For the best prognosis and care of interstitial lung disease, a correct diagnosis is critical. Despite the fact that connective tissue disease is one of the most prevalent causes of interstitial lung disease, some people experience autoimmunity-like symptoms without satisfying the diagnostic criteria for a particular connective tissue disease. A 2015 research statement established consensus-based criteria and created the phrase “interstitial pneumonia with autoimmune characteristics” to better describe and investigate this disease entity more universally (IPAF). Researchers describe and evaluate previously suggested criteria to characterize these individuals in this review, as well as present an overview of the IPAF criteria and highlight current studies targeted at defining IPAF cohorts. Following that, they address questions that have emerged as a result of the implementation of the IPAF criteria, as well as prospective research prospects.
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