Here are what the editors at HealthDay consider to be the most important developments in Cardiology for November 2018. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Presence of Antiphospholipid Antibodies Tied to First-Time MI

FRIDAY, Nov. 30, 2018 (HealthDay News) — There is a strong and independent association between the presence of antiphospholipid antibodies (aPLs) and first-time myocardial infarction (MI), according to a research letter published recently in the Annals of Internal Medicine.

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Family Functioning Does Not Impact Family Dinner, Diet Link

FRIDAY, Nov. 30, 2018 (HealthDay News) — Among adolescents and young adults, family dinner frequency is associated with healthful dietary intake, regardless of family functioning, according to a study published online Nov. 21 in JAMA Network Open.

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Teva Recalls Two Blood Pressure Medications

FRIDAY, Nov. 30, 2018 (HealthDay News) — All lots of amlodipine/valsartan and amlodipine/valsartan/hydrochlorothiazide combination blood pressure tablets have been recalled by Teva Pharmaceuticals due to higher-than-acceptable levels of a chemical that may cause cancer.

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Higher Cardiovascular Risk Seen With Psoriatic Arthritis

FRIDAY, Nov. 30, 2018 (HealthDay News) — Cardiovascular risk should be carefully evaluated in patients with psoriatic arthritis, according to a study published online Nov. 5 in the International Journal of Rheumatic Diseases.

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Care for Chronic Kidney Disease Varies Across VA Facilities

FRIDAY, Nov. 30, 2018 (HealthDay News) — For veterans with diabetes and concomitant chronic kidney disease (CKD), CKD care, including ordering laboratory tests and scheduling nephrology referrals, varies considerably by facility, according to a study published online Nov. 29 in the Clinical Journal of the American Society of Nephrology.

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Several Risk Factors More Strongly Linked to MI in Women

FRIDAY, Nov. 30, 2018 (HealthDay News) — The incidence of myocardial infarction (MI) is higher in men than women, but several risk factors are more strongly linked to MI in women, according to a study published online Nov. 7 in The BMJ.

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Climate Change Ups Heat Deaths, Especially Among Elderly

THURSDAY, Nov. 29, 2018 (HealthDay News) — Risk for heat-related disease and death is rising worldwide due to climate change, according to a report published online Nov. 28 in The Lancet.

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Persistent Back Pain Linked to Earlier Mortality in Older Women

THURSDAY, Nov. 29, 2018 (HealthDay News) — Frequent persistent back pain is associated with increased mortality in older women, according to a study recently published in the Journal of General Internal Medicine.

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Deep Learning Algorithm Detects Thoracic Pathologies on CXRs

THURSDAY, Nov. 29, 2018 (HealthDay News) — A deep learning algorithm, CheXNeXt, performs comparably to radiologists in detecting multiple thoracic pathologies in frontal-view chest radiographs, according to a study published online Nov. 20 in PLOS Medicine.

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Certain SGLT2 Inhibitors, GLP-1 RAs for T2DM Also Cut CV Risk

THURSDAY, Nov. 29, 2018 (HealthDay News) — Certain sodium-glucose cotransporter 2 (SGLT2) inhibitors and glucagon-like peptide 1 receptor agonists (GLP-1 RAs) demonstrate significant cardiovascular (CV) benefit and should be used for reducing CV risk in patients with type 2 diabetes (T2D) and atherosclerotic cardiovascular disease (ASCVD), according to a report of the American College of Cardiology Task Force on Expert Consensus Decision Pathways published online Nov. 26 in the Journal of the American College of Cardiology.

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Lower Mortality Seen for Cardiac Care at Top-Ranked Hospitals

WEDNESDAY, Nov. 28, 2018 (HealthDay News) — Compared with nonranked hospitals, top-ranked hospitals have lower 30-day mortality but similar or higher readmission rates for cardiovascular conditions, according to a study published online Nov. 28 in JAMA Cardiology.

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Healthy Lifestyle Tied to Less Atherosclerosis for Women

WEDNESDAY, Nov. 28, 2018 (HealthDay News) — A healthy lifestyle during midlife is associated with less subclinical atherosclerosis among women, according to a study published online Nov. 28 in the Journal of the American Heart Association.

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Men Should Avoid ‘Rhino’ Sexual Enhancement Products, FDA Says

TUESDAY, Nov. 27, 2018 (HealthDay News) — The U.S. Food and Drug Administration is warning men that “Rhino” products promising better sex may pose serious health risks.

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FDA to Update Medical Device Approvals Process

TUESDAY, Nov. 27, 2018 (HealthDay News) — A major update of the United States’ system for approving medical devices was announced yesterday by the Food and Drug Administration.

CBS/AP News Article
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Four Principles Underlie Patient and Family Partnership in Care

TUESDAY, Nov. 27, 2018 (HealthDay News) — Patient and family partnership in care should include treatment of patients and families with dignity and respect, their active engagement in all aspects of care, and their contribution to the improvement of health care systems and education of health care professionals, according to a position paper published online Nov. 27 in the Annals of Internal Medicine.

Position Paper
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Recommended Therapies for Polycythemia Vera Underused

TUESDAY, Nov. 27, 2018 (HealthDay News) — Among older patients with polycythemia vera (PV), therapeutic phlebotomy and hydroxyurea (HU) are associated with improved overall survival and decreased risk for thrombosis but are underused, according to a study recently published in Blood Advances.

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Vitamin D Levels Linked to Cardiorespiratory Fitness

TUESDAY, Nov. 27, 2018 (HealthDay News) — Serum vitamin D levels are associated with cardiorespiratory fitness (CRF), according to a study recently published in the European Journal of Preventive Cardiology.

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ACA Coverage Substantial, but Did Not Impact Labor Markets

MONDAY, Nov. 26, 2018 (HealthDay News) — Millions of workers gained insurance coverage under the Affordable Care Act (ACA) without adverse effects on labor markets, according to a report published by the Robert Wood Johnson Foundation and the Urban Institute.

Report: How Have Workers Fared Under the ACA?

ADT May Up Risk for Heart Failure in Prostate Cancer Patients

MONDAY, Nov. 26, 2018 (HealthDay News) — For patients with prostate cancer, androgen deprivation therapy is associated with an increased risk for heart failure, according to a study published online Nov. 7 in the Journal of Clinical Pharmacology.

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Arterial Stiffness May Predict Dementia Risk

WEDNESDAY, Nov. 21, 2018 (HealthDay News) — Arterial stiffness may predict dementia risk, independent of subclinical brain damage, according to a study recently published in the Journal of Alzheimer’s Disease.

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Smoke-Free Policies Linked to Lower Systolic Blood Pressure

WEDNESDAY, Nov. 21, 2018 (HealthDay News) — Smoke-free policies are associated with small reductions in blood pressure (BP), according to a study published online Nov. 21 in the Journal of the American Heart Association.

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Major Bleeding Up With Frailty in Acute MI Patients

TUESDAY, Nov. 20, 2018 (HealthDay News) — Frail acute myocardial infarction (AMI) patients are less likely to undergo cardiac catheterization and have an increased risk for bleeding, according to a study published in the Nov. 26 issue of JACC: Cardiovascular Interventions.

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Onset of Musculoskeletal Adverse Events Varies Between Statins

MONDAY, Nov. 19, 2018 (HealthDay News) — The onset of musculoskeletal adverse events (MAEs) during statin monotherapy is significantly faster with use of atorvastatin and rosuvastatin versus simvastatin, according to a study published online Nov. 7 in Pharmacology Research & Perspectives.

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Patient Outcomes Tied to Valve Replacement Volume

MONDAY, Nov. 19, 2018 (HealthDay News) — Hospitals with high caseloads of both surgical aortic valve replacement (SAVR) and transcatheter aortic valve replacement (TAVR) have the best outcomes, according to a study published online Oct. 31 in JAMA Cardiology.

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CDC: 8.8 Percent Uninsured in U.S. in First Half of 2018

FRIDAY, Nov. 16, 2018 (HealthDay News) — In the first six months of 2018, 8.8 percent of U.S. individuals of all ages were uninsured, which was not significantly different from 2017, according to a report published Nov. 15 by the U.S. Centers for Disease Control and Prevention National Center for Health Statistics.

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Name-Brand Medications Driving Spike in U.S. Drug Spending

THURSDAY, Nov. 15, 2018 (HealthDay News) — Rising drug spending in the United States is being fueled by expensive name-brand prescription medicines, a new study shows.

NBC News Article
Blue Cross Blue Shield Report

CDC: Many Americans May Have Prediabetes and Not Know It

THURSDAY, Nov. 15, 2018 (HealthDay News) — More than one-third of Americans have prediabetes, but 90 percent of them do not know they have it, medical experts say.

Do I Have Prediabetes
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No Age-Related Increase in BP for Yanomami Community

THURSDAY, Nov. 15, 2018 (HealthDay News) — The Amerindian Yanomami community, which has no exposure to Western lifestyle, has no age-associated rise in blood pressure (BP), according to a research letter published online Nov. 14 in JAMA Cardiology.

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Patient Experiences Shed Light on Diagnostic Errors

THURSDAY, Nov. 15, 2018 (HealthDay News) — Data from patient- and family-reported error narratives indicate that problems related to patient-physician interactions are major contributors to diagnostic errors, according to a study published in the November issue of Health Affairs.

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AMA to Collect Data on Suicide Among Doctors-in-Training

WEDNESDAY, Nov. 14, 2018 (HealthDay News) — By collecting data on suicides by medical students, residents, and fellows, the American Medical Association hopes to identify ways to reduce suicides among doctors-in-training. The data collection policy was approved at a meeting yesterday.

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Sudden Cardiac Death Rates Up in Blacks Versus Whites

WEDNESDAY, Nov. 14, 2018 (HealthDay News) — Sudden cardiac death (SCD) rates are significantly higher among black adults than white adults without a history of cardiovascular disease, according to a study published in the Nov. 13 issue of the Journal of the American College of Cardiology.

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Changes in Risk Indicators of MetS Severity Tied to T2DM Risk

WEDNESDAY, Nov. 14, 2018 (HealthDay News) — For patients with prediabetes who are randomly assigned to interventions, changes in risk indicators of metabolic syndrome (MetS) severity are associated with the risk for type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD), according to a study published in the November issue of Diabetes Care.

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Heart Disease Leading Cause of Death in Low-Income Counties

WEDNESDAY, Nov. 14, 2018 (HealthDay News) — The leading cause of death varies with income in the United States, with heart disease still the leading cause of death in low-income counties, according to a study published online Nov. 13 in the Annals of Internal Medicine.

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Progress Toward Goals in Global Health Is Slowing

FRIDAY, Nov. 9, 2018 (HealthDay News) — Global progress in health has slowed, and improvements in health have been unevenly distributed, according to a series of articles published in a special issue of The Lancet, highlighting the fact that global progress in health is not inevitable.

The Lancet – The Global Burden of Disease Study 2017

Recommendations Issued for Management of Bradycardia

FRIDAY, Nov. 9, 2018 (HealthDay News) — The American College of Cardiology, American Heart Association, and Heart Rhythm Society have released guidance for the evaluation and treatment of bradycardia and cardiac conduction disorders, according to a guideline, review, and executive summary published online Nov. 6 in the Journal of the American College of Cardiology.

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Executive Summary (subscription or payment may be required)

In Abdominal Aortic Aneurysm Repair, Curcumin Lacks Benefit

FRIDAY, Nov. 9, 2018 (HealthDay News) — When used perioperatively in elective abdominal aortic aneurysm repair, curcumin has no beneficial effect, according to a study published in the Oct. 29 issue of CMAJ, the journal of the Canadian Medical Association.

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In-Hospital Infection May Up Readmission After Stroke

THURSDAY, Nov. 8, 2018 (HealthDay News) — For patients with ischemic stroke, infection during stroke hospitalization is associated with increased odds of 30-day readmission, according to a study published online Nov. 1 in Stroke.

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hs-cTnI Can Rule Out Inducible Myocardial Ischemia in CAD

THURSDAY, Nov. 8, 2018 (HealthDay News) — For patients with stable coronary artery disease (CAD), very low levels of resting high-sensitivity cardiac troponin I (hs-cTnI) can rule out inducible myocardial ischemia, according to a study published online Nov. 6 in the Annals of Internal Medicine.

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HTN in Young Adulthood Linked to CVD Later in Life

WEDNESDAY, Nov. 7, 2018 (HealthDay News) — High blood pressure (BP) in early adulthood is associated with an increased risk for cardiovascular disease (CVD) later in life, according to two studies published in the Nov. 6 issue of the Journal of the American Medical Association.

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Medicaid Expansion Approved in Three Republican-Leaning States

WEDNESDAY, Nov. 7, 2018 (HealthDay News) — Hundreds of thousands more low-income Americans could get health insurance after voters in three Republican-leaning states approved Medicaid expansion in the midterm elections.

CNBC Article

Nonadherence, Discontinuation of Statins High in 1st Year of Rx

WEDNESDAY, Nov. 7, 2018 (HealthDay News) — First-year nonadherence and discontinuation are high among older adults prescribed statins, according to a study published online Nov. 7 in the British Journal of Clinical Pharmacology.

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Inhaled Nitrite Does Not Improve Exercise Capacity in HFpEF

TUESDAY, Nov. 6, 2018 (HealthDay News) — Administration of inhaled nitrite is not associated with improvement in exercise capacity compared with placebo among patients with heart failure with preserved ejection fraction (HFpEF), according to a study published in the Nov. 6 issue of the Journal of the American Medical Association.

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AHA: After 2007 Recs, Increase Seen in Infective Endocarditis

TUESDAY, Nov. 6, 2018 (HealthDay News) — Following the 2007 American Heart Association (AHA) update of recommendations for antibiotic prophylaxis (AP) to prevent infective endocarditis (IE), there has been a decrease in AP and an increase in IE incidence for high-risk individuals, according to a study published online Nov. 5 in the Journal of the American College of Cardiology. The research was published to coincide with the annual meeting of the American Heart Association, held from Nov. 10 to 12 in Chicago.

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Characteristics of Black AMI Patients Impact Mortality Rate

MONDAY, Nov. 5, 2018 (HealthDay News) — For patients with acute myocardial infarction (AMI), mortality rates differ based on characteristics associated with race, according to a study published online Nov. 2 in JAMA Network Open.

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Majority of Internists Still Have Financial Ties to Industry

MONDAY, Nov. 5, 2018 (HealthDay News) — A majority of internists still report financial ties to industry, according to a study published online Oct. 5 in the Journal of General Internal Medicine.

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Sign-Up Season Begins on HealthCare.gov

FRIDAY, Nov. 2, 2018 (HealthDay News) — The federal government website where Americans can sign up for health insurance under the Affordable Care Act is up and running, officials said yesterday.

AP News Article
HealthCare.gov

National Youth Obesity Rate at 15.8 Percent for 2016 to 2017

FRIDAY, Nov. 2, 2018 (HealthDay News) — In 2016 to 2017, the national obesity rate for youth ages 10 to 17 years was 15.8 percent, which was not statistically different from the 16.1 percent rate in 2016 alone, according to a report published by the Robert Wood Johnson Foundation.

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Earlier Vascular Access Seen in Insured Dialysis Patients

FRIDAY, Nov. 2, 2018 (HealthDay News) — Patients with Medicare or Medicaid are more likely than uninsured patients to use an arteriovenous fistula or graft by their fourth dialysis month, according to a study published online Nov. 1 in the Clinical Journal of the American Society of Nephrology.

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Age, Racial Disparities Seen in Hospitalization for Heart Failure

FRIDAY, Nov. 2, 2018 (HealthDay News) — For emergency department patients with heart failure, data reveal age and racial disparities in hospitalization rates, according to a study published in the November issue of the American Journal of Preventive Medicine.

Abstract/Full Text

Second Hypertension Drug Recalled Due to Contamination

THURSDAY, Nov. 1, 2018 (HealthDay News) — Another hypertension drug is being recalled due to contamination that could pose a cancer risk, the U.S. Food and Drug Administration says.

CNN Article
FDA Recall Alert

Plant-Based Diets Beneficial for Adults With Type 2 Diabetes

THURSDAY, Nov. 1, 2018 (HealthDay News) — For adults with type 2 diabetes, plant-based diets can improve psychological health, quality of life, hemoglobin A1c levels, and weight, according to a review published online Oct. 30 in BMJ Open Diabetes Research & Care.

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Financial Conflicts of Interest Prevalent Among CPG Authors

THURSDAY, Nov. 1, 2018 (HealthDay News) — There is a high prevalence of financial conflicts of interest among authors of clinical practice guidelines (CPGs) related to high-revenue medications and in gastroenterology, according to two research letters published online Oct. 29 in JAMA Internal Medicine.

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Home BP of 130/80 mm Hg ID’d as Threshold for Stage 1 HTN

THURSDAY, Nov. 1, 2018 (HealthDay News) — A home blood pressure (BP) reading of 130/80 mm Hg should be considered the threshold for stage 1 hypertension, according to a study published online Oct. 29 in Hypertension.

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