Between 2010 and 2015, we examined pertussis epidemic trends in Brazil. The study also looked at tetanus, diphtheria, and acellular pertussis (Tdap) vaccination coverage among pregnant women from 2014 to 2016, the year the Tdap maternal immunization guideline was introduced in Brazil. On the basis of Brazilian public surveillance databases, epidemiological statistics regarding incidence, prevalence, hospitalization, death, and maternal vaccination coverage were computed. The findings of the epidemiological data analysis revealed that the pertussis average incidence rate (IR) for all ages was 2.19/100,000 people, with a peak in 2014 and the greatest incidence among 1-year-old children. One-year-old children accounted for 97.6 percent of pertussis fatalities. In 2014, 9.2 percent of mothers were immunized, 40.4 percent in 2015, and 33.8 percent in 2016.

Pertussis incidence and fatalities rose in Brazil from 2010 to 2014, but dropped in 2015. Tdap vaccination coverage among pregnant women was low and varied by area in the two years after the NIP recommendation, 2015 and 2016. More initiatives and national programs would aid in increasing maternal vaccination coverage and knowledge.