TUESDAY, Jan. 7, 2020 (HealthDay News) — Dual use of electronic cigarettes and combustible cigarettes is associated with increased odds of stroke compared with not smoking or sole combustible cigarette use, according to a study published online Jan. 7 in the American Journal of Preventive Medicine.

Tarang Parekh, M.B.B.S., from George Mason University in Fairfax, Virginia, and colleagues analyzed pooled data from the Behavior Risk Factor Surveillance System from 2016 to 2017 for a sample of 161,529 participants aged 18 to 44 years to examine the association between e-cigarette use and stroke.

The researchers found that the odds of stroke were increased for current dual use of e-cigarettes and combustible cigarettes compared with not smoking (adjusted odds ratio, 2.91; 95 percent confidence interval, 1.62 to 5.25) and compared with current sole combustible cigarette use (adjusted odds ratio, 1.83; 95 percent confidence interval, 1.06 to 3.17). The odds of stroke did not differ for current sole e-cigarette smokers compared with nonsmokers (adjusted odds ratio, 0.69; 95 percent confidence interval, 0.34 to 1.42). Compared with current sole combustible cigarette users, sole e-cigarette users had significantly lower odds of stroke (adjusted odds ratio, 0.43; 95 percent confidence interval, 0.20 to 0.93).

“These findings emphasize the critical need to conduct longitudinal studies exploring the clear benefit and risks of current smoking-cessation alternatives,” the authors write.

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