Here are what the editors at HealthDay consider to be the most important developments in Neurology for May 2020. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Multiple Sclerosis Tied to Higher Risk for CVD, Cerebrovascular Disease

THURSDAY, May 28, 2020 (HealthDay News) — Multiple sclerosis (MS) is associated with an increased risk for cardiovascular and cerebrovascular disease that is not completely accounted for by traditional vascular risk factors, according to a study published online May 4 in JAMA Neurology.

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Tooth Loss More Prevalent in Adults With Chronic Disease

THURSDAY, May 28, 2020 (HealthDay News) — Adults with severe chronic disease or with fair or poor general health have a higher prevalence of edentulism and severe tooth loss, according to research published in the May 29 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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9.5 Percent Uninsured in U.S. From January Through June 2019

WEDNESDAY, May 27, 2020 (HealthDay News) — A total of 9.5 percent of persons were uninsured from January through June 2019, according to a report published online May 28 by the National Center for Health Statistics.

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Links Found Between Leaders of Medical Associations, Industry

THURSDAY, May 28, 2020 (HealthDay News) — There are extensive financial relationships between leaders of U.S. professional medical associations and industry, according to a study published online May 27 in The BMJ.

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Spirituality May Have Protective Effect on QOL for Stroke Survivors

THURSDAY, May 28, 2020 (HealthDay News) — High spirituality among stroke survivors may moderate the association between care partner depressive symptomatology and quality of life (QOL) for survivors and their care partners, according to a study published online May 26 in Circulation: Cardiovascular Quality and Outcomes.

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Outcomes Similar After TAVR in Bicuspid, Tricuspid Anatomy

WEDNESDAY, May 27, 2020 (HealthDay News) — All-cause mortality and stroke are comparable at 30 days and one year after transcatheter aortic valve replacement (TAVR) among patients with bicuspid and tricuspid valve stenosis, according to a study published online May 27 in JACC: Cardiovascular Interventions.

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Neurofilament Light Chain Levels Elevated After Repetitive TBI

WEDNESDAY, May 27, 2020 (HealthDay News) — Repetitive mild traumatic brain injuries (mTBI) are associated with elevated exosomal and plasma levels of neurofilament light (NfL) chain, according to a study published online May 27 in Neurology.

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CBT Offers Some Benefits in Adults With Dissociative Seizures

WEDNESDAY, May 25, 2020 (HealthDay News) — For adults with dissociative seizures, cognitive behavioral therapy plus standardized medical care is not associated with a reduced frequency of monthly seizures but does improve secondary outcomes, according to a study published in the June issue of The Lancet Psychiatry.

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Neuroimaging Features of COVID-19 Are Variable

WEDNESDAY, May 27, 2020 (HealthDay News) — Neuroimaging features of COVID-19 are variable among patients with acute neurological symptoms but are dominated by acute ischemic infarcts, according to a research letter published online May 21 in Radiology.

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Only One in Four U.S. Hospitals With ICUs Have Tele-ICU Services

WEDNESDAY, May 27, 2020 (HealthDay News) — In 2018, half of U.S. hospitals had the capacity to conduct telehealth-based outpatient visits, while only one in four had tele-intensive care unit (tele-ICU) capabilities, according to a research letter published online April 30 in the Annals of Internal Medicine.

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Clinical Genetic Testing for Autism Remains Very Low

FRIDAY, May 22, 2020 (HealthDay News) — Only 3 percent of patients with autism spectrum disorder (ASD) report having received all recommended clinical genetic testing, according to a research letter published online May 13 in JAMA Psychiatry.

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Rate of Stroke Low in Hospitalized Patients With COVID-19

THURSDAY, May 21, 2020 (HealthDay News) — The rate of imaging-confirmed stroke is low in hospitalized patients with COVID-19, but mortality is higher than in contemporary controls without COVID-19 and historical controls, according to a study published online May 20 in Stroke.

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Risk for Autism Spectrum Disorder Up With Affected Aunt, Uncle

THURSDAY, May 21, 2020 (HealthDay News) — The risk for autism spectrum disorder (ASD) is increased for children with an aunt or uncle with ASD, according to a study recently published in Biological Psychiatry.

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Plasma NfL Level Tied to Risk for Disability in Multiple Sclerosis

WEDNESDAY, May 20, 2020 (HealthDay News) — Elevated plasma neurofilament light chain (pNfL) levels are associated with an increased risk for reaching sustained disability worsening in multiple sclerosis (MS), according to a study published online May 20 in Neurology.

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Review Highlights Neuropsychiatric Presentations of COVID-19

WEDNESDAY, May 20, 2020 (HealthDay News) — COVID-19 may cause delirium in some patients, according to a review published online May 18 in The Lancet Psychiatry.

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Cord Blood Does Not Improve Socialization Skills in Autism

TUESDAY, May 19, 2020 (HealthDay News) — A single infusion of cord blood (CB) does not improve socialization skills or reduce autism symptoms among children with autism spectrum disorder (ASD), according to a study published online May 19 in The Journal of Pediatrics.

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28 Million-Plus Surgeries Could Be Canceled Due to COVID-19

TUESDAY, May 19, 2020 (HealthDay News) — Worldwide, more than 28 million elective surgeries could be canceled or postponed during the 12 weeks of peak disruption due to COVID-19, according to a study published online May 12 in the British Journal of Surgery.

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Spending on Primary Care Continues to Lag in the U.S.

TUESDAY, May 19, 2020 (HealthDay News) — Spending on inpatient services, specialty care, and prescriptions together accounted for about two-thirds of the increase in total U.S. health care spending from 2002 to 2016, according to a research letter published online May 18 in JAMA Internal Medicine.

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Higher Burden of Cardiovascular Risk Tied to Cognitive Decline

TUESDAY, May 19, 2020 (HealthDay News) — Higher cardiovascular risk burden is associated with cognitive decline and neurodegeneration, according to a study published in the May 26 issue of the Journal of the American College of Cardiology.

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Burnout Comparable Between Millennial, Gen X Residents, Fellows

TUESDAY, May 19, 2020 (HealthDay News) — Millennial and Generation X medical residents and fellows experience similar rates of burnout and have similar levels of empathy, according to a study published online May 5 in Academic Psychiatry.

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Sleep Problems in Infancy May Be Tied to Autism Diagnosis

MONDAY, May 18, 2020 (HealthDay News) — Sleep-onset problems in the first year of life may precede an autism spectrum disorder (ASD) diagnosis in children at higher risk for ASD, according to a study published online May 7 in The American Journal of Psychiatry.

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Co-Occurring Visual Impairment, Dementia Heighten Disability Risk

MONDAY, May 18, 2020 (HealthDay News) — Older adults with both dementia and self-reported visual impairment (VI) may be at higher risk for disability than adults with only one of these conditions, according to a study published online May 14 in JAMA Ophthalmology.

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Use of Imaging to Assess Stroke Down in Early COVID-19 Epoch

MONDAY, May 18, 2020 (HealthDay News) — From a prepandemic to early-pandemic epoch, there was a decrease in the use of imaging for the evaluation of stroke, according to a research letter published online May 8 in the New England Journal of Medicine.

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Most Physicians Have Seen False-Negative COVID-19 Test Results

MONDAY, May 18, 2020 (HealthDay News) — Most physicians believe they have seen false-negative results for a COVID-19 diagnostic test, according to the results of a recent survey.

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Cough May Not Appear in Young Children With COVID-19

MONDAY, May 18, 2020 (HealthDay News) — Young children with COVID-19 may not present with respiratory symptoms, according to a case report published online May 12 in Frontiers in Pediatrics.

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T2DM Linked to Worse Cognitive Performance After Stroke

FRIDAY, May 15, 2020 (HealthDay News) — In a stroke population, type 2 diabetes (T2D), but not impaired fasting glucose, is associated with worse cognitive performance, according to a study published online May 14 in Stroke.

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Autism in Childhood May Up Risk for Later Eating Disorders

FRIDAY, May 15, 2020 (HealthDay News) — Greater autistic social traits in childhood could be a risk factor for the development of disordered eating in adolescence, according to a study published online May 3 in the Journal of Child Psychology and Psychiatry.

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Abnormalities Detected on Brain MRI of COVID-19 Patients in ICU

THURSDAY, May 14, 2020 (HealthDay News) — Among patients with COVID-19 pneumonia in the intensive care unit (ICU) with neurological symptoms, 44 percent of those undergoing magnetic resonance imaging (MRI) have acute findings, according to a study published online May 8 in Radiology.

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Guidance Issued for Acute Large Vessel CVA During COVID-19 Pandemic

THURSDAY, May 14, 2020 (HealthDay News) — In a guidance statement from the Society of Vascular and Interventional Neurology, published online April 29 in Stroke, recommendations are presented for the management of acute ischemic large vessel occlusion stroke during the COVID-19 pandemic.

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Improvements Seen in Some Cognitive Domains With Aerobic Exercise

THURSDAY, May 14, 2020 (HealthDay News) — A six-month aerobic exercise intervention is associated with improvements in cognitive domains and cerebrovascular regulation among middle-aged and older adults, according to a study published online May 13 in Neurology.

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Olfactory Dysfunction Most Often Occurs by Third Day of COVID-19

TUESDAY, May 12, 2020 (HealthDay News) — Olfactory dysfunction (OD) occurs commonly, severely, and early in COVID-19 infection, according to a study published online May 5 in Otolaryngology-Head and Neck Surgery.

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Long-Term Flavonoid Intake Tied to Lower Alzheimer Risk

TUESDAY, May 12, 2020 (HealthDay News) — Higher long-term dietary intake of flavonoids is associated with lower risks for Alzheimer disease and related dementias (ADRD) in U.S. adults, according to a study published online April 22 in the American Journal of Clinical Nutrition.

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Severe Illness Reported in Some Children With COVID-19

TUESDAY, May 12, 2020 (HealthDay News) — Severe illness from COVID-19 infection occurs in some children, most of whom have significant preexisting comorbidities, according to a study published online May 11 in JAMA Pediatrics.

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More Head Impacts Up Risk for Death in NFL Players

MONDAY, May 11, 2020 (HealthDay News) — An increase in repetitive head impacts is associated with an increased hazard of death among National Football League (NFL) players, according to a study published online May 11 in JAMA Network Open.

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Residual Shunt After PFO Closure Linked to Higher Risk for Stroke

MONDAY, May 11, 2020 (HealthDay News) — The presence of a residual shunt after patent foramen ovale (PFO) closure is associated with an increased risk for recurrent stroke or transient ischemic attack (TIA), according to a study published online May 12 in the Annals of Internal Medicine.

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Incidence of Psych Morbidity Up With Spinal Cord Injury

FRIDAY, May 8, 2020 (HealthDay News) — Adults with traumatic spinal cord injuries (SCIs) have an increased incidence of psychological morbidities and multimorbidity, according to a study published in the May issue of Mayo Clinic Proceedings.

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Death and Disability From Stroke Down in United Kingdom

FRIDAY, May 8, 2020 (HealthDay News) — The risk for death and disability after a stroke fell significantly between 2000 and 2015 in the United Kingdom, according to a study recently published in PLOS Medicine.

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New York State Reports Cases of Pediatric Inflammatory Syndrome Tied to COVID-19

THURSDAY, May 7, 2020 (HealthDay News) — The New York State Department of Health issued an advisory on May 6 regarding cases of pediatric multisystem inflammatory syndrome potentially associated with COVID-19.

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Endovascular Thrombectomy Alone Noninferior in Ischemic Stroke

THURSDAY, May 7, 2020 (HealthDay News) — Endovascular thrombectomy alone is noninferior to endovascular thrombectomy preceded by intravenous alteplase for patients with acute ischemic stroke from large-vessel occlusion, according to a study published online May 6 in the New England Journal of Medicine.

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Cardio-Obstetrics Team Key to Managing CVD in Pregnancy

THURSDAY, May 7, 2020 (HealthDay News) — A cardio-obstetrics team is essential for management of cardiovascular disease during pregnancy, according to an American Heart Association scientific statement published online May 4 in Circulation.

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Microstructural Differences Detected on Brain MRI in PANS

THURSDAY, May 7, 2020 (HealthDay News) — Children with pediatric acute-onset neuropsychiatric syndrome (PANS) have cerebral microstructural differences in multiple brain structures, including the deep gray matter structures, according to a study published online May 4 in JAMA Network Open.

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Yoga + Medical Care Better for Episodic Migraines

WEDNESDAY, May 6, 2020 (HealthDay News) — Yoga plus medical care is better than medical therapy alone for the treatment of episodic migraines, according to a study published online May 6 in Neurology.

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Average of 11 Work Days Lost Due to Injury Per Person in U.S.

TUESDAY, May 5, 2020 (HealthDay News) — Nonfatal injuries are costly, with a per-person average of approximately 11 lost work days and a value of $1,560 per year in the United States, according to a study published online May 4 in Injury Prevention.

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More Rural Stroke Patients Now Treated at Certified Stroke Centers

TUESDAY, May 5, 2020 (HealthDay News) — In the last decade, there has been a shift toward care in certified stroke centers for rural residents with acute ischemic stroke and transient ischemic attack, according to a study published online May 4 in JAMA Neurology.

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High Alcohol Consumption May Be Causally Tied to Stroke, PAD

TUESDAY, May 5, 2020 (HealthDay News) — Higher alcohol consumption may be causally associated with an increased risk for stroke and peripheral artery disease, according to a study published online May 5 in Circulation: Genomic and Precision Medicine.

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Evolocumab Does Not Impact Cognition in Atherosclerotic CVD

MONDAY, May 4, 2020 (HealthDay News) — For patients with atherosclerotic cardiovascular disease and low-density lipoprotein cholesterol (LDL-C) ≥70 mg/dL or non-high-density cholesterol ≥100 mg/dL despite statin therapy, evolocumab has no impact on patient-reported cognitive function, according to a study published in the May 12 issue of the Journal of the American College of Cardiology.

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Sleep Apnea Tied to High Blood Glucose Levels Among Blacks

MONDAY, May 4, 2020 (HealthDay News) — Black Americans with severe sleep apnea are more likely to have high blood glucose levels, according to a study published online April 28 in the Journal of the American Heart Association.

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CV Outcomes Improved in Those With, Without Type 2 Diabetes

FRIDAY, May 1, 2020 (HealthDay News) — Cardiovascular outcomes have improved since the 1990s, especially for individuals with type 2 diabetes, according to a study published online April 30 in the Journal of Clinical Endocrinology & Metabolism.

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More Mental Health Visits Tied to Lower Rates of Youth Suicide

FRIDAY, May 1, 2020 (HealthDay News) — The odds of suicide decrease among youths who have more mental health visits, according to a study recently published in JAMA Pediatrics.

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Anosmia in COVID-19 Linked to Lower Risk for Admission

FRIDAY, May 1, 2020 (HealthDay News) — For patients with COVID-19, anosmia is strongly associated with a reduced likelihood of being admitted to the hospital, according to a study published online April 24 in the International Forum of Allergy & Rhinology.

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Vascular Stiffness Similar in E-, Combustible Cigarette Users

FRIDAY, May 1, 2020 (HealthDay News) — Electronic cigarette (e-cigarette) use with or without combustible cigarette use is associated with a similar elevation in the augmentation index compared with combustible cigarette use alone, according to a study published online April 29 in the Journal of the American Heart Association.

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