This study aimed to investigate the relationship between marital status and the prognosis of patients with UTUC treated with NU.

Patients with UTUC who received NU treatment were identified from the SEER database. Kaplan–Meier curves and Cox regression were used to analyzing the effect of marital status on CSS, and 1:1 PSM was performed for married and unmarried patients to explore further the impact of marital status on patients with UTUC.

One thousand five hundred sixty-five patients were eligible, 960 were married, and 605 were unmarried, of which 146 were divorced/separated, 306 were widowed, and 153 were single. Multivariate Cox regression analysis showed that marital status was not an independent risk factor for patients with UTUC treated with NU. After stratification by grade and SEER stage, multivariate analysis showed no significant difference in 5-year CSS between divorced/separated, widowed, and single patients compared with married patients in different grades and SEER stages. After PSM analysis, marital status was still not an independent risk factor for patients with UTUC treated with NU.

The study concluded that for patients with UTUC treated with NU, marital status has no prognostic effect on CSS.

Reference: https://journals.sagepub.com/doi/full/10.1177/1756287220981510