Women with long-term persistence of human papillomavirus (HPV) infection appear to be generally more susceptible to other HPV infections, especially longer-lasting infections, than women who have these infections cleared, according to an international investigation. In a logistic regression model, women with long-term HPV persistence were more likely than women who cleared infections to have another newly-detected HPV infection detected when assessed at three or more office visits (odds ratio, 2.6).