Molecular diagnosis has become an allergy instrument. It is mandatory to apply medical research to its borders in alleged idiopathic anaphylaxis. The current study evaluates how a variety of possible culprits complex to confirm can be identified through molecular diagnoses. The number of anaphylaxis labelled idiopathic can be reduced with the use of molecular diagnosis depending on the various geographical regions. Alpha-gal, omega-5-gliadin, Anisakis, proteins and oleosins have been classified as the most important allergens. In a high proportion of instances, the function of cofactors has been shown to be important. It should still be excluded from mast cell disorders.
Further molecular diagnostic testing is required for use in clinical practise in order to identify sensitization to allergens not well represented in current business tests.