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Noninvasive ventilation in stable hypercapnic COPD: what is the evidence?

Noninvasive ventilation in stable hypercapnic COPD: what is the evidence?
Author Information (click to view)

Duiverman ML,


Duiverman ML, (click to view)

Duiverman ML,

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ERJ open research 2018 04 094(2) pii 00012-2018
Abstract

Long-term noninvasive ventilation (NIV) to treat chronic hypercapnic respiratory failure is still controversial in severe chronic obstructive pulmonary disease (COPD) patients. However, with the introduction of high-intensity NIV, important benefits from this therapy have also been shown in COPD. In this review, the focus will be on the arguments for long-term NIV at home in patients with COPD. The rise of (high-intensity) NIV in COPD and the randomised controlled trials showing positive effects with this mode of ventilation will be discussed. Finally, the challenges that might be encountered (both in clinical practice and in research) in further optimising this therapy, monitoring and following patients, and selecting the patients who might benefit most will be reviewed.

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