Here are what the editors at HealthDay consider to be the most important developments in Pediatrics for March 2019. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Therapeutic Ball Pits Found to Harbor Pathogenic Germs

FRIDAY, March 29, 2019 (HealthDay News) — Therapeutic ball pits in physical therapy clinics may pose an infection hazard, according to a study published in the April issue of the American Journal of Infection Control.

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High Prenatal Omega-6:Omega-3 Ratio Linked to ADHD at Age 7

FRIDAY, March 29, 2019 (HealthDay News) — A higher prenatal omega-6:omega-3 long chain polyunsaturated fatty acid ratio in cord plasma is associated with a higher attention-deficit/hyperactivity disorder (ADHD) index score for the child at age 7 years, according to a study published online March 28 in The Journal of Pediatrics.

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CDC: 2017 to 2018 Saw Increase in Enterovirus D68 Detection

FRIDAY, March 29, 2019 (HealthDay News) — Based on active surveillance data of acute respiratory illness (ARI), enterovirus D68 (EV-D68) was detected in 0.8 percent of patients in 2017 and in 13.9 percent in 2018, according to research published in the March 29 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Dietary Fatty Acid Intake Linked to Pediatric Asthma Morbidity

FRIDAY, March 29, 2019 (HealthDay News) — Intake of omega-3 and omega-6 is associated with pediatric asthma morbidity and may modify the response to indoor particulate matter (PM), according to a study published online March 29 in the American Journal of Respiratory and Critical Care Medicine.

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Drug Survival Rates Highest for Ustekinumab for Pediatric Psoriasis

THURSDAY, March 28, 2019 (HealthDay News) — In real-life conditions, drug survival rates are higher for ustekinumab than for adalimumab and etanercept for all treatments and types of psoriasis in children, according to a study published online March 18 in the Journal of the European Academy of Dermatology and Venereology.

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Doctors With Malpractice Claims More Likely to Leave Medicine

THURSDAY, March 28, 2019 (HealthDay News) — Physicians with one or more paid malpractice claims are more likely to leave practice or shift into smaller practice settings, according to a study published in the March 28 issue of the New England Journal of Medicine.

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Electronic Books Tied to Less Verbalization Among Parents, Toddlers

WEDNESDAY, March 27, 2019 (HealthDay News) — Parents and toddlers verbalize less with electronic books than with print books, and collaboration scores are higher with print books, according to a study published online March 25 in Pediatrics.

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Infants Born Weighing <400 g Who Survive at Risk for Severe Morbidity

WEDNESDAY, March 27, 2019 (HealthDay News) — One-fifth of infants born with a birth weight (BW) less than 400 g survive to 18 to 26 months’ corrected age, but they are at high risk for neurodevelopmental impairment, according to a study published online March 25 in JAMA Pediatrics.

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Maltreatment in Childhood May Affect Course of Adult Depression

WEDNESDAY, March 27, 2019 (HealthDay News) — Early life stress caused by childhood maltreatment can alter brain structure, which may increase the risk for adverse disease courses in patients with major depression, according to a study published in the April issue of The Lancet Psychiatry.

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U.S. Measles Cases Hit 314 This Year

TUESDAY, March 26, 2019 (HealthDay News) — There have been at least 314 reported cases of measles in the United States so far this year, according to new government data.

CNN Article
The New York Times Article
More Information: CDC

Douglas County, Colorado, Ranked as Healthiest Community

TUESDAY, March 26, 2019 (HealthDay News) — The 2019 healthiest community in America is Douglas County, Colorado, according to a report published online March 26 by U.S. News & World Report, in conjunction with the Aetna Foundation.

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Blindfolding Leader Improves Pediatric Resuscitation Training

TUESDAY, March 26, 2019 (HealthDay News) — Team leaders who wear a blindfold during pediatric resuscitation simulation-based training show improved leadership skills compared with standard training teams, according to a study recently published in Frontiers in Pediatrics.

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Mumps Outbreak at Temple University Reaches 74 Cases

MONDAY, March 25, 2019 (HealthDay News) — A mumps outbreak that began last month at Temple University in Philadelphia has reached 15 confirmed and 59 probable cases.

CNN Article
More Information: CDC

Digital Intervention Ups Socialization in Children With Autism

MONDAY, March 25, 2019 (HealthDay News) — An artificial intelligence-driven wearable behavioral intervention, Superpower Glass, can improve social outcomes for children with autism spectrum disorder (ASD), according to a study published online March 25 in JAMA Pediatrics.

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Avocados Recalled by California Company

MONDAY, March 25, 2019 (HealthDay News) — Possible listeria contamination has led to a recall of avocados by Henry Avocado, a grower and distributor based near San Diego.

AP News Article
More Information: FDA

Policies Recommended to Reduce Sugary Drink Intake in Youth

MONDAY, March 25, 2019 (HealthDay News) — In a joint policy statement published online March 25 in Pediatrics, the American Academy of Pediatrics and the American Heart Association have endorsed a number of public health measures designed to reduce sugary drink consumption among children and adolescents.

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2019 Residency Match Day Was Largest in History

MONDAY, March 25, 2019 (HealthDay News) — The 2019 Main Residency Match was the largest in history, with a record high of 38,376 applicants for 35,185 positions, according to 2019 Match Day results released by the National Resident Matching Program.

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Guidance Offered for Managing Therapies in Children With Disability

MONDAY, March 25, 2019 (HealthDay News) — In a clinical report published online March 25 in Pediatrics, guidance is provided for managing therapy services for children with disabilities.

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Analysis IDs Messages Behind Antivaccination Comments

FRIDAY, March 22, 2019 (HealthDay News) — Arguments against vaccination remain consistent within subgroups of individuals, according to a study published online March 18 in Vaccine.

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Tyson Recalls 69,000 Pounds of Chicken Strip Products

FRIDAY, March 22, 2019 (HealthDay News) — More than 69,000 pounds of frozen, ready-to-eat chicken strip products have been recalled by Tyson Foods because they may contain pieces of metal.

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Stricter Gun Laws Tied to Safer High Schools

FRIDAY, March 22, 2019 (HealthDay News) — The adoption of stricter state gun laws is associated with improvements in school climate, including fewer students carrying weapons, according to a study published online March 21 in the Journal of Epidemiology & Community Health.

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Prenatal Pesticide Exposure Linked to Increased Risk for Autism

FRIDAY, March 22, 2019 (HealthDay News) — Prenatal exposure to ambient pesticides within 2,000 m of maternal residence during pregnancy is associated with an increased risk for autism spectrum disorder, according to a study published online March 20 in The BMJ.

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DG/health NATURALS Cough Syrup + Mucus for Infants Recalled

THURSDAY, March 21, 2019 (HealthDay News) — One lot of DG/health NATURALS baby Cough Syrup + Mucus is being recalled due to possible contamination with potentially harmful bacteria, says maker Kingston Pharma, LLC.

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In Youth With ADHD, New-Onset Psychosis Up With Amphetamines

THURSDAY, March 21, 2019 (HealthDay News) — For adolescents and young adults with attention-deficit/hyperactivity disorder (ADHD), new-onset psychosis occurs more often with amphetamine use versus methylphenidate use, according to a study published in the March 21 issue of the New England Journal of Medicine.

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Mothers of Children With Eczema More Likely to Have Exhaustion

THURSDAY, March 21, 2019 (HealthDay News) — Mothers of children with atopic dermatitis (AD) are more likely to report difficulty falling asleep and daytime exhaustion, according to a study published online March 20 in JAMA Dermatology.

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Antibiotics, PPIs Tied to Higher C. Diff Risk in Hospitalized Children

THURSDAY, March 21, 2019 (HealthDay News) — Previous antibiotic exposure and use of proton pump inhibitors (PPIs) may be risk factors for Clostridioides (formerly Clostridium) difficile infection (CDI) in hospitalized pediatric patients, according to a review published online March 7 in Infection Control & Hospital Epidemiology.

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Younger Female Blood Donors Vulnerable to Iron Deficiency

THURSDAY, March 21, 2019 (HealthDay News) — Blood donation is associated with iron deficiency among both adolescent girls and younger adult women in the United States, according to a study recently published in Transfusion.

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Overall, Physicians Are Happy and Enjoy Their Lives

WEDNESDAY, March 20, 2019 (HealthDay News) — Overall, physicians are happy and enjoy their lives, according to the 2019 American Academy of Family Physicians (AAFP)/CompHealth Physician Happiness Survey published online March 19.

2019 AAFP/CompHealth Physician Happiness Survey

Sugary Drinks Tied to Cardiovascular Disease Mortality

WEDNESDAY, March 20, 2019 (HealthDay News) — Consumption of sugar-sweetened beverages (SSBs) is associated with increased mortality, mainly cardiovascular disease (CVD) mortality, according to a study published online March 18 in Circulation.

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Favorable Outcomes Seen in Long Term for ALLR3 Trial

TUESDAY, March 19, 2019 (HealthDay News) — For children with B-cell precursor acute lymphoblastic leukemia with late bone marrow relapse, risk stratification by minimal residual disease seems to be an effective strategy for treatment, according to a study recently published in The Lancet Haematology.

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Analgesics in Pregnancy Do Not Seem to Cause Offspring Asthma

TUESDAY, March 19, 2019 (HealthDay News) — Analgesics taken during pregnancy, including opioids, antimigraine drugs, and paracetamol, do not appear to cause asthma, according to a study published online March 17 in the European Respiratory Journal.

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Novel Checklist Can Distinguish Anthrax Exposure From Other Illnesses

TUESDAY, March 19, 2019 (HealthDay News) — A newly developed checklist can rapidly identify anthrax cases after a suspected mass exposure, according to a study published online March 19 in the Annals of Internal Medicine.

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Multiple Layers of Protection Recommended to Prevent Drowning

MONDAY, March 18, 2019 (HealthDay News) — Multiple layers of protection are recommended to prevent drowning, according to a policy statement published online March 15 in Pediatrics.

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In Utero Ultrafine Particle Exposure Tied to Asthma in Offspring

MONDAY, March 18, 2019 (HealthDay News) — Exposure to ultrafine particles (UFPs; <0.1 μm) during the second trimester in utero is linked to the subsequent onset of asthma in children, according to a study published online Feb. 20 in the American Journal of Respiratory and Critical Care Medicine.

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Machine-Learning Models Allow Early Detection of Sepsis in NICU

MONDAY, March 18, 2019 (HealthDay News) — Machine-learning models that use electronic health record (EHR) data can identify infants with sepsis in the neonatal intensive care unit hours before clinical recognition, according to a study published online Feb. 22 in PLOS ONE.

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2011 to 2015 Saw Increase in Psychiatric ED Visits for Youth

MONDAY, March 18, 2019 (HealthDay News) — From 2011 to 2015, there was an increase in visits to the emergency department for psychiatric purposes among youth across the United States, according to a study published online March 18 in Pediatrics.

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Average of 8.8 Inactive Ingredients Found in Oral Medications

MONDAY, March 18, 2019 (HealthDay News) — Oral forms of medications contain an average of 8.8 inactive ingredients, many of which could cause adverse reactions, according to a perspective piece published in the March 13 issue of Science Translational Medicine.

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Young Child Goes to ED for Medicine Poisoning Every 10 Minutes

FRIDAY, March 15, 2019 (HealthDay News) — The number of children younger than age 6 years treated at U.S. emergency departments for medicine poisonings has declined in recent years, but there were still nearly 52,000 cases in 2017, a new report says.

CNN Article
Safe Kids Worldwide Report

Physician Burnout Rate Increased From 2014 to 2017

FRIDAY, March 15, 2019 (HealthDay News) — From 2014 to 2017, there was an increase in physician burnout, with early-career physicians being the most susceptible, according to a study published online March 15 in JAMA Network Open.

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Extra Weight in Adolescence Tied to Later Risk for Renal Cancer

FRIDAY, March 15, 2019 (HealthDay News) — Overweight and obesity in adolescence is associated with an increased risk for developing renal cell carcinoma (RCC) later in life, according to a study published online Feb. 20 in the International Journal of Cancer.

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Induction for Late-Term Pregnancies at 41 Weeks Tied to Small Benefits

FRIDAY, March 15, 2019 (HealthDay News) — There may be a small benefit to labor induction in low-risk woman at 41 weeks versus expectant management, though the chances of a good perinatal outcome are high with both strategies, according to a study published online Feb. 20 in The BMJ.

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Mental Health Issues Have Risen in Teens, Young Adults

FRIDAY, March 15, 2019 (HealthDay News) — There has been a steady rise in mood disorder and suicide-related outcomes among individuals born from the early 1980s to the late 1990s, according to a study published March 14 in the Journal of Abnormal Psychology.

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Average of 283,000 Children Have Sports-Related TBIs/Year

THURSDAY, March 14, 2019 (HealthDay News) — Annually, an average of 283,000 children aged younger than 18 years seek care in emergency departments for sports- and recreation-related traumatic brain injuries (SRR-TBIs), according to research published in the March 15 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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AAP: Nasal Spray Vaccine Against Flu Acceptable in 2019 to 2020

THURSDAY, March 14, 2019 (HealthDay News) — The American Academy of Pediatrics (AAP) plans to advise families to vaccinate children against influenza with either the flu shot or nasal spray vaccine during the 2019 to 2020 flu season, in contrast to the academy’s preference for the injected vaccine over the nasal spray during the previous two flu seasons, the AAP announced today.

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E-Cigarettes May Threaten Goal of Achieving Tobacco Endgame

THURSDAY, March 14, 2019 (HealthDay News) — There is considerable concern regarding the potential negative impact that electronic cigarettes and other new products may have on ending all tobacco use and nicotine addiction, according to a presidential advisory issued by the American Heart Association and published online March 13 in Circulation.

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Prenatal High-Dose Vitamin D Not Linked to Asthma at Age 6

THURSDAY, March 14, 2019 (HealthDay News) — High-dose vitamin D supplementation in pregnancy is not associated with a child’s risk for asthma at age 6 years, according to a research letter published in the March 12 issue of the Journal of the American Medical Association.

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Mumps Causes Quarantine of Over 2,200 Immigrant Detainees

WEDNESDAY, March 13, 2019 (HealthDay News) — More than 2,200 people exposed to a mumps outbreak in two U.S. immigrant detention facilities have been quarantined, federal officials say.

AP News Article
More Information: CDC

Head of National Cancer Institute Named Acting FDA Commissioner

WEDNESDAY, March 13, 2019 (HealthDay News) — The U.S. Food and Drug Administration will temporarily be overseen by the head of the National Cancer Institute when FDA Commissioner Scott Gottlieb, M.D., leaves the post next month.

AP News Article

Bronchiolitis Hospitalization in Infancy Predicts More Admissions

WEDNESDAY, March 13, 2019 (HealthDay News) — More than one in five infants with a bronchiolitis hospital admission will have a subsequent respiratory-related hospital admission by age 5 years, according to a study published online March 6 in the Archives of Disease in Childhood.

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CDC: Most Americans Report Excellent, Good Health

WEDNESDAY, March 13, 2019 (HealthDay News) — Most Americans report having excellent or good health and have a usual place to go for medical care, according to a report published March 13 for the National Health Interview Survey Early Release Program.

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Homes With High Ventilation Rates Tied to Respiratory Issues

WEDNESDAY, March 13, 2019 (HealthDay News) — People living in homes with high average air exchange rates (AAERs) are more likely to report chronic cough, asthma, or asthma-like symptoms, according to a study published in the February issue of Environmental Research.

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CDC: 228 Measles Cases Already in 2019

TUESDAY, March 12, 2019 (HealthDay News) — The number of measles cases in the United States increased by 22 since last week and now stands at 228, the U.S. Centers for Disease Control and Prevention says in an update.

CNN Article
More Information: CDC

Parent Perception of E-Cig Safety Varies With Smoking Habits

TUESDAY, March 12, 2019 (HealthDay News) — Parents who both smoke cigarettes and electronic cigarettes are less likely to have smoke-free car and vape-free car or home policies compared with cigarette users, according to a study published online March 11 in Pediatrics.

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CDC: Flu Season May Have Peaked

MONDAY, March 11, 2019 (HealthDay News) — It looks like the flu season has peaked in the United States, though there has been a recent rise in the number of cases involving a more severe flu strain.

AP News Article
More Information: CDC

Children With Poorly Controlled Asthma Suffer Academically

MONDAY, March 11, 2019 (HealthDay News) — Urban children with asthma, particularly those who are ethnic minorities, have more school absences than their peers without asthma, according to a study published online March 11 in the Annals of Allergy, Asthma, & Immunology.

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Sudden Unexpected Infant Death Up With Maternal Smoking

MONDAY, March 11, 2019 (HealthDay News) — The risk for sudden unexpected infant death (SUID) is increased with any maternal smoking during pregnancy, according to a study published online March 11 in Pediatrics.

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Patterns of Joint Behavior Useful for Juvenile Arthritis Classification

MONDAY, March 11, 2019 (HealthDay News) — An algorithm that can classify patients with juvenile idiopathic arthritis (JIA) into seven distinct groups based on patterns of swollen or painful joints in the body can help predict disease course, according to a study published online Feb. 26 in PLOS Medicine.

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Mumps Outbreak Reported at Temple University

FRIDAY, March 8, 2019 (HealthDay News) — Ten confirmed cases of mumps, six probable cases, and a case under investigation have been reported at Temple University in Philadelphia.

CNN Article
More Information: CDC

Dasotraline Promising for the Treatment of ADHD in Children

FRIDAY, March 8, 2019 (HealthDay News) — Treatment with dasotraline (4 mg/day) significantly improves attention-deficit/hyperactivity disorder (ADHD) symptoms in children aged 6 to 12 years, according to a study published online March 7 in the Journal of Child and Adolescent Psychopharmacology.

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CDC: GI, Respiratory Illnesses More Likely in Low-Income Children

THURSDAY, March 7, 2019 (HealthDay News) — Children from lower-income households are more likely to report recent childhood gastrointestinal and respiratory illnesses but are less likely to miss any school days, according to research published in the March 8 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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No Increased Risk Seen for Pregnancies Conceived Within Year of Stillbirth

WEDNESDAY, March 6, 2019 (HealthDay News) — Conception within 12 months of a stillbirth is common and is not associated with an increased risk for adverse pregnancy outcomes, according to a study published online Feb. 28 in The Lancet.

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AAP: Social Media Companies Must Curb Spread of Vaccine Myths

TUESDAY, March 5, 2019 (HealthDay News) — Google, Facebook, and Pinterest need to take more action against the growing threat to children posed by online misinformation about vaccines, the American Academy of Pediatrics said in a letter sent to the social media companies.

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FDA Commissioner Dr. Scott Gottlieb Resigns

TUESDAY, March 5, 2019 (HealthDay News) — In what probably came as a surprise to many, U.S. Food and Drug Administration Commissioner Scott Gottlieb, M.D., announced his resignation on Tuesday. Gottlieb is leaving the FDA because he wants to spend more time with his wife and three young daughters — twins aged 9 and a 5-year-old — one official said. He currently commutes each week from the family home in Connecticut to his Washington, D.C., office.

The Washington Post Article

Children With Atopic Dermatitis Have Worse Sleep Quality

TUESDAY, March 5, 2019 (HealthDay News) — Children with atopic dermatitis (AD) have worse sleep quality, according to a study published online March 4 in JAMA Pediatrics.

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Program in Peds Rheumatology Clinic Ups Education on Teratogenic Rx

TUESDAY, March 5, 2019 (HealthDay News) — A series of interventions introduced through a quality improvement project can increase the frequency of both teratogen education and urine pregnancy screening in patients taking teratogenic medications for rheumatic disease, according to a study published online March 5 in Pediatrics.

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Childhood Cancer Considerably Underdiagnosed Worldwide

TUESDAY, March 5, 2019 (HealthDay News) — There is considerable underdiagnosis of childhood cancer, especially in south Asia and areas of Africa, according to a study published online Feb. 26 in The Lancet Oncology.

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Peanut Patch Linked to Increased Responder Rate in Children

TUESDAY, March 5, 2019 (HealthDay News) — For peanut-allergic children, use of epicutaneous immunotherapy with a peanut patch is associated with a statistically significant increase in the percentage of responders (meeting a defined eliciting dose to a peanut challenge) at 12 months, according to a study published online Feb. 22 in the Journal of the American Medical Association.

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Editorial

MMR Not Linked to Autism in Danish Cohort Study

MONDAY, March 4, 2019 (HealthDay News) — Measles, mumps, rubella (MMR) vaccination is not associated with an increased risk for autism, including in children with autism risk factors, according to a study published online March 5 in the Annals of Internal Medicine.

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Multidimensional Approach Cuts Unneeded Drug-Drug Interaction Alerts

MONDAY, March 4, 2019 (HealthDay News) — An iterative, multidimensional quality improvement (QI) effort can reduce interruptive drug-drug interaction (DDI) alerts, according to a study published in the March issue of Pediatrics.

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FDA Warns Americans Not to Buy Drugs From Canadian Company

FRIDAY, March 1, 2019 (HealthDay News) — A large Canadian drug distributor sells unapproved and mislabeled medicines to Americans, the U.S. Food and Drug Administration warned Thursday. The distributor disputes the claim, however.

The New York Times Article
More Information: FDA

Electronic Decision Support Tool Can Aid Asthma Care

FRIDAY, March 1, 2019 (HealthDay News) — A new electronic decision support tool can improve the quality of asthma care in primary care settings, according to a study published online Feb. 14 in the European Respiratory Journal.

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New York City Measles Outbreak Cases Reach 121

FRIDAY, March 1, 2019 (HealthDay News) — The number of measles cases in the New York City outbreak that began last October in the Orthodox Jewish community has reached 121, the city’s health department said Thursday.

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Wireless Sensor System Feasible for Monitoring Vital Signs in NICU

FRIDAY, March 1, 2019 (HealthDay News) — Wireless epidermal electronic systems with in-sensor analytics are feasible for use in the neonatal intensive care unit (NICU), according to a study published in the March 1 issue of Science.

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Editorial

Long-Term Cardiomyopathy Risk Varies by Chemo Agent

FRIDAY, March 1, 2019 (HealthDay News) — Long-term cardiomyopathy risk varies by chemotherapy agent for childhood cancer survivors, with a decreased risk for daunorubicin versus doxorubicin, according to a study recently published in JAMA Oncology.

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HPV Infection Unlikely to Spread From Hand Contact

FRIDAY, March 1, 2019 (HealthDay News) — The majority of genital human papillomavirus (HPV) infections are likely to be caused by genital-to-genital sexual transmission, not hand-to-genital contact, according to a study published online Feb. 8 in The Lancet Infectious Diseases.

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