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Overall Risk of VTE Recurrence Similar for iSVT, Proximal DVT

Overall Risk of VTE Recurrence Similar for iSVT, Proximal DVT
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FRIDAY, March 31, 2017 (HealthDay News) — Patients with isolated superficial vein thrombosis (iSVT) have a similar overall risk of recurrence as those with proximal deep vein thrombosis (DVT), according to a study published online March 20 in the Journal of Thrombosis and Haemostasis.

Jean-Philippe Galanaud, M.D., Ph.D., from Montpellier University in France, and colleagues used data from a prospective, multicenter study to examine the risk and type of venous thromboembolic (VTE) recurrence at three years and after anticoagulants were stopped. Recurrence was assessed for 285 patients with a first objectively confirmed iSVT without cancer and 262 patients with a first proximal DVT without cancer.

The researchers found that iSVT patients had a similar overall incidence of VTE recurrence compared with proximal DVT patients (5.4 versus 6.5 percent per patient-year; adjusted hazard ratio, 0.9; 95 percent confidence interval, 0.5 to 1.6), but they had increased risk of iSVT recurrence (2.7 versus 0.6 percent; adjusted hazard ratio, 5.9; 95 percent confidence interval, 1.3 to 27.1) and reduced risk of deep-VTE events (2.5 versus 5.9 percent; adjusted hazard ratio, 0.4; 95 percent confidence interval, 0.2 to 0.9).

“In patients with a first iSVT without cancer, after stopping anticoagulants, the incidence of deep-VTE recurrence is twice lower than that of proximal DVT patients but overall risk of recurrence is similar,” the authors write.

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