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Parathyroid hormone serum concentration in Central European patients with non-ischemic heart failure as a potential marker of disease severity and poor prognosis.

Parathyroid hormone serum concentration in Central European patients with non-ischemic heart failure as a potential marker of disease severity and poor prognosis.
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Kubiak GM, Kolaszko A, Nowalany-Kozielska E,


Kubiak GM, Kolaszko A, Nowalany-Kozielska E, (click to view)

Kubiak GM, Kolaszko A, Nowalany-Kozielska E,

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Endokrynologia Polska 2017 02 23() doi 10.5603/EP.a2016.0057
Abstract

IntroductionParathyroid hormone (PTH) might be considered as a potential marker of disease severity and worse prognosis in heart failure (HF) patients. ObjectivesTo assess PTH, vitamin D, phosphorus (P) and total calcium (Ca2+) serum concentrations in Central European patients suffering from HF of non-ischemic origin compared to non-HF volunteers.To evaluate potential correlations among the enumerated parameters, established markers of worse prognosis and declared sun exposure. Patients and methodsSerum intact-PTH, 25-OH vitamin D, P and total Ca2+ concentrations were assessed in a group of HF patients and non-HF volunteers. Patients described their daily profile of sun exposure during the last eight weeks as "above" or "below" seven hours a week.ResultsThe mean PTH concentrations in the non-ischemic HF group and control group were 79.5 pg/mL and 59.6 pg/mL, respectively (P=0.009). Non-HF volunteers declaring higher sun exposure time had higher serum concentrations of vitamin D compared to those with lower sun exposure time (30.3 vs. 23.8 ng/mL, P.

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