Nowadays, Symptomatic metastatic spinal disease is increasing continuously. Minimally invasive spinal surgery is a treatment method of the lower complications profiles. This study’s primary purpose was to evaluate the efficacy of Minimally Invasive Spine Surgery (MISS). The researchers would determine using percutaneous pedicle screw fixation without or with mini-decompression in managing symptomatic spinal metastases. They evaluated the data of 51 consecutive patients who underwent percutaneous pedicle screw fixation treatment to treat metastatic spinal disease. The patients received treatments in two different ways. For example, patients with pathological compression fractures and mechanical instability received PPSF, and patients with radiological and clinical metastatic spinal cord compression received an additional mini decompression. 

The study showed that 49 out of 51 patients received successful treatment with MISS. Six patients needed a mini-decompression, and 27 patients improved in KPS by at least 10 points. Only two patients of the 51 had a worsening of KPS due to other comorbidities. Thus, the study concluded that MISS using PPSF is a reproducible and safe technique to maintain or improve functional outcomes from the vast amount of patients suffering from spinal metastases. However, More researches are on the way in search of new results.