28, 2019 (HealthDay News) — Tooth loss is associated with an increased risk for incident pancreatic cancer in African-American women, according to a study published online March 28 in Cancer Epidemiology, Biomarkers & Prevention.

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Doctors With Malpractice Claims More Likely to Leave Medicine

THURSDAY, March 28, 2019 (HealthDay News) — Physicians with one or more paid malpractice claims are more likely to leave practice or shift into smaller practice settings, according to a study published in the March 28 issue of the New England Journal of Medicine.

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Tx Adherence for Inflammatory Bowel Dz Lower in the Educated

WEDNESDAY, March 27, 2019 (HealthDay News) — Nonadherence to inflammatory bowel disease (IBD) treatment is more common among wealthier, more educated patients, according to a study published online March 18 in JGH Open.

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Douglas County, Colorado, Ranked as Healthiest Community

TUESDAY, March 26, 2019 (HealthDay News) — The 2019 healthiest community in America is Douglas County, Colorado, according to a report published online March 26 by U.S. News & World Report, in conjunction with the Aetna Foundation.

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Avocados Recalled by California Company

MONDAY, March 25, 2019 (HealthDay News) — Possible listeria contamination has led to a recall of avocados by Henry Avocado, a grower and distributor based near San Diego.

AP News Article
More Information: FDA

2019 Residency Match Day Was Largest in History

MONDAY, March 25, 2019 (HealthDay News) — The 2019 Main Residency Match was the largest in history, with a record high of 38,376 applicants for 35,185 positions, according to 2019 Match Day results released by the National Resident Matching Program.

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HBV, HCV Control Aids Kidney Transplant Outcomes

MONDAY, March 25, 2019 (HealthDay News) — The outcomes of kidney transplants in patients with viral suppression are as good as those for kidney transplants in patients not infected with hepatitis B virus (HBV) or hepatitis C virus (HCV), according to a study published online March 14 in the Journal of Hepatology.

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Many Patients Still Employ Strategies to Reduce Prescription Drug Costs

FRIDAY, March 22, 2019 (HealthDay News) — The number of adults reporting the use of strategies, such as requesting a lower-cost medication or not using medication as prescribed, to reduce prescription drug costs remained stable in 2015 to 2017, according to a March data brief published by the U.S. Centers for Disease Control and Prevention National Center for Health Statistics.

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Antibiotics, PPIs Tied to Higher C. Diff Risk in Hospitalized Children

THURSDAY, March 21, 2019 (HealthDay News) — Previous antibiotic exposure and use of proton pump inhibitors (PPIs) may be risk factors for Clostridioides (formerly Clostridium) difficile infection (CDI) in hospitalized pediatric patients, according to a review published online March 7 in Infection Control & Hospital Epidemiology.

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Overall, Physicians Are Happy and Enjoy Their Lives

WEDNESDAY, March 20, 2019 (HealthDay News) — Overall, physicians are happy and enjoy their lives, according to the 2019 American Academy of Family Physicians (AAFP)/CompHealth Physician Happiness Survey published online March 19.

2019 AAFP/CompHealth Physician Happiness Survey

Novel Checklist Can Distinguish Anthrax Exposure From Other Illnesses

TUESDAY, March 19, 2019 (HealthDay News) — A newly developed checklist can rapidly identify anthrax cases after a suspected mass exposure, according to a study published online March 19 in the Annals of Internal Medicine.

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Average of 8.8 Inactive Ingredients Found in Oral Medications

MONDAY, March 18, 2019 (HealthDay News) — Oral forms of medications contain an average of 8.8 inactive ingredients, many of which could cause adverse reactions, according to a perspective piece published in the March 13 issue of Science Translational Medicine.

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Adenocarcinoma, High-Grade Dysplasia Up With Barrett Esophagus

MONDAY, March 18, 2019 (HealthDay News) — The prevalence of high-grade dysplasia (HGD) and esophageal adenocarcinoma (EAC) has significantly increased since 1995 in patients with Barrett esophagus (BE), according to a study published in the February issue of Gastrointestinal Endoscopy.

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Physician Burnout Rate Increased From 2014 to 2017

FRIDAY, March 15, 2019 (HealthDay News) — From 2014 to 2017, there was an increase in physician burnout, with early-career physicians being the most susceptible, according to a study published online March 15 in JAMA Network Open.

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ASCO: Guidelines Released for Early Detection, Treatment of CRC

FRIDAY, March 15, 2019 (HealthDay News) — Expert guidance has been provided on the early detection of colorectal cancer and on treatment and posttreatment follow-up; the two guidelines were recently published online in the Journal of Global Oncology.

Abstract/Full Text – Lopes
Abstract/Full Text – Costas-Chavarri

Head of National Cancer Institute Named Acting FDA Commissioner

WEDNESDAY, March 13, 2019 (HealthDay News) — The U.S. Food and Drug Administration will temporarily be overseen by the head of the National Cancer Institute when FDA Commissioner Scott Gottlieb, M.D., leaves the post next month.

AP News Article

CDC: Most Americans Report Excellent, Good Health

WEDNESDAY, March 13, 2019 (HealthDay News) — Most Americans report having excellent or good health and have a usual place to go for medical care, according to a report published March 13 for the National Health Interview Survey Early Release Program.

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Stillbirth Risk Up With High Serum Bile Acids in Pregnancy

TUESDAY, March 12, 2019 (HealthDay News) — The risk of stillbirth is increased in women with intrahepatic cholestasis of pregnancy when serum bile acids concentrations are ≥100 µmol/L or more, according to a review published in the March 2 issue of The Lancet.

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Editorial

Distinct Etiology Found for Colorectal Cancer With Early Onset

MONDAY, March 11, 2019 (HealthDay News) — Onset of colorectal cancer (CRC) in adults younger than 50 years is distinct from onset in patients aged 50 years or older, according to a study published online March 11 in Cancer.

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Surgery for Uncomplicated Appendicitis Typically Yields Satisfactory Outcomes

FRIDAY, March 8, 2019 (HealthDay News) — Preoperative imaging, a laparoscopic approach, and excellent clinical outcomes are the norm for the surgical management of uncomplicated appendicitis in U.S. adults, according to research published in the March issue of Surgery.

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Complication Rate After Bariatric Surgery Higher for Black Patients

THURSDAY, March 7, 2019 (HealthDay News) — Black patients have higher rates of 30-day complications and resource use than white patients after bariatric surgery, according to a study published online March 6 in JAMA Surgery.

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Preoperative Frailty Linked to Surgical Outcomes, Costs

WEDNESDAY, March 6, 2019 (HealthDay News) — Preoperative frailty is associated with surgical outcomes and costs in patients undergoing elective surgery, according to a study published online March 1 in the Journal of the American College of Surgeons.

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FDA Commissioner Dr. Scott Gottlieb Resigns

TUESDAY, March 5, 2019 (HealthDay News) — In what probably came as a surprise to many, U.S. Food and Drug Administration Commissioner Scott Gottlieb, M.D., announced his resignation on Tuesday. Gottlieb is leaving the FDA because he wants to spend more time with his wife and three young daughters — twins aged 9 and a 5-year-old — one official said. He currently commutes each week from the family home in Connecticut to his Washington, D.C., office.

The Washington Post Article

Recommendations Developed for Ulcerative Colitis Management

TUESDAY, March 5, 2019 (HealthDay News) — Recommendations have been developed for management of adults with ulcerative colitis (UC); the American College of Gastroenterology clinical guideline was published online Feb. 21 in the American Journal of Gastroenterology.

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Readmission for Patients With Sepsis Common and Costly

MONDAY, March 4, 2019 (HealthDay News) — Readmission after sepsis hospitalization is common and is associated with considerable costs, according to a study published in the March issue of CHEST.

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Higher Intake of Whole Grains May Lower Risk for Liver Cancer

MONDAY, March 4, 2019 (HealthDay News) — Higher intake of whole grains may be associated with a lower risk for hepatocellular carcinoma (HCC) among U.S. adults, according to a study published online Feb. 21 in JAMA Oncology.

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FDA Warns Americans Not to Buy Drugs From Canadian Company

FRIDAY, March 1, 2019 (HealthDay News) — A large Canadian drug distributor sells unapproved and mislabeled medicines to Americans, the U.S. Food and Drug Administration warned Thursday. The distributor disputes the claim, however.

The New York Times Article
More Information: FDA

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