Here are what the editors at HealthDay consider to be the most important developments in Pediatrics for November 2019. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Three Meds Equal as Second-Line Therapy for Status Epilepticus

WEDNESDAY, Nov. 27, 2019 (HealthDay News) — Levetiracetam, fosphenytoin, and valproate are equally effective in children and adults for the treatment of benzodiazepine-refractory convulsive status epilepticus, according to a study published in the Nov. 28 issue of the New England Journal of Medicine.

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Antimicrobial Resistance Patterns Examined for Adult, Peds HAIs

WEDNESDAY, Nov. 27, 2019 (HealthDay News) — In two reports published online Nov. 25 in Infection Control & Hospital Epidemiology, authors present updated summaries of common pathogens and antimicrobial resistance patterns among health care-associated infections (HAIs) in adult and pediatric patients.

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Object-Related Aspiration Deaths Decreased Among Children

WEDNESDAY, Nov. 27, 2019 (HealthDay News) — From 1968 to 2017, there was a decrease in object-related aspiration deaths in children and adolescents, according to a research letter published in the Nov. 26 issue of the Journal of the American Medical Association.

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Household Environment Plays Role in MRSA Acquisition

WEDNESDAY, Nov. 27, 2019 (HealthDay News) — The household environment plays a key role in the acquisition of methicillin-resistant Staphylococcus aureus (MRSA) skin and soft tissue infection, according to a study published online Nov. 26 in The Lancet Infectious Diseases.

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Diet Pill, Laxative Use in Women Tied to Later Eating Disorder Dx

WEDNESDAY, Nov. 27, 2019 (HealthDay News) — Diet pill and laxative use for weight control are associated with increased odds of subsequent first eating disorder diagnosis, according to a study published online Nov. 21 in the American Journal of Public Health.

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Asthma Exacerbations May Worsen Pregnancy Outcomes

WEDNESDAY, Nov. 27, 2019 (HealthDay News) — For women with asthma, asthma exacerbation (AE) during pregnancy is associated with an increased risk for pregnancy complications, adverse perinatal outcomes, and early childhood respiratory disorders, according to a study published online Nov. 26 in the European Respiratory Journal.

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Exposure to Psychoactive Substances Up From 2000 to 2017

WEDNESDAY, Nov. 27, 2019 (HealthDay News) — From 2000 to 2017, the overall rate of exposure to psychoactive substances of natural origin increased, according to a study published online Nov. 25 in Clinical Toxicology.

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Death Toll in Samoa Measles Epidemic Reaches 25

TUESDAY, Nov. 26, 2019 (HealthDay News) — The death toll in a measles epidemic sweeping Samoa has reached 25, and all but one of the victims have been young children, an official said Monday.

AP News Article

Potentially Tainted Marijuana Sold in Colorado

TUESDAY, Nov. 26, 2019 (HealthDay News) — A warning about possibly contaminated and moldy recreational and medical marijuana has been issued by Colorado officials.

CNN Article

U.S. Life Expectancy Dropped Since 2014 for Working-Age Adults

TUESDAY, Nov. 26, 2019 (HealthDay News) — U.S. life expectancy increased from 1959 to 2016 but has been decreasing since 2014, according to research published in the Nov. 26 issue of the Journal of the American Medical Association.

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Peds Cardiac Surgical Outcomes Improved in Consortium

TUESDAY, Nov. 26, 2019 (HealthDay News) — Children’s hospitals participating in the Pediatric Cardiac Critical Care Consortium (PC4) have improved cardiac surgery outcomes, including a 24 percent reduction in in-hospital mortality, according to a study published in the Dec. 3 issue of the Journal of the American College of Cardiology.

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New Screening Criteria Help Better ID Retinopathy of Prematurity

TUESDAY, Nov. 26, 2019 (HealthDay News) — A new screening method accurately predicts retinopathy of prematurity (ROP) and reduces the number of infants undergoing eye exams, according to a study published online Nov. 14 in JAMA Ophthalmology.

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Nutritional Deficiencies ID’d in Teens After Bariatric Surgery

MONDAY, Nov. 25, 2019 (HealthDay News) — Teens who undergo bariatric surgery may be at increased risk for nutritional deficiencies years later, according to a study published online Nov. 6 in Clinical Gastroenterology and Hepatology.

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Most Toddlers Exceed Screen Time Guidelines

MONDAY, Nov. 25, 2019 (HealthDay News) — Most children aged 2 and 3 years do not meet screen time guidelines, and 26.7 percent of children have an increasing screen time trajectory from age 1 to 3 years, according to two reports published online Nov. 25 in JAMA Pediatrics.

Abstract/Full Text – Madigan (subscription or payment may be required)
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Polio Vaccines Causing Polio Cases

MONDAY, Nov. 25, 2019 (HealthDay News) — More children worldwide are being paralyzed by polio viruses from vaccines than from viruses in the wild, according to new data.

AP News Article
More Information: WHO

Maternal Efavirenz May Up Risk for Microcephaly Among Offspring

MONDAY, Nov. 25, 2019 (HealthDay News) — In utero exposure to efavirenz is associated with an increased risk for microcephaly among children who are HIV-exposed but uninfected, according to a study published online Nov. 15 in The Lancet HIV.

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Overall Rate of Pediatric Nonpowder Firearm Injuries Down

MONDAY, Nov. 25, 2019 (HealthDay News) — From 1990 to 2016, there was a decrease in nonpowder firearm injuries treated in emergency departments among children but an increase in the rate of eye injuries, according to a study published online Nov. 25 in Pediatrics.

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Most Teens Worldwide Are Not Exercising Enough

FRIDAY, Nov. 22, 2019 (HealthDay News) — The majority of adolescents worldwide do not meet current physical activity guidelines, according to a study published online Nov. 21 in The Lancet Child & Adolescent Health.

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Parental Marijuana Use Ups Risk for Substance Use in Offspring

FRIDAY, Nov. 22, 2019 (HealthDay News) — Parental marijuana use is associated with an increased risk for substance use among adolescent and young adult offspring living in the same household, according to a study published online Nov. 22 in JAMA Network Open.

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Electronic Health Record Usability Graded F by Physicians

FRIDAY, Nov. 22, 2019 (HealthDay News) — The usability of current electronic health records (EHRs) is classified as unacceptable, with physician-rated EHR usability independently linked to the odds of burnout, according to a study published online Nov. 14 in the Mayo Clinic Proceedings.

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Obesity Prevalence Decreased Modestly for Children in WIC

FRIDAY, Nov. 22, 2019 (HealthDay News) — During 2010 to 2016, there were modest decreases in obesity prevalence among children aged 2 to 4 years enrolled in 73 percent of 56 Special Supplemental Nutrition Program for Women, Infants and Children (WIC) state or territory agencies, according to research published in the Nov. 22 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Massachusetts Passes Bill to Ban All Flavored Vaping Products

FRIDAY, Nov. 22, 2019 (HealthDay News) — A bill banning flavored vaping and tobacco products was passed by the Massachusetts Senate on Thursday and could become the first such statewide legislation in the United States.

AP News Article

Inducing Labor at 41 Weeks May Cut Stillbirth Rates

THURSDAY, Nov. 21, 2019 (HealthDay News) — In women with a low-risk pregnancy, induction at 41 weeks of gestation may be safer than a wait-and-see approach to 42 weeks, according to a study published online Nov. 20 in The BMJ.

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Few Anorexia Nervosa Patients Make Complete Recovery

THURSDAY, Nov. 21, 2019 (HealthDay News) — Caregivers identify distinct components of recovery from eating disorders, although only 20 percent report achievement of full recovery, according to a study published online Nov. 19 in the International Journal of Eating Disorders.

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Employee Premiums, Deductibles Eating Larger Share of Income

THURSDAY, Nov. 21, 2019 (HealthDay News) — During the last decade, health care costs have eaten up a larger share of income for millions of middle-class Americans with employer coverage, according to Trends in Employer Health Care Coverage, 2008-2018, a Nov. 21 report from The Commonwealth Fund.

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Most Infants Susceptible to Measles by 3 Months of Age

THURSDAY, Nov. 21, 2019 (HealthDay News) — In an elimination setting, most infants are susceptible to measles by age 3 months, according to a study published online Nov. 21 in Pediatrics.

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CDC Updates Interim Guidance on Vaping-Linked Lung Illness

WEDNESDAY, Nov. 20, 2019 (HealthDay News) — In an article published in the Nov. 19 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report, interim guidance is provided for health care professionals managing patients with suspected electronic cigarette, or vaping, product use-associated lung injury (EVALI). Another report in the same issue suggests that the characteristics of hospitalized and nonhospitalized EVALI patients are similar.

Abstract/Full Text – Jatlaoui
Abstract/Full Text – Chatham-Stephens

CDC: 63.5 Percent of 3- to 5-Year-Olds Have Had Vision Tested

WEDNEDAY, Nov. 20, 2019 (HealthDay News) — Overall, 63.5 percent of children aged 3 to 5 years have ever had their vision tested, according to a November data brief published by the U.S. Centers for Disease Control and Prevention National Center for Health Statistics.

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~25 Percent of Adolescents, Young Adults Use Rx Opioids

WEDNESDAY, Nov. 20, 2019 (HealthDay News) — Prescription opioid use among teens and young adults is higher than expected, with most obtaining the drugs from friends and family, according to a study published online Nov. 5 in PLOS Medicine.

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Most Infants, Toddlers Consuming Added Sugars

WEDNESDAY, Nov. 20, 2019 (HealthDay News) — Most infants and toddlers consume added sugars in their daily diets, according to a study published online Nov. 14 in the Journal of the Academy of Nutrition and Dietetics.

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Poll: Parents Cite Barriers to Recognizing Depression in Adolescents

WEDNESDAY, Nov. 20, 2019 (HealthDay News) — Two-thirds of parents acknowledge there are barriers to recognizing depression in their own adolescent child, according to a Mott Poll Report, published Nov. 18 by the University of Michigan.

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Prenatal Antidepressant Use May Up Risk for Gestational Diabetes

WEDNESDAY, Nov. 20, 2019 (HealthDay News) — Taking certain antidepressants while pregnant can increase the risk for developing gestational diabetes, according to a study recently published in The BMJ.

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Umbilical Cord Milking May Harm Extremely Preterm Infants

TUESDAY, Nov. 19, 2019 (HealthDay News) — In preterm infants born at less than 32 weeks of gestation, there is no significant difference in the rate for the composite outcome of mortality or severe intraventricular hemorrhage with umbilical cord milking versus delayed umbilical cord clamping, according to a study published in the Nov. 19 issue of the Journal of the American Medical Association, and the study was terminated early due to a significantly higher rate of severe intraventricular hemorrhage in the umbilical cord-milking group.

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AMA, AHA Support Refresher Training for Measuring Blood Pressure

TUESDAY, Nov. 19, 2019 (HealthDay News) — Health care professionals (HCPs) should receive consistent and frequent training in measuring blood pressure (BP), according to a report prepared for the American Medical Association and the American Heart Association and released Nov. 18.

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AAP: Emergency Contraception Should be Given to Sexually Active Teens

TUESDAY, Nov. 19, 2019 (HealthDay News) — Pediatricians should provide emergency contraception (EC) to teenagers who have had unprotected or underprotected intercourse, according to a policy statement from the American Academy of Pediatrics published online Nov. 18 in Pediatrics.

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Optic Nerve Ultrasound May ID Increased Intracranial Pressure

TUESDAY, Nov. 19, 2019 (HealthDay News) — Optic nerve ultrasonography can help diagnose increased intracranial pressure with high specificity and sensitivity for patients with traumatic and nontraumatic brain injury, according to a review published online Nov. 19 in Annals of Internal Medicine.

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White House Wants Hospitals, Insurers to Provide Actual Costs of Care

MONDAY, Nov. 18, 2019 (HealthDay News) — New rules requiring hospitals and insurers to disclose the actual prices for common tests and procedures before they are performed have been proposed by the Trump Administration.

AP News Article

Studies Confirm Safety of 9-Valent HPV Vaccination

MONDAY, Nov. 18, 2019 (HealthDay News) — The safety of the 9-valent human papillomavirus vaccine (9vHPV) has been confirmed, according to two studies published online Nov. 18 in Pediatrics.

Abstract/Full Text – Shimabukuro (subscription or payment may be required)
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Common TB Vaccine Associated With Lower Lung Cancer Rates

MONDAY, Nov. 18, 2019 (HealthDay News) — Childhood vaccination with the bacille Calmette-Guérin (BCG) vaccine is associated with a reduced risk for lung cancer, according to a study published online Sept. 25 in JAMA Network Open.

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Cannabis Use Disorder Has Declined Among Teens, Young Adults

MONDAY, Nov. 18, 2019 (HealthDay News) — Contrary to expectations, the prevalence of cannabis use disorder (CUD) decreased significantly among individuals reporting daily/almost daily cannabis use between 2002 and 2016, according to a study published in the Dec. 1 issue of Drug and Alcohol Dependence.

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CDC: Number of Vaping-Linked Lung Illnesses Up to 2,172

FRIDAY, Nov. 15, 2019 (HealthDay News) — The number of Americans stricken with a severe respiratory illness tied to vaping has now reached 2,172, the U.S. Centers for Disease Control and Prevention reported Thursday. That is a rise from the 2,051 case total from a week ago.

More Information: CDC
CNN Article

About 2.7 Million ED Visits Reported for Sports Injuries in 2010 to 2016

FRIDAY, Nov. 15, 2019 (HealthDay News) — About 2.7 million emergency department visits for sports injuries occurred during 2010 to 2016, according to a study published online Nov. 15 in the National Health Statistics Reports, a publication of the U.S. Centers for Disease Control and Prevention.

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Childhood Episode of Pancreatitis May Up Risk for Diabetes Later

FRIDAY, Nov. 15, 2019 (HealthDay News) — A history of a clinically resolved, single event of acute pancreatitis in childhood is associated with an increased risk for diabetes during young adulthood, according to a study published online Nov. 6 in Diabetes Care.

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Survey of U.S. Registered Nurses Points to Worsening Shortages

THURSDAY, Nov. 14, 2019 (HealthDay News) — The 2019 AMN Healthcare Survey of Registered Nurses raises concerns about the outlook for the nursing profession in the United States.

2019 Survey of Registered Nurses

Minimum Age to Buy Tobacco, E-Cigarettes Raised in NY State

THURSDAY, Nov. 14, 2019 (HealthDay News) — The minimum age to buy tobacco and electronic cigarette products in New York State is now 21.

CNN Article

Surgery for Congenital Heart Disease Tied to Kidney Disease

THURSDAY, Nov. 14, 2019 (HealthDay News) — The risk for mortality and end-stage kidney disease (ESKD) is high in children who undergo surgical repair for congenital heart disease compared with the general population, according to a study published in the October issue of the Clinical Journal of the American Society of Nephrology.

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Health Groups Urge President to Ban All Flavored E-Cigarettes

WEDNESDAY, Nov. 13, 2019 (HealthDay News) — An ad campaign urging U.S. President Donald Trump to follow through on a commitment to ban all flavored electronic cigarettes, including mint and menthol, has been launched by a number of public health groups.

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Cannabis Use Disorder Up With Recreational Pot Legalization

WEDNESDAY, Nov. 13, 2019 (HealthDay News) — Cannabis use disorder (CUD) has increased among adolescents and adults (≥26 years) after recreational marijuana legalization (RML) enactment, according to a study published online Nov. 13 in JAMA Psychiatry.

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Invasive Melanoma Incidence Decreasing in Teens, Young Adults

WEDNESDAY, Nov. 13, 2019 (HealthDay News) — Melanoma incidence seems to be decreasing in adolescents and young adults, according to a study published online Nov. 13 in JAMA Dermatology.

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Imaging Rates Continue to Rise Despite Efforts to Reduce

WEDNESDAY, Nov. 13, 2019 (HealthDay News) — Despite initiatives to reduce the use of medical imaging, rates continue to rise in both the United States and Ontario, Canada, according to a study recently published in the Journal of the American Medical Association.

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Early Childhood High BMI Tied to Maternal Prepregnancy Factors

WEDNESDAY, Nov. 13, 2019 (HealthDay News) — A child’s high and increasing body mass index (BMI) between ages 2 and 6 years is strongly associated with maternal prepregnancy weight, according to a study published online Nov. 5 in Pediatric Obesity.

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Pediatric Liver Transplant Recipients Often Undervaccinated

TUESDAY, Nov. 12, 2019 (HealthDay News) — Many pediatric liver transplant recipients are undervaccinated, according to a research letter published in the Nov. 12 issue of the Journal of the American Medical Association.

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Double Lung Transplant Performed for Vaping-Related Illness

TUESDAY, Nov. 12, 2019 (HealthDay News) — What is believed to be the first double lung transplant in the United States for a patient whose lungs were irreparably damaged after vaping was performed by doctors at the Henry Ford Health System in Detroit.

CNN Article

EPA Proposal Would Limit Use of Science in Public Health Rules

TUESDAY, Nov. 12, 2019 (HealthDay News) — Scientists and doctors are sounding the alarm about a Trump administration proposal to significantly limit the use of scientific and medical research in setting public health regulations. They warn that the new Environmental Protection Agency rule would weaken the scientific basis of government policymaking, The New York Times reported.

The New York Times Article

Sesame-Specific IgE Levels May Help Diagnose Allergies

FRIDAY, Nov. 8, 2019 (HealthDay News) — Sesame immunoglobulin E (IgE) levels may have diagnostic utility for sesame allergy, according to a letter to the editor published online Oct. 28 in Pediatric Allergy and Immunology.

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Juul Stops Sales of Mint-Flavored E-Cigarettes

FRIDAY, Nov. 8, 2019 (HealthDay News) — Juul Labs will halt sales of its mint-flavored electronic cigarettes, the company announced Thursday.

AP News Article

CDC: Number of Vaping-Linked Lung Illnesses Tops 2,000

THURSDAY, Nov. 7, 2019 (HealthDay News) — The number of Americans stricken with a severe respiratory illness tied to vaping has now reached 2,051, the U.S. Centers for Disease Control and Prevention reported Thursday.

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Tx Choice for T2DM in Obese Teens Tied to Later Kidney Disease Risk

THURSDAY, Nov. 7, 2019 (HealthDay News) — For severely obese adolescents with type 2 diabetes (T2D), medical therapy is associated with increased odds of diabetic kidney disease (DKD) at five years compared with metabolic bariatric surgery, according to a study published online Nov. 4 in Diabetes Care.

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San Francisco Vaping Ban Upheld by Voters

WEDNESDAY, Nov. 6, 2019 (HealthDay News) — A ban on electronic cigarette sales in San Francisco was widely backed by voters despite the city being home to Juul Labs, which dominates the e-cigarette market in the United States.

Forbes Article

Serious Eating Disorder Possible Even at Normal Body Weight

WEDNESDAY, Nov. 6, 2019 (HealthDay News) — Large, rapid weight loss is the best predictor of medical and psychological problems in patients with atypical anorexia nervosa (AAN), not their body weight at diagnosis, according to a study published online Nov. 5 in Pediatrics.

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2010 to 2016 Saw Increase in Teens Admitted to ED for Abuse

TUESDAY, Nov. 5, 2019 (HealthDay News) — From 2010 to 2016, there was an increase in the number of adolescents admitted to emergency departments for confirmed sexual abuse, according to a research letter published online Nov. 4 in JAMA Pediatrics.

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Prevalence of E-Cigarette Use High Among U.S. Preteens, Teens

TUESDAY, Nov. 5, 2019 (HealthDay News) — The prevalence of self-reported current electronic cigarette use is high among U.S. middle and high school students, according to a study published online Nov. 5 in the Journal of the American Medical Association.

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Medical Practices Burdened by Regulatory Requirements

TUESDAY, Nov. 5, 2019 (HealthDay News) — The vast majority of group medical practices report that regulatory requirements, including prior authorization and quality payment programs, are burdensome, according to a survey released by the Medical Group Management Association.

Annual Regulatory Burden Survey

Effect of Legislation on School Vaccination Rates May Be Limited

TUESDAY, Nov. 5, 2019 (HealthDay News) — Assuming the current rates of medical exemptions persist, the overall exemption rate in California schools is expected to stabilize at 1.87 percent by 2027, according to a research letter published online Nov. 5 in the Annals of Internal Medicine.

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Editorial (subscription or payment may be required)

Dr. Stephen Hahn Nominated to Head FDA

MONDAY, Nov. 4, 2019 (HealthDay News) — Radiation oncology expert Stephen Hahn, M.D., has been nominated as the new U.S. Food and Drug Administration commissioner.

CNN Article

2007 to 2016 Saw Increase in Child Psychiatrists in U.S.

MONDAY, Nov. 4, 2019 (HealthDay News) — The number of child psychiatrists has increased in the United States, although there is considerable regional variability, according to a study published online Nov. 4 in Pediatrics.

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Religious Exemption Rate for Vaccination Up in 2017 to 2018

MONDAY, Nov. 4, 2019 (HealthDay News) — The rate of religious exemptions for vaccination among kindergartners is associated with the availability of personal belief exemptions, according to a study published online Nov. 4 in Pediatrics.

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Risk for Death, Suicide Up in Teens Who Visit ED for Self-Harm

MONDAY, Nov. 4, 2019 (HealthDay News) — Adolescents with emergency department visits for self-harm have increased rates of recurrent self-harm, mortality, and suicide, according to a study published online Nov. 4 in CMAJ, the journal of the Canadian Medical Association.

Abstract/Full Text

CDC: 1 Dead, 8 Hospitalized in Salmonella Outbreak Tied to Ground Beef

MONDAY, Nov. 4, 2019 (HealthDay News) — Ground beef tainted with Salmonella has led to 10 known infections across six states, including eight people who were hospitalized, and one death.

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Recommendations Developed to Address Clinician Burnout

FRIDAY, Nov. 1, 2019 (HealthDay News) — In Taking Action Against Clinician Burnout, a new report published online Oct. 23 by the National Academies of Sciences, Engineering, and Medicine, recommendations are presented to address clinician burnout.

Taking Action Against Clinician Burnout

2007 to 2016 Saw Rise in ADHD Prevalence in Adults, Children

FRIDAY, Nov. 1, 2019 (HealthDay News) — From 2007 to 2016, the prevalence of attention-deficit/hyperactivity disorder (ADHD) increased among adults and children, according to a study published online Nov. 1 in JAMA Network Open.

Abstract/Full Text

Risk for Birth Defects Not Increased With Adalimumab

FRIDAY, Nov. 1, 2019 (HealthDay News) — Adalimumab exposure in pregnancy does not increase the risk for birth defects, according to a study published online Oct. 18 in PLOS ONE.

Abstract/Full Text

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