Novel Glutamine Antagonist JHU395 Suppresses MYC-Driven Medulloblastoma Growth and Induces Apoptosis. - Physician's Weekly

About The Expert

Khoa Pham

From the Department of Pathology, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA (KP, CGE, EHR); Division of Pediatric Oncology, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA (MJM, HS, EHR); Johns Hopkins Drug Discovery, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA (JA, RR, BSS); Department of Neurology, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA (RR, BSS); and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA (CGE, EHR).

Micah J Maxwell

From the Department of Pathology, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA (KP, CGE, EHR); Division of Pediatric Oncology, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA (MJM, HS, EHR); Johns Hopkins Drug Discovery, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA (JA, RR, BSS); Department of Neurology, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA (RR, BSS); and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA (CGE, EHR).

Heather Sweeney

From the Department of Pathology, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA (KP, CGE, EHR); Division of Pediatric Oncology, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA (MJM, HS, EHR); Johns Hopkins Drug Discovery, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA (JA, RR, BSS); Department of Neurology, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA (RR, BSS); and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA (CGE, EHR).

Jesse Alt

From the Department of Pathology, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA (KP, CGE, EHR); Division of Pediatric Oncology, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA (MJM, HS, EHR); Johns Hopkins Drug Discovery, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA (JA, RR, BSS); Department of Neurology, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA (RR, BSS); and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA (CGE, EHR).

Rana Rais

From the Department of Pathology, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA (KP, CGE, EHR); Division of Pediatric Oncology, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA (MJM, HS, EHR); Johns Hopkins Drug Discovery, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA (JA, RR, BSS); Department of Neurology, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA (RR, BSS); and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA (CGE, EHR).

Charles G Eberhart

From the Department of Pathology, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA (KP, CGE, EHR); Division of Pediatric Oncology, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA (MJM, HS, EHR); Johns Hopkins Drug Discovery, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA (JA, RR, BSS); Department of Neurology, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA (RR, BSS); and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA (CGE, EHR).

Barbara S Slusher

From the Department of Pathology, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA (KP, CGE, EHR); Division of Pediatric Oncology, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA (MJM, HS, EHR); Johns Hopkins Drug Discovery, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA (JA, RR, BSS); Department of Neurology, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA (RR, BSS); and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA (CGE, EHR).

Eric H Raabe

From the Department of Pathology, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA (KP, CGE, EHR); Division of Pediatric Oncology, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA (MJM, HS, EHR); Johns Hopkins Drug Discovery, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA (JA, RR, BSS); Department of Neurology, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA (RR, BSS); and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA (CGE, EHR).

References

PubMed