OR of SNM traditionally has been the gold standard for treatment. However, the ER has recently become a surgical alternative. This study aimed to compare survival outcomes between OR and ER of SNM.
Researchers performed a literature search on PubMed, Embase, Cochrane Library, Web of Science, ClinicalTrials.gov, and Google Scholar. Two reviewers independently screened for original studies comparing survival outcomes between OR and ER for SNM. Data were systematically collected on study design, patient demographics, results, and level of evidence. Quality assessment was performed using the NOS.
The initial search yielded 2078 abstracts, of which nine cohort studies were included for 510 patients from 6 different countries. The average quality of all included studies using the NOS was 7.7 stars. Six out of 7 reviews reported no differences in the stages of SNM between patients receiving ER versus OR. Overall survival was longer in the ER group versus the OR group. There was no significant difference in disease-free survival between groups.
The study concluded that based on the available literature, an endoscopic approach for SNM resection has survival outcomes that are similar or greater compared to an open system.
Reference: https://journals.sagepub.com/doi/full/10.1177/1945892418822637
