Here are what the editors at HealthDay consider to be the most important developments in Gastroenterology for May 2019. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Lupus Manifestations Appear to Differ by Race, Ethnicity

FRIDAY, May 31, 2019 (HealthDay News) — Clinical manifestations of systemic lupus erythematosus (SLE) vary by racial and ethnic groups, according to a study published online May 22 in Arthritis Care & Research.

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Excess Cause-Specific Mortality Tied to Chronic Proton Pump Inhibitor Use

FRIDAY, May 31, 2019 (HealthDay News) — Taking proton pump inhibitors (PPIs) is associated with an excess of cause-specific mortality, according to a study published online May 30 in The BMJ.

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Early-Onset CRC Rising Fastest for Whites in Western States

THURSDAY, May 30, 2019 (HealthDay News) — Whites in western states are experiencing the most rapid increase in early-onset colorectal cancer (CRC), according to a study published online May 29 in the Journal of the National Cancer Institute.

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High Costs Associated With Physician Burnout in U.S.

THURSDAY, May 30, 2019 (HealthDay News) — High costs are associated with physician turnover and reduced clinical hours attributed to burnout, according to a study published online May 28 in the Annals of Internal Medicine.

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Reading Visit Notes May Improve Medication Management

WEDNESDAY, May 29, 2019 (HealthDay News) — Reading clinical notes can help patients to understand why medications are prescribed and improves medication adherence for some patients, according to a brief research report published online May 28 in the Annals of Internal Medicine.

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Global Burden of Serious Health-Related Suffering to Double by 2060

WEDNESDAY, May 29, 2019 (HealthDay News) — The global burden of serious health-related suffering is set to increase 47 percent by 2060, according to a study published online May 22 in The Lancet Global Health.

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Regulation of Intestinal Microbiota Beneficial for Anxiety

TUESDAY, May 28, 2019 (HealthDay News) — Regulation of the intestinal microbiota appears to be effective for improving anxiety symptoms, with nonprobiotic interventions performing better than probiotic interventions, according to a review published online May 17 in General Psychiatry.

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Cancer Consultation Low in Noncurable Pancreatic Adenocarcinoma

TUESDAY, May 28, 2019 (HealthDay News) — Many patients with noncurable pancreatic adenocarcinoma do not have a specialized cancer consultation and most do not receive cancer-directed therapy, according to a study published online May 27 in CMAJ, the journal of the Canadian Medical Association.

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T2DM Is Risk Factor for Liver Fibrosis Progression in NAFLD

FRIDAY, May 24, 2019 (HealthDay News) — Type 2 diabetes mellitus (T2DM) is a risk factor for progression of liver fibrosis in patients with nonalcoholic fatty liver disease (NAFLD), according to a study published online May 21 in the Journal of Gastroenterology and Hepatology.

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Statin Use With Colorectal Cancer Lowers Risk for Early Death

FRIDAY, May 24, 2019 (HealthDay News) — Use of statins before or after colorectal cancer (CRC) diagnosis is linked to a lower risk for premature death, from either cancer or other causes, according to a review published online May 8 in Cancer Medicine.

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Pediatricians Should Encourage Fish Consumption for Children

THURSDAY, May 23, 2019 (HealthDay News) — Fish and shellfish consumption should be encouraged for children, according to a technical report published online May 20 in Pediatrics.

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Suboptimal Diet Accounted for >80,000 Cancer Cases in 2015

WEDNESDAY, May 22, 2019 (HealthDay News) — In 2015, more than 80,000 cancer cases were associated with suboptimal diet in U.S. adults, according to a study published online May 22 in JNCI: Cancer Spectrum.

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Adverse Liver Outcomes Up With Diagnosis of NAFLD/NASH

WEDNESDAY, May 22, 2019 (HealthDay News) — The risks for cirrhosis and hepatocellular carcinoma (HCC) are increased for patients with a recorded diagnosis of nonalcoholic fatty liver disease (NAFLD)/nonalcoholic steatohepatitis (NASH), according to a study published online May 20 in BMC Medicine.

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Clinical Drug Diversion Costly to Health Care Organizations

TUESDAY, May 21, 2019 (HealthDay News) — U.S. health care organizations lost nearly $454 million due to clinical drug diversion in 2018, according to the 2019 Drug Diversion Digest, released by Protenus Inc.

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Cancer Screening Less Likely Among Current Smokers

FRIDAY, May 17, 2019 (HealthDay News) — Current smokers are less likely to receive guideline-concordant screening studies for breast, prostate, and colorectal cancer versus never smokers, according to a study published online May 17 in JAMA Network Open.

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Many Lives Could Be Saved if All Hospitals Had Grade A Rating

FRIDAY, May 17, 2019 (HealthDay News) — More than 50,000 lives could be saved if all hospitals had an avoidable death rate equivalent to “A” grade hospitals, according to an updated report prepared for The Leapfrog Institute.

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Private Insurers Pay 241 Percent of What Medicare Would Pay

FRIDAY, May 17, 2019 (HealthDay News) — Prices paid to hospitals for privately insured patients in 2017 averaged 241 percent of what Medicare would have paid, with wide variation in prices among states, according to a report published by the RAND Corporation.

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Colorectal Cancer Incidence Increasing in Younger Adults

FRIDAY, May 17, 2019 (HealthDay News) — Colorectal cancer incidence is increasing among young adults in certain high-income countries, according to a study published online May 16 in The Lancet Gastroenterology & Hepatology.

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Recs Updated for TB Screening, Treatment in Health Care Workers

THURSDAY, May 16, 2019 (HealthDay News) — Guidelines have been updated for screening and treatment for tuberculosis (TB) infection among health care personnel, according to research published in the May 17 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Tool Predicts Quality Measures After Ventral Hernia Repair

WEDNESDAY, May 15, 2019 (HealthDay News) — The Outcomes Reporting App for Clinical and Patient Engagement (ORACLE) tool can predict quality measures following ventral hernia repair (VHR) and facilitate preoperative surgeon-patient discussions, according to a study published online May 2 in the Journal of the American College of Surgeons.

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U.S. Prevalence of Alcoholic Fatty Liver Disease Stable at 4.7 Percent

TUESDAY, May 14, 2019 (HealthDay News) — The prevalence of alcoholic fatty liver disease (AFLD) has remained stable among U.S. adults, affecting 4.7 percent of adults in 2015 to 2016, according to a research letter published online May 7 in the Journal of the American Medical Association.

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Patients Find Note Reading Important for Health Management

MONDAY, May 13, 2019 (HealthDay News) — Patients find note reading important for their health management and are rarely troubled by what they read, according to a study published in the May issue of the Journal of Medical Internet Research.

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Higher Risk for Cancer, Mortality Seen With Pediatric-Onset IBD

MONDAY, May 13, 2019 (HealthDay News) — Individuals with pediatric-onset inflammatory bowel disease (pIBD) have an increased risk for cancer and mortality, according to a study published online May 9 in Alimentary Pharmacology & Therapeutics.

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CDC: Hepatitis A Virus Reports Increased in 2016 to 2018

FRIDAY, May 10, 2019 (HealthDay News) — From 2016 to 2018, there was an increase in reports of hepatitis A cases, according to research published in the May 10 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Health Professionals Supportive of Medicinal Cannabis

FRIDAY, May 10, 2019 (HealthDay News) — Health professionals are generally supportive of medicinal cannabis use but report a lack of knowledge about its use, according to a review published online May 6 in PLOS ONE.

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Rate of Ordering Cancer Screening Tests Decreases During Clinic Day

FRIDAY, May 10, 2019 (HealthDay News) — As the clinic day progresses, the rate of clinician ordering of breast and colorectal cancer screening tests decreases, according to a study published online May 10 in JAMA Network Open.

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Whole-Body MRI Accurate for Staging Colorectal Cancer, NSCLC

FRIDAY, May 10, 2019 (HealthDay News) — Whole-body magnetic resonance imaging (WB-MRI) could be a quicker alternative to multimodality staging of colorectal cancer and non-small cell lung cancer (NSCLC), according to two studies published online May 9 in The Lancet Gastroenterology & Hepatology and The Lancet Respiratory Medicine.

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Doctors Aware of Patient Difficulties Affording Medical Care

FRIDAY, May 10, 2019 (HealthDay News) — Physicians are aware of patients’ difficulty with affording medical care and consider out-of-pocket costs in their decision making, according to an article published in a supplement to the May 7 issue of the Annals of Internal Medicine.

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ACS Sets Goal to Cut Cancer Mortality 40 Percent by 2035

THURSDAY, May 9, 2019 (HealthDay News) — The American Cancer Society (ACS) has set a goal of a 40 percent reduction in overall cancer mortality by 2035, according to a study published online May 8 in CA: A Cancer Journal for Clinicians.

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2018 Saw More Employed Physicians Than Self-Employed

THURSDAY, May 9, 2019 (HealthDay News) — In 2018, employed physicians outnumbered self-employed physicians, according to a report from the American Medical Association (AMA).

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Fifteen Million Patients Will Need First-Course Chemo in 2040

THURSDAY, May 9, 2019 (HealthDay News) — An estimated 15.0 million patients will require first-course chemotherapy in 2040, with delivery requiring 100,000 cancer physicians, according to a study published online May 8 in The Lancet Oncology.

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Biomarker Test Predicts Mild, Serious IBD in Newly Diagnosed

THURSDAY, May 9, 2019 (HealthDay News) — A new test can predict the course of inflammatory bowel disease (IBD) in patients, according to a study published online April 27 in Gut.

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CDC: Uninsurance Levels Did Not Change Significantly in 2018

THURSDAY, May 9, 2019 (HealthDay News) — In 2018, the percentage of U.S. individuals who were uninsured was not significantly different from the numbers in 2017, although uninsurance increased among adults aged 45 to 64 years, according to a report published online May 9 by the U.S. Centers for Disease Control and Prevention National Center for Health Statistics.

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Risk for Cancer Increased in Men, Women With T2DM

THURSDAY, May 9, 2019 (HealthDay News) — Men and women with type 2 diabetes (T2D) have an increased risk for overall cancer and some site-specific cancers, according to a study published online May 9 in the Journal of Diabetes.

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Prices Will Soon Be Included in TV Drug Ads

WEDNESDAY, May 8, 2019 (HealthDay News) — In response to public demands for action to control drug costs, the top U.S. health official says TV advertisements for prescription drugs will soon have to include prices.

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In 2015 to 2016, 45.8 Percent of U.S. Population Used Rx Drugs

WEDNESDAY, May 8, 2019 (HealthDay News) — In 2015 to 2016, 45.8 percent of the U.S. population used prescription drugs within the past 30 days, according to a May data brief published by the U.S. Centers for Disease Control and Prevention National Center for Health Statistics (NCHS).

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Alcohol Consumption Per Capita Increasing Among Adults

WEDNESDAY, May 8, 2019 (HealthDay News) — Global goals for reducing alcohol use are unlikely to be achieved, with the global adult per-capita consumption projected to continue increasing to 2030, according to a study published online May 7 in The Lancet.

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Oral Aspirin Does Not Up FIT Test Sensitivity for ID’ing CRC

WEDNESDAY, May 8, 2019 (HealthDay News) — Administration of a single dose of oral aspirin prior to fecal immunochemical testing does not increase test sensitivity for detecting advanced colorectal neoplasms, according to a study published in the May 7 issue of the Journal of the American Medical Association.

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In Men, Low BMI Tied to Later Inflammatory Bowel Disease

TUESDAY, May 7, 2019 (HealthDay News) — Low body mass index (BMI) among men entering adult life is associated with an increased incidence of Crohn disease (CD) and ulcerative colitis (UC) up to 40 years later, according to a study published online April 23 in Scientific Reports.

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Efforts Needed to Ensure Publication of All Trials

TUESDAY, May 7, 2019 (HealthDay News) — Efforts are needed to ensure all completed large trials are reported, according to a research letter published online May 7 in the Annals of Internal Medicine.

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External Reference Pricing Could Cut Drug Costs in U.S.

TUESDAY, May 7, 2019 (HealthDay News) — The average price for single-source brand-name drugs is higher in the United States than in other countries, indicating that external reference pricing could reduce costs, according to a study published in the May issue of Health Affairs.

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FDA: French Soft Ripened Cheese Possibly Contaminated

MONDAY, May 6, 2019 (HealthDay News) — Consumers should not eat and retailers should not sell or serve l’Explorateur soft ripened cheese due to possible Listeria monocytogenes contamination, the U.S. Food and Drug Administration says.

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Cardiorespiratory Fitness Tied to Lower Risk for Lung Cancer, CRC

MONDAY, May 6, 2019 (HealthDay News) — Higher cardiorespiratory fitness (CRF) is associated with a lower risk for incident lung and colorectal cancer and with a lower risk for all-cause mortality among those diagnosed with lung and colorectal cancer, according to a study published online May 6 in Cancer.

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Implementing Surgical Safety Checklist Reduces Mortality

FRIDAY, May 3, 2019 (HealthDay News) — There has been a significant reduction in surgical mortality during the last decade in Scotland that is partially attributable to the implementation of the World Health Organization Surgical Safety Checklist, according to a study published online April 16 in the British Journal of Surgery.

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CDC: Foodborne Infections Increased From 2015 to 2018

FRIDAY, May 3, 2019 (HealthDay News) — From 2015 to 2018, the incidence of most foodborne infections increased, according to research published in the April 26 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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More Than Half of U.S. Adults Have Medical Financial Hardship

FRIDAY, May 3, 2019 (HealthDay News) — Medical financial hardship affects more than half of adults in the United States, according to a study published online May 1 in the Journal of General Internal Medicine.

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FDA Approves Mavyret for Children, Adolescents With Hep C

WEDNESDAY, May 1, 2019 (HealthDay News) — Mavyret (glecaprevir and pibrentasvir) tablets are now approved to treat all six genotypes of hepatitis C virus (HCV) in children ages 12 to 17 years, the U.S. Food and Drug Administration announced yesterday.

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Cognitive Function Does Not Predict Pediatric Bariatric Surgery Outcome

WEDNESDAY, May 1, 2019 (HealthDay News) — Youth with cognitive impairment or developmental disability (CI/DD) have weight-loss trajectories after bariatric surgery similar to those of their peers with typical cognitive function, according to a study published online in the May issue of Pediatrics.

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