Here are what the editors at HealthDay consider to be the most important developments in Psychiatry for March 2019. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

High Prenatal Omega-6:Omega-3 Ratio Linked to ADHD at Age 7

FRIDAY, March 29, 2019 (HealthDay News) — A higher prenatal omega-6:omega-3 long chain polyunsaturated fatty acid ratio in cord plasma is associated with a higher attention-deficit/hyperactivity disorder (ADHD) index score for the child at age 7 years, according to a study published online March 28 in The Journal of Pediatrics.

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Questions Remain About Safety of Parkinson Disease Psychosis Drug

FRIDAY, March 29, 2019 (HealthDay News) — There are many unanswered questions about the safety and effectiveness of a drug used to combat hallucinations and delusions in Parkinson disease patients, says a report from a drug safety group. The nonprofit Institute for Safe Medication Practices (ISMP) called for Nuplazid to have stronger warnings on its label for patients and their families, CNN reported.

CNN Article

Recommendations Presented on Genetic Testing in Psychiatry

FRIDAY, March 29, 2019 (HealthDay News) — Recommendations have been developed for the use of genetic testing in psychiatric care, according to a statement published by the International Society of Psychiatric Genetics (ISPG).

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Doctors With Malpractice Claims More Likely to Leave Medicine

THURSDAY, March 28, 2019 (HealthDay News) — Physicians with one or more paid malpractice claims are more likely to leave practice or shift into smaller practice settings, according to a study published in the March 28 issue of the New England Journal of Medicine.

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Nonsurgical Brain Stimulation Beneficial in Major Depressive Episodes

THURSDAY, March 28, 2019 (HealthDay News) — Nonsurgical brain stimulation techniques seem effective for acute treatment of major depressive episodes in adults, according to a review published online March 27 in The BMJ.

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Maltreatment in Childhood May Affect Course of Adult Depression

WEDNESDAY, March 27, 2019 (HealthDay News) — Early life stress caused by childhood maltreatment can alter brain structure, which may increase the risk for adverse disease courses in patients with major depression, according to a study published in the April issue of The Lancet Psychiatry.

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Douglas County, Colorado, Ranked as Healthiest Community

TUESDAY, March 26, 2019 (HealthDay News) — The 2019 healthiest community in America is Douglas County, Colorado, according to a report published online March 26 by U.S. News & World Report, in conjunction with the Aetna Foundation.

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Smoking Seems Not to Be Linked to Increased Dementia Risk

TUESDAY, March 26, 2019 (HealthDay News) — After adjusting for the competing risk of death without dementia, smoking is not associated with an increased risk for dementia, according to a study published online March 26 in the Journal of Alzheimer’s Disease.

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Digital Intervention Ups Socialization in Children With Autism

MONDAY, March 25, 2019 (HealthDay News) — An artificial intelligence-driven wearable behavioral intervention, Superpower Glass, can improve social outcomes for children with autism spectrum disorder (ASD), according to a study published online March 25 in JAMA Pediatrics.

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2019 Residency Match Day Was Largest in History

MONDAY, March 25, 2019 (HealthDay News) — The 2019 Main Residency Match was the largest in history, with a record high of 38,376 applicants for 35,185 positions, according to 2019 Match Day results released by the National Resident Matching Program.

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Stricter Gun Laws Tied to Safer High Schools

FRIDAY, March 22, 2019 (HealthDay News) — The adoption of stricter state gun laws is associated with improvements in school climate, including fewer students carrying weapons, according to a study published online March 21 in the Journal of Epidemiology & Community Health.

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Prenatal Pesticide Exposure Linked to Increased Risk for Autism

FRIDAY, March 22, 2019 (HealthDay News) — Prenatal exposure to ambient pesticides within 2,000 m of maternal residence during pregnancy is associated with an increased risk for autism spectrum disorder, according to a study published online March 20 in The BMJ.

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Many Patients Still Employ Strategies to Reduce Prescription Drug Costs

FRIDAY, March 22, 2019 (HealthDay News) — The number of adults reporting the use of strategies, such as requesting a lower-cost medication or not using medication as prescribed, to reduce prescription drug costs remained stable in 2015 to 2017, according to a March data brief published by the U.S. Centers for Disease Control and Prevention National Center for Health Statistics.

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Recent Increase Reported in Drug Overdose Deaths Involving Fentanyl

THURSDAY, March 21, 2019 (HealthDay News) — From 2011 to 2016, there was an increase in drug overdose deaths involving fentanyl, according to the March 21 National Vital Statistics Reports, a publication from the U.S. Centers for Disease Control and Prevention.

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In Youth With ADHD, New-Onset Psychosis Up With Amphetamines

THURSDAY, March 21, 2019 (HealthDay News) — For adolescents and young adults with attention-deficit/hyperactivity disorder (ADHD), new-onset psychosis occurs more often with amphetamine use versus methylphenidate use, according to a study published in the March 21 issue of the New England Journal of Medicine.

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Three Factors Predict Psych Events With Drugs for Smoking Cessation

THURSDAY, March 21, 2019 (HealthDay News) — Three factors predict clinically significant neuropsychiatric adverse events (NPSAEs) in smokers with or without mental health conditions who use cessation pharmacotherapy, according to a study published online March 7 in the Journal of General Internal Medicine.

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Antiepileptic Drugs Not Tied to Dementia Risk

WEDNESDAY, March 20, 2019 (HealthDay News) — Antiepileptic drug (AED) use is not significantly associated with dementia risk in patients in Germany, according to a study published online March 12 in the Journal of Alzheimer’s Disease.

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Daily Cannabis Use May Up Risk for Developing Psychotic Disorder

WEDNESDAY, March 20, 2019 (HealthDay News) — Cannabis use is associated with increased odds of psychotic disorder, according to a study published online March 19 in The Lancet Psychiatry.

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FDA: First Treatment Approved Specifically for Postpartum Depression

WEDNESDAY, March 20, 2019 (HealthDay News) — Zulresso (brexanolone) injection has been approved for intravenous (IV) use in the treatment of postpartum depression (PPD) in adult women, marking the first drug approved specifically for PPD, the U.S. Food and Drug Administration announced yesterday.

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Overall, Physicians Are Happy and Enjoy Their Lives

WEDNESDAY, March 20, 2019 (HealthDay News) — Overall, physicians are happy and enjoy their lives, according to the 2019 American Academy of Family Physicians (AAFP)/CompHealth Physician Happiness Survey published online March 19.

2019 AAFP/CompHealth Physician Happiness Survey

2011 to 2015 Saw Increase in Psychiatric ED Visits for Youth

MONDAY, March 18, 2019 (HealthDay News) — From 2011 to 2015, there was an increase in visits to the emergency department for psychiatric purposes among youth across the United States, according to a study published online March 18 in Pediatrics.

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Average of 8.8 Inactive Ingredients Found in Oral Medications

MONDAY, March 18, 2019 (HealthDay News) — Oral forms of medications contain an average of 8.8 inactive ingredients, many of which could cause adverse reactions, according to a perspective piece published in the March 13 issue of Science Translational Medicine.

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Physician Burnout Rate Increased From 2014 to 2017

FRIDAY, March 15, 2019 (HealthDay News) — From 2014 to 2017, there was an increase in physician burnout, with early-career physicians being the most susceptible, according to a study published online March 15 in JAMA Network Open.

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Mental Health Issues Have Risen in Teens, Young Adults

FRIDAY, March 15, 2019 (HealthDay News) — There has been a steady rise in mood disorder and suicide-related outcomes among individuals born from the early 1980s to the late 1990s, according to a study published March 14 in the Journal of Abnormal Psychology.

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E-Cigarettes May Threaten Goal of Achieving Tobacco Endgame

THURSDAY, March 14, 2019 (HealthDay News) — There is considerable concern regarding the potential negative impact that electronic cigarettes and other new products may have on ending all tobacco use and nicotine addiction, according to a presidential advisory issued by the American Heart Association and published online March 13 in Circulation.

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CDC: 2000 to 2017 Saw Increase in Mortality Due to Dementia

THURSDAY, March 14, 2019 (HealthDay News) — Mortality attributed to dementia increased from 2000 to 2017, with variation by age, race, and sex, according to a study published online March 14 in National Vital Statistics Reports, a publication from the U.S. Centers for Disease Control and Prevention.

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Head of National Cancer Institute Named Acting FDA Commissioner

WEDNESDAY, March 13, 2019 (HealthDay News) — The U.S. Food and Drug Administration will temporarily be overseen by the head of the National Cancer Institute when FDA Commissioner Scott Gottlieb, M.D., leaves the post next month.

AP News Article

Prediagnosis Psychiatric Care Linked to Worse Cancer Mortality

WEDNESDAY, March 13, 2019 (HealthDay News) — Precancer psychiatric utilization (PU) is associated with worse cancer-specific mortality (CSM) and all-cause mortality (ACM) among adults with solid organ malignancies, according to a study recently published in the British Journal of Cancer.

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CDC: Most Americans Report Excellent, Good Health

WEDNESDAY, March 13, 2019 (HealthDay News) — Most Americans report having excellent or good health and have a usual place to go for medical care, according to a report published March 13 for the National Health Interview Survey Early Release Program.

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Acupressure Reduces Lasting Symptoms in Breast Cancer Survivors

TUESDAY, March 12, 2019 (HealthDay News) — Acupressure is associated with improvements in co-occurring symptoms in breast cancer survivors with fatigue, according to a study recently published in JNCI Cancer Spectrum.

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Dual Receipt of Opioids Tied to Increased Risk for OD Death

MONDAY, March 11, 2019 (HealthDay News) — For veterans enrolled in the U.S. Department of Veterans Affairs (VA) and Medicare Part D, receipt of opioids from both VA and Part D is associated with an increased likelihood of death from prescription opioid overdose, according to a study published online March 12 in the Annals of Internal Medicine.

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Anxiety, Depression More Likely for Adults With Atopic Dermatitis

MONDAY, March 11, 2019 (HealthDay News) — Atopic dermatitis (AD) is associated with increased depression and anxiety, according to a study published online March 5 in the British Journal of Dermatology.

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Dasotraline Promising for the Treatment of ADHD in Children

FRIDAY, March 8, 2019 (HealthDay News) — Treatment with dasotraline (4 mg/day) significantly improves attention-deficit/hyperactivity disorder (ADHD) symptoms in children aged 6 to 12 years, according to a study published online March 7 in the Journal of Child and Adolescent Psychopharmacology.

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FDA Approves Ketamine-Like Drug for Severe Depression

WEDNESDAY, March 6, 2019 (HealthDay News) — The U.S. Food and Drug Administration on Tuesday approved the nasal spray medication esketamine — a relative of the club drug and anesthetic ketamine — for use against severe depression. Sold as Spravato, the fast-acting drug becomes the first new type of medicine approved in years against an illness that affects millions of Americans.

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Few Seniors Receive Regular Brief Cognitive Assessments

WEDNESDAY, March 6, 2019 (HealthDay News) — Only 16 percent of seniors receive regular cognitive assessments, according to the Alzheimer’s Disease Facts and Figures report published March 5.

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Mental Health Symptoms Common After Mild Brain Injury

WEDNESDAY, March 6, 2019 (HealthDay News) — Approximately one in five individuals may develop mental health symptoms up to six months after mild traumatic brain injury (mTBI), according to a study recently published in JAMA Psychiatry.

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Studies Look at Ways to Reduce Depressive Episodes in Obese

TUESDAY, March 5, 2019 (HealthDay News) — For overweight adults with depression, daily multinutrient supplements and individual or group therapy sessions do not reduce major depressive disorder (MDD) episodes over one year, but an integrated intervention appears to be beneficial, according to two studies published in the March 5 issue of the Journal of the American Medical Association.

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FDA Commissioner Dr. Scott Gottlieb Resigns

TUESDAY, March 5, 2019 (HealthDay News) — In what probably came as a surprise to many, U.S. Food and Drug Administration Commissioner Scott Gottlieb, M.D., announced his resignation on Tuesday. Gottlieb is leaving the FDA because he wants to spend more time with his wife and three young daughters — twins aged 9 and a 5-year-old — one official said. He currently commutes each week from the family home in Connecticut to his Washington, D.C., office.

The Washington Post Article

MMR Not Linked to Autism in Danish Cohort Study

MONDAY, March 4, 2019 (HealthDay News) — Measles, mumps, rubella (MMR) vaccination is not associated with an increased risk for autism, including in children with autism risk factors, according to a study published online March 5 in the Annals of Internal Medicine.

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Poll: Many Older Adults Report Feeling Lonely, Isolated

MONDAY, March 4, 2019 (HealthDay News) — Many older adults, especially those with health issues, report feeling lonely and isolated, according to the results of the National Poll on Healthy Aging, published on March 4.

National Poll on Healthy Aging

Multidimensional Approach Cuts Unneeded Drug-Drug Interaction Alerts

MONDAY, March 4, 2019 (HealthDay News) — An iterative, multidimensional quality improvement (QI) effort can reduce interruptive drug-drug interaction (DDI) alerts, according to a study published in the March issue of Pediatrics.

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FDA Warns Americans Not to Buy Drugs From Canadian Company

FRIDAY, March 1, 2019 (HealthDay News) — A large Canadian drug distributor sells unapproved and mislabeled medicines to Americans, the U.S. Food and Drug Administration warned Thursday. The distributor disputes the claim, however.

The New York Times Article
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Drivers’ Opioid Use Associated With Fatal Car Crashes

FRIDAY, March 1, 2019 (HealthDay News) — Drivers’ use of prescription opioids is associated with initiation of fatal two-vehicle crashes independent of alcohol use, according to a study published online Feb. 15 in JAMA Network Open.

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Heavy Smoking Linked to Damaged Spatial, Color Vision

FRIDAY, March 1, 2019 (HealthDay News) — Heavy smoking is associated with damaged vision, according to a study published in the January issue of Psychiatry Research.

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